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SARS-CoV2 nasal epithelium

Single cell RNA sequence generated from human primary nasal epithelium differentiated at air-liquid interface. This dataset comprises tissue from two donors, with cultures either unexposed or exposed to SARS-CoV2. Libraries were prepared using the 10X Genomics pipeline as per manufacturer's instructions.

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Adapted Wellcome DAC

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Terms and Conditions: In signing this Agreement: 1. You agree to use the Data only for the advancement of medical research, according to the consent obtained from sample donors. 2. You agree to preserve, at all times, the confidentiality of information and Data pertaining to Data Subjects. In particular, You undertake not to use, or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. 3. You agree not to attempt to link the data provided under this agreement to other information or archive data available for the data sets provided, even if access to that data has been formally granted to you, or it is freely available without restriction, without specific permission being sought from the relevent access committees. 4. You agree not to transfer or disclose the Data, in whole or part, or any identifiable material derived from the Data, to others, except as necessary for data/safety monitoring or programme management. Should You wish to share the Data with a collaborator outwith the same Institution, the third party must make a separate application for access to the Data. 5. You agree to use the data for the approved purpose and project described in your application; use of the data for a new purpose or project will require a new application and approval. 6. You accept that Data will be reissued from time to time, with suitable versioning. If the reissue is at the request of sample donors and/or other ethical scrutiny, You will destroy earlier versions of the Data. 7. You accept that the the original data creators or the funders of the Data or any part of the Data supplied: a) bear no legal responsibility for the accuracy or comprehensiveness of the Data; and b) accept no liability for indirect, consequential, or incidental, damages or losses arising from use of the Data, or from the unavailability of, or break in access to, the Data for whatever reason. 8. You understand and acknowledge that the Data is protected by copyright and other intellectual property rights, and that duplication, except as reasonably required to carry out Your research with the Data, or sale of all or part of the Data on any media is not permitted. 9. You recognise that nothing in this agreement shall operate to transfer to the User Institution any intellectual property rights relating to the Data. The User Institution has the right to develop intellectual property based on comparisons with their own data. 10. You accept that this agreement will terminate immediately upon any breach of this agreement by You and You will be required to destroy any Data held. 11. You accept that the Data is protected by and subject to international laws, including but not limited to the UK Data Protection Act 1998, and that You are responsible for ensuring compliance with any such applicable law. The Consortium Data Access Committee reserves the right to request and inspect data security and management documentation to ensure the adequacy of data protection measures in countries that have no national laws comparable to that which pertain in the EAA. 12. This agreement shall be interpreted and construed in accordance with the laws of the country of the defending party, in cases where your Institution is the defending party, or the laws of England and Wales. Unless specified otherwise, reference in this agreement to a statute refers to that statute as it may be amended, or to any restated or successor legislation of comparable effect. Definitions Authorised Personnel: The individuals at the User Institution to whom Drs Reynolds and Duncan grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: Drs Reynolds and Duncan who are responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. Newcastle University, UK

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001005633 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005490636 fastq.gz 9.3 GB
EGAF00005490637 fastq.gz 787.1 MB
EGAF00005490638 fastq.gz 9.3 GB
EGAF00005490639 fastq.gz 7.0 GB
EGAF00005490640 fastq.gz 593.7 MB
EGAF00005490641 fastq.gz 7.1 GB
EGAF00005490642 fastq.gz 2.5 GB
EGAF00005490643 fastq.gz 590.0 MB
EGAF00005490644 fastq.gz 32.2 GB
EGAF00005490645 fastq.gz 7.3 GB
EGAF00005490646 fastq.gz 7.4 GB
EGAF00005490647 fastq.gz 2.4 GB
EGAF00005490648 fastq.gz 31.7 GB
EGAF00005490649 fastq.gz 621.3 MB
EGAF00005490650 fastq.gz 6.9 GB
EGAF00005490651 fastq.gz 7.4 GB
EGAF00005490652 fastq.gz 7.1 GB
EGAF00005490653 fastq.gz 7.4 GB
EGAF00005490654 fastq.gz 618.4 MB
EGAF00005490655 fastq.gz 9.3 GB
EGAF00005490656 fastq.gz 31.9 GB
EGAF00005490657 fastq.gz 9.2 GB
EGAF00005490658 fastq.gz 32.1 GB
EGAF00005490659 fastq.gz 782.2 MB
24 Files (231.4 GB)