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In this project we aimed to assess the transcriptional consequences of disrupting FAM50A in TOV21G cells in vivo. To do this we generated a dox inducible FAM50A gRNA allele such that we could conditionally inactivate FAM50A by feeding mice a diet containing doxycycline. Tumour masses were harvested from mice when they reached the ethical limit and RNA was extracted for RNA-Seq analysis.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001006649 Illumina HiSeq 4000 Illumina NovaSeq 6000 55
Publications Citations
Combinatorial CRISPR screen identifies fitness effects of gene paralogues.
Nat Commun 12: 2021 1302