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Cell types of the human retina and its organoids at single-cell resolution. Cowan et al

Human organoids recapitulating the cell-type diversity and function of their target organ are valuable for basic and translational research. We developed light-sensitive human retinal organoids with multiple nuclear and synaptic layers, and functional synapses. We sequenced the RNA of 285,441 single cells from these organoids at seven developmental time points and from the periphery, fovea, pigment epithelium and choroid of light-responsive adult human retinas.

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Dataset ID Description Technology Samples
EGAD00001006350 Illumina HiSeq 2500 124
Publications Citations
Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution.
Cell 182: 2020 1623-1640.e34