Study

Imaging metabolic heterogeneity in breast cancer using hyperpolarized 13C-MRI

Study ID Alternative Stable ID Type
EGAS00001004118 Other

Study Description

Higher 13C-lactate labeling was seen in the more aggressive tumors, including all triple negative breast cancers. There was a significant correlation between lactate labeling and expression of the monocarboxylate transporter (MCT1), which mediates tumor cell pyruvate uptake, and a weaker correlation with expression of LDHA, which catalyzes label exchange between the injected pyruvate and the endogenous lactate pool.

Study Datasets 1 dataset.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001005760
Transcriptomics for samples obtained from six patients (MBR01, MBR03, MBR05, MBR07, MBR10, MBR11)
Illumina HiSeq 2500 14

Who archives the data?

Publications

Citations

Retrieving...
Retrieving...