Study

scRNAseq of human primary nasal epithelium differentiated at air-liquid interface exposed to SARS-CoV2

Study ID Alternative Stable ID Type
EGAS00001005633 Other

Study Description

The nasal epithelium is a plausible entry point for SARS-CoV-2, a site of pathogenesis and transmission, and may initiate the host response to SARS-CoV-2. Antiviral interferon responses are critical to outcome of SARS-CoV-2. Yet little is known about the interaction between SARS-CoV-2 and innate immunity in this tissue. Here we applied single-cell RNA sequencing and proteomics to a primary cell model of human primary nasal epithelium differentiated at air-liquid interface.

Study Datasets 1 dataset.

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Dataset ID Description Technology Samples
EGAD00001008159
Single cell RNA sequence generated from human primary nasal epithelium differentiated at air-liquid interface. This dataset comprises tissue from two donors, with cultures either unexposed or exposed to SARS-CoV2. Libraries were prepared using the 10X Genomics pipeline as per manufacturer's instructions.
NextSeq 500 24

Who archives the data?

There are no publications available