Study
HDAC3 mediates the inflammatory response and LPS tolerance in human monocytes and macrophages
Study ID | Alternative Stable ID | Type |
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EGAS00001004218 | RNASeq |
Study Description
Study Datasets 1 dataset.
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Dataset ID | Description | Technology | Samples |
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EGAD00001005959 |
In this experiment we investigated the effect of HDAC3 inhibition on the transcriptome of IFNg-primed macrophages under different tolerization conditions. Peripheral blood mononuclear cells (PBMCs) were isolated from 3 healthy donors. PBMCs were isolated from whole blood of healthy donors using Ficoll gradient (Invitrogen). Monocytes (CD14+ cells) were positively selected from PBMCs using CD14 Microbeads according to the manufacturer’s instructions (Miltenyi Biotec). Monocytes were ... (Show More)
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Illumina HiSeq 4000 | 18 |
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