Longitudinal monitoring of disease burden and response using ctDNA from dried blood spots in xenograft models

Study ID Alternative Stable ID Type
EGAS00001006134 Whole Genome Sequencing

Study Description

Study Datasets 2 datasets.

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Dataset ID Description Technology Samples
This dataset contains 8 .bam files of shallow WGS (~0.1×) from fresh frozen tumour tissues of four matched patients and first generation PDX models. Sequencing reads were aligned to the 1000 Genomes Project GRCh37-derived reference genome using the BWA aligner (v.0.07.17; CRUK-CI alignment pipeline).
Illumina HiSeq 4000 8
This dataset contains paired-end fastq sequencing files (n=212) from shallow WGS of 106 dried blood spot (DBS) samples, containing 91 DBS collected from OV04 ovarian cancer PDX mice, 10 DBS collected from healthy non-tumour bearing NSG mice, and 5 DBS generated from whole blood samples from 4 OV04 ovarian cancer patients.
Illumina NovaSeq 6000 106

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