Immunogenomic landscape of hematological malignancies - EGA European Genome-Phenome Archive

Study ID	Alternative Stable ID	Type
EGAS00001004444		Other

Study ID

Alternative Stable ID

Type

EGAS00001004444

Other

Study Description

We integrated over 8,000 transcriptomes and over 2,000 samples with multilevel genomic data of hematological cancers to investigate how immunological features are linked to cancer subtypes, genetic and epigenetic alterations, and patient survival. For more detailed follow-up analyses in acute myeloid leukemia (AML), single-cell RNA sequencing was performed on 8 AML bone marrow samples at diagnosis to profile the phenotypes of blasts and infiltrating immune cells in different disease subtypes.

Dataset ID	Description	Technology	Samples
EGAD00001006173	Single-cell RNA sequencing was performed on bone marrow mononuclear cells from 8 acute myeloid leukemia patients at diagnosis. The profiling was performed using 10x Genomics 3' (5 samples) and 5' (3 samples) platforms. The raw data are available as fastq files. Single-cell RNA sequencing was performed on bone marrow mononuclear cells from 8 acute myeloid leukemia patients at diagnosis. The profiling was performed using 10x Genomics 3' (5 samples) and 5' (3 samples) platforms. The raw data are available as fastq files.	Illumina HiSeq 2500,Illumina NovaSeq 6000	128

Dataset ID

Description

Technology

Samples

EGAD00001006173

Single-cell RNA sequencing was performed on bone marrow mononuclear cells from 8 acute myeloid leukemia patients at diagnosis. The profiling was performed using 10x Genomics 3' (5 samples) and 5' (3 samples) platforms. The raw data are available as fastq files.

Illumina HiSeq 2500,Illumina NovaSeq 6000

128

Study

Study Description

Study Datasets 1 dataset.

Who archives the data?

Publications

Citations

The European Genome-phenome Archive (EGA) is part of the ELIXIR infrastructure.