Molecular profiling of DLBCL patients treated in the HOVON84 trial
|Study ID||Alternative Stable ID||Type|
Using a comprehensive NGS assay for simultaneous screening of mutations, copy number alterations, and translocations, 5 biology-based risk profiles could be reproduced in a Dutch DLBCL population and validated for outcome prediction. This approach will enable application as a diagnostic tool to select DLBCL patients for risk adapted treatment and help to develop biomarker-driven clinical trials for personalized medicine.
Study Datasets 1 dataset.
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Shallow whole genome sequencing and targeted sequencing of DLBCL patients treated in the HOVON84 trial
|Illumina HiSeq 4000||220|