Whole genome sequencing of Cas9 repaired cystic fibrosis organoids description

Three SpCas9-ABE (R785X/R785X) and three xCas9-ABE-repaired organoid clones (F508del/R553X) and their respective unrepaired control organoids were paired-end whole genome sequenced using Illumina Novaseq 6000 system. The reads were mapped to hg19 genome assembly and data is provided as BAM files.

8 samples
DAC: EGAC00001001864
Technology: Illumina NovaSeq 6000

Access Policy1 Study Files

Metadata

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DS DUO:0000007 (version: 2019-01-07)disease specific researchThis data use permission indicates that use is allowed provided it is related to the specified disease.ModifiersMONDO:0006517

The Princess Maxima Center for pediatric oncology default access policy to enable re-production of research and re-use of data for scientific purposes.

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID	Study Title	Study Type
EGAS00001003951	CRISPR-based adenine editors correct nonsense mutations in a cystic fibrosis organoid biobank.	Whole Genome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID	File Type	Size
EGAF00002799944	bam	46.4 GB
EGAF00002799945	bam	44.9 GB
EGAF00002799946	bam	41.8 GB
EGAF00002799947	bam	47.4 GB
EGAF00002799948	bam	53.3 GB
EGAF00002799949	bam	44.7 GB
EGAF00002799950	bam	40.2 GB
EGAF00002799951	bam	43.5 GB
8 Files (362.3 GB)