CRISPR-based adenine editors correct nonsense mutations in a cystic fibrosis organoid biobank.
|Study ID||Alternative Stable ID||Type|
|EGAS00001003951||Whole Genome Sequencing|
Study Datasets 1 dataset.
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Three SpCas9-ABE (R785X/R785X) and three xCas9-ABE-repaired organoid clones (F508del/R553X) and their respective unrepaired control organoids were paired-end whole genome sequenced using Illumina Novaseq 6000 system. The reads were mapped to hg19 genome assembly and data is provided as BAM files.
|Illumina NovaSeq 6000||8|