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Cell types of the human retina and its organoids at single-cell resolution. Cowan et al

Human organoids recapitulating the cell-type diversity and function of their target organ are valuable for basic and translational research. We developed light-sensitive human retinal organoids with multiple nuclear and synaptic layers, and functional synapses. We sequenced the RNA of 285,441 single cells from these organoids at seven developmental time points and from the periphery, fovea, pigment epithelium and choroid of light-responsive adult human retinas.

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Team controlling the access of the human retina and human retinal organoid data generated from the collaboration between IOB and Novartis and included in the paper Cowan et al., 2020

DATA ACCESS AGREEMENT This agreement governs the terms on which access will be granted to the genotype data generated by Institute of Molecular and Clinical Ophthalmology Basel (IOB), Mittlere Strasse 91, 4031 Basel, Switzerland, and Novartis Pharma AG Lichtstrasse 35, 4056 Basel, Switzerland (together “Data Controllers”). In signing this agreement, You are agreeing to be bound by the terms and conditions of access set out in this agreement. For the sake of clarity, the terms of access set out in this agreement apply both to the User and the User’s Institution (as defined below). User Institution and User are referred to within the agreement as “You” and “Your” shall be construed accordingly. Definitions: Data means all and any human genetic data of the Data Controllers you may access from the data base of the European Genome-phenome Archive (EGA).
 Data Subject means a person, who has been informed of the purpose for which the Data is held and has given his/her informed consent thereto. User means a researcher whose User Institution has previously completed this Data Access Agreement and has received acknowledgement of its acceptance. Publications means, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. User Institution means the organisation at which the User is employed, affiliated or enrolled. Terms and Conditions: In signing this Agreement: 1. You agree to use the Data only for the advancement of medical research. 

 2. You agree to preserve, at all times, the confidentiality of information and Data pertaining to Data Subjects. In particular, You undertake not to use, or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. 
 3. You agree not to transfer or disclose the Data, in whole or part, or any identifiable material derived from the Data, to others. Should You wish to share the Data with a third party, that third party must make a separate application for access to the Data. 
 4. You agree to acknowledge in any work based in whole or part on the Data, the published paper from which the Data derives, the version of the data, and the role of the Data Controllers and the relevant primary collectors and their funders. 5. You accept that the Data Controllers 
a) bear no legal responsibility for the accuracy or comprehensiveness of the Data; and 
b) accept no liability for indirect, consequential, or incidental, damages or losses arising from use of the Data, or from the unavailability of, or break in access to, the Data for whatever reason. 
 6. You understand and acknowledge that the Data is protected by copyright and other intellectual property rights, and that duplication, except as reasonably required to carry out Your research with the Data, or sale of all or part of the Data on any media is not permitted. 
 7. You recognize that nothing in this agreement shall operate to transfer to the User Institution any intellectual property rights relating to the Data. The User Institution has the right to develop intellectual property based on comparisons with their own data. 
 8. You accept that this agreement will terminate immediately upon any breach of this agreement by You and You will be required to destroy any Data held. 
 9. You accept that it may be necessary for the Data Controllers or its appointed agent to alter the terms of this agreement from time to time in order to address new concerns. In this event, the Data Controllers or its appointed agent will contact You to inform You of any changes and You agree that Your continued use of the Data shall be dependent on the parties entering into a new version of the Agreement. 
 10. You accept that the Data is subject to laws for data protection and to rights granted thereunder to the Data Subject and that You are responsible for ensuring compliance with any such applicable law and rights claimed thereunder by the Data Subject. The Data Controllers Data Access Committee reserves the right to request and inspect data security and management documentation to ensure the adequacy of data protection measures in countries that have no national laws comparable to that which pertain in the EAA. 
 11. This agreement shall be construed, interpreted and governed by the laws of Switzerland and shall be subject to the jurisdiction of the Courts Basel-Stadt. 
   For and on behalf of User: _____________________________________ Name of Applicant(s): _____________________________________ Signature of Applicant(s): _____________________________________ Date: _____________________________________ For and on behalf of User Institution: ______________________________________ Signature of Institutional or Administrative Authority: ______________________________________ Print name: ______________________________________ User Institution: ______________________________________ Date: ______________________________________ WHEN SUBMITTING THIS DOCUMENT, PLEASE INCLUDE ALL PAGES OF THE AGREEMENT WITH THIS SIGNATURE PAGE

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001004561 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00004257399 bam 42.4 GB
EGAF00004257400 bam 41.3 GB
EGAF00004257401 bam 50.5 GB
EGAF00004257402 bam 59.5 GB
EGAF00004257403 bam 11.8 GB
EGAF00004257404 bam 11.9 GB
EGAF00004257405 bam 11.7 GB
EGAF00004257406 bam 11.6 GB
EGAF00004257407 bam 11.5 GB
EGAF00004257408 bam 24.7 GB
EGAF00004257409 bam 12.7 GB
EGAF00004257410 bam 11.1 GB
EGAF00004257411 bam 22.7 GB
EGAF00004257412 bam 10.7 GB
EGAF00004257413 bam 7.4 GB
EGAF00004257414 bam 6.1 GB
EGAF00004257415 bam 7.0 GB
EGAF00004257416 bam 14.0 GB
EGAF00004257417 bam 13.0 GB
EGAF00004257418 bam 11.0 GB
EGAF00004257419 bam 8.6 GB
EGAF00004257420 bam 12.2 GB
EGAF00004257421 bam 8.1 GB
EGAF00004257422 bam 4.8 GB
EGAF00004257423 bam 4.5 GB
EGAF00004257424 bam 4.1 GB
EGAF00004257425 bam 6.5 GB
EGAF00004257426 bam 7.7 GB
EGAF00004257427 bam 8.2 GB
EGAF00004257428 bam 8.3 GB
EGAF00004257429 bam 8.1 GB
EGAF00004257430 bam 8.6 GB
EGAF00004257431 bam 34.4 GB
EGAF00004257432 bam 37.8 GB
EGAF00004257433 bam 43.1 GB
EGAF00004257434 bam 31.1 GB
EGAF00004257435 bam 32.7 GB
EGAF00004257436 bam 34.6 GB
EGAF00004257437 bam 21.9 GB
EGAF00004257438 bam 31.9 GB
EGAF00004257439 bam 60.8 GB
EGAF00004257440 bam 44.7 GB
EGAF00004257441 bam 34.4 GB
EGAF00004257442 bam 37.9 GB
EGAF00004257443 bam 39.5 GB
EGAF00004257444 bam 24.5 GB
EGAF00004257445 bam 14.6 GB
EGAF00004257446 bam 6.3 GB
EGAF00004257447 bam 14.0 GB
EGAF00004257448 bam 6.3 GB
EGAF00004257449 bam 17.0 GB
EGAF00004257450 bam 9.1 GB
EGAF00004257451 bam 21.0 GB
EGAF00004257452 bam 7.5 GB
EGAF00004257453 bam 6.7 GB
EGAF00004257454 bam 7.7 GB
EGAF00004257455 bam 7.4 GB
EGAF00004257456 bam 6.7 GB
EGAF00004257457 bam 7.5 GB
EGAF00004257458 bam 3.6 GB
EGAF00004257459 bam 6.1 GB
EGAF00004257460 bam 9.4 GB
EGAF00004257461 bam 6.8 GB
EGAF00004257462 bam 7.2 GB
EGAF00004257463 bam 8.0 GB
EGAF00004257464 bam 12.0 GB
EGAF00004257465 bam 8.8 GB
EGAF00004257466 bam 4.8 GB
EGAF00004257467 bam 3.4 GB
EGAF00004257468 bam 5.1 GB
EGAF00004257469 bam 5.1 GB
EGAF00004257470 bam 4.3 GB
EGAF00004257471 bam 9.1 GB
EGAF00004257472 bam 10.7 GB
EGAF00004257473 bam 7.6 GB
EGAF00004257474 bam 6.9 GB
EGAF00004257475 bam 6.7 GB
EGAF00004257476 bam 6.2 GB
EGAF00004257477 bam 6.4 GB
EGAF00004257478 bam 8.8 GB
EGAF00004257543 bam 7.1 GB
EGAF00004257544 bam 7.6 GB
EGAF00004257545 bam 8.3 GB
EGAF00004257546 bam 7.1 GB
EGAF00004257547 bam 5.6 GB
EGAF00004257548 bam 6.4 GB
EGAF00004257549 bam 5.9 GB
EGAF00004257550 bam 7.0 GB
EGAF00004257551 bam 5.8 GB
EGAF00004257552 bam 7.5 GB
EGAF00004257553 bam 8.0 GB
EGAF00004257554 bam 7.2 GB
EGAF00004257555 bam 7.0 GB
EGAF00004257556 bam 8.5 GB
EGAF00004257557 bam 9.0 GB
EGAF00004257558 bam 5.5 GB
EGAF00004257559 bam 4.7 GB
EGAF00004257560 bam 5.7 GB
EGAF00004257561 bam 5.1 GB
EGAF00004257562 bam 6.0 GB
EGAF00004257563 bam 7.5 GB
EGAF00004257564 bam 12.0 GB
EGAF00004257565 bam 6.7 GB
EGAF00004257566 bam 11.8 GB
EGAF00004257567 bam 13.1 GB
EGAF00004257568 bam 9.2 GB
EGAF00004257569 bam 1.9 GB
EGAF00004257570 bam 14.0 GB
EGAF00004257571 bam 8.0 GB
EGAF00004257572 bam 9.4 GB
EGAF00004257573 bam 8.8 GB
EGAF00004257574 bam 5.2 GB
EGAF00004257575 bam 10.5 GB
EGAF00004257576 bam 3.3 GB
EGAF00004257577 bam 7.6 GB
EGAF00004257578 bam 4.7 GB
EGAF00004257579 bam 8.6 GB
EGAF00004257580 bam 8.4 GB
EGAF00004257581 bam 8.0 GB
EGAF00004257582 bam 15.6 GB
EGAF00004257583 bam 10.4 GB
EGAF00004257584 bam 18.0 GB
EGAF00004257585 bam 13.5 GB
EGAF00004257586 bam 12.2 GB
124 Files (1.6 TB)