Diverse outcomes of controlled human malaria infection originate from host intrinsic immune variation and not var gene switching
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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Falciparum malaria is clinically heterogeneous and yet in most cases the risk of life-threatening disease dramatically declines after the first few infections of life because children rapidly acquire disease tolerance (resistance to severe malaria without improved control of parasite burden). Identifying the factors that determine clinical outcome in a malaria-naive host is therefore paramount to reduce malaria mortality. However, the relative contribution of disease-causing variants of the ... (Show More)
|Illumina HiSeq 2500||30|