HDAC3 mediates the inflammatory response and LPS tolerance in human monocytes and macrophages

Study ID Alternative Stable ID Type
EGAS00001004218 RNASeq

Study Description

Study Datasets 1 dataset.

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Dataset ID Description Technology Samples
In this experiment we investigated the effect of HDAC3 inhibition on the transcriptome of IFNg-primed macrophages under different tolerization conditions. Peripheral blood mononuclear cells (PBMCs) were isolated from 3 healthy donors. PBMCs were isolated from whole blood of healthy donors using Ficoll gradient (Invitrogen). Monocytes (CD14+ cells) were positively selected from PBMCs using CD14 Microbeads according to the manufacturer’s instructions (Miltenyi Biotec). Monocytes were ... (Show More)
Illumina HiSeq 4000 18

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