Study

Longitudinal monitoring of disease burden and response using ctDNA from dried blood spots in xenograft models

Study ID Alternative Stable ID Type
EGAS00001006134 Whole Genome Sequencing

Study Description

Study Datasets 2 datasets.

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Dataset ID Description Technology Samples
EGAD00001008650
This dataset contains 8 .bam files of shallow WGS (~0.1×) from fresh frozen tumour tissues of four matched patients and first generation PDX models. Sequencing reads were aligned to the 1000 Genomes Project GRCh37-derived reference genome using the BWA aligner (v.0.07.17; CRUK-CI alignment pipeline).
Illumina HiSeq 4000 8
EGAD00001008651
This dataset contains paired-end fastq sequencing files (n=212) from shallow WGS of 106 dried blood spot (DBS) samples, containing 91 DBS collected from OV04 ovarian cancer PDX mice, 10 DBS collected from healthy non-tumour bearing NSG mice, and 5 DBS generated from whole blood samples from 4 OV04 ovarian cancer patients.
Illumina NovaSeq 6000 106

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