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sWGS of dried blood spots (cfDNA/ctDNA)

This dataset contains paired-end fastq sequencing files (n=212) from shallow WGS of 106 dried blood spot (DBS) samples, containing 91 DBS collected from OV04 ovarian cancer PDX mice, 10 DBS collected from healthy non-tumour bearing NSG mice, and 5 DBS generated from whole blood samples from 4 OV04 ovarian cancer patients.

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Data Access policy - Brenton and Rosenfeld Labs

Data Access Request Form – Brenton/Rosenfeld Lab, CRUK-CI, University of Cambridge, UK These terms and conditions govern access to and use of the managed access datasets to which the User Institution has requested access. The User Institution and User agree to be bound by these terms and conditions. Definitions: Confidential Information: means any information provided by the Data Provider relating to the Data Data: The managed access dataset(s) to which the User Institution has requested access, as detailed in Schedule B. Data Provider: THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE of The Old Schools, Trinity Lane, Cambridge CB2 1TN, United Kingdom and the Cambridge University Hospitals NHS Foundation Trust of Addenbrooke’s Hospital, Cambridge, CB2 0QQ; represented by staff of the Brenton and Rosenfeld Groups at the Cancer Research UK Cambridge Institute, and contactable by email at james.brenton@cruk.cam.ac.uk and nitzan.rosenfeld@cruk.cam.ac.uk or future email as updated; or future representatives as indicated in Data Access Committee(s) for the dataset(s) defined in Schedule B. Data Subject: means an individual who participated in research studies from whom the Data was derived. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Personal Data: means information and/or data about one or more living person who is the subject of personal data and who can be identified from that information, as provided under the General Data Protection Regulation (EU) 2016/679 (as amended from time to time), including but not limited to surname, initials, date of birth, address and postcodes, national insurance number, hospital number or NHS number. Project: The research project for which the User Institution has requested access to these Data, as defined in Schedule B. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. User Institution is referred to within this Agreement as “You” (and “Your” shall be construed accordingly). Data Provider will provide access to Data to the User Institution under the following Terms and Conditions: 1. You agree to preserve, at all times, the confidentiality and privacy of information and Data pertaining to Data Subjects. In particular, you undertake not to use, or attempt to use the Data to compromise or otherwise breach or infringe the confidentiality and privacy of information on Data Subjects. You agree to protect the confidentiality of Data Subjects in any Publications that you prepare by taking all reasonable care to limit the possibility of identification. You agree not to attempt to link Data to any other data source on the same samples, link the Data to any person or otherwise identify any Data Subject from the Data. 2. You agree not to transfer or disclose the Data, in whole or part, to others, except to persons within the User Institution for carrying out the Project or as reasonably necessary for Data/safety monitoring or programme management. If You wish to disclose the Data to a collaborator outside the User Institution, the third party must make a separate application for access to the Data. 3. You agree to use the Data for the advancement of medical research, and solely for the approved purpose and Project described in Schedule B and for no other purpose. 4. You agree that Data may be reissued from time to time, with suitable versioning. If the reissue is at the request of Data Subjects and/or other ethical scrutiny or concerns, you will destroy earlier versions of the Data, and upon request of Data Provider, provide written certification of such destruction. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 5. You agree to acknowledge in any Publication based in whole or part on the Data, the published paper(s) from which the Data derives, and the version of the Data. 6. You agree and acknowledge that the researchers of this study, the original Data creators, depositors, or copyright holders, and the Data Provider: a) bear no legal responsibility or liability for the accuracy or comprehensiveness of the Data, or from any use of the Data including further analysis or interpretation of such Data; and b) shall have no liability for any direct or indirect, consequential, or incidental damages or losses whatsoever arising out of Your use of the Data, or from the unavailability of, or lack of access to, the Data for whatever reason; and c) disclaim any and all representations, conditions or warranties (either express, implied or statutory) regarding the Data, including accuracy of the Data or that the Data corresponds with a particular description or is fit for a particular purpose. 7. You understand and acknowledge that the Data is owned by Data Provider and its collaborators and is protected by copyright, database rights and other intellectual property rights. You agree that you shall not reproduce or copy the Data, except as reasonably required to carry out the Project and for no other purpose, or sell all or any part of the Data in any circumstances. 8. You recognise that by granting You access to Data, no rights or ownership or intellectual property rights in or relating to the Data are transferred to You. 9. Upon any breach by You of the terms set out in this form, You will be required to destroy the Data in Your possession, and upon request, provide written certification to the Data Provider of such destruction. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 10. You accept that it may be necessary for the Data Provider to alter the terms of use of the Data from time to time. As an example, this may include specific provisions relating to the Data required by Data Provider or collaborator parties. In the event that changes are required, the Data Provider or their appointed agent will contact You to inform You of the changes and You may elect either to accept the changes or to destroy the Data in Your possession and cease its use. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 11. You agree that the Data is protected by and subject to applicable international laws. You are responsible for ensuring compliance with any such laws. The Data Provider reserves the right to request and inspect Your data security and management documentation to ensure the adequacy and compliance of data protection measures pertaining to storage and use of Data. 12. If the Data includes any identifiable Personal Data, You agree to: (a) take appropriate technical and organisational measures against the unauthorised or unlawful processing and/or use of the Data, any data derived from the Data and/or and all Confidential Information, against the accidental loss or destruction of, or damage to, such data and information. (b) ensure that the measures referred to in (a) shall include the measures set out in Schedule A. (c) restrict access to the Data, any data derived from the Data and all other Confidential Information to employees who strictly need access to such data and/or information to undertake the Project, and shall ensure that all such employees are reliable, and informed of the confidential nature of such data and/or information and the importance of processing it securely. (d) For the avoidance of doubt, You undertake not to disclose to a third party, whether in connection with the Project or otherwise, any data and/or information contained in or derived from the Data which constitutes Personal Data. Schedule A 1.1 You acknowledge and agree that the Data is pseudonymised Data and that You will become the Data Controller on receipt of such Data. 1.2 You will only process the Data for the purpose of carrying out the Project. 1.3 You agree that safeguards required under Article 89(1) of GDPR, and relevant conditions under the Data Protection Act 2018, are satisfied, and in particular that: (i) the processing of Data under or in connection with this Agreement is in the public interest; and (ii) if applicable, the Project has been subject to ethical review by an appropriate institutional review board or independent ethics committee. 1.4 The Data Provider does not intend to provide any information that may lead to You being able to identify any individual from whom any Data has been obtained. 1.5 You agree that You shall not analyse or make any use of any Data where it is reasonably foreseeable that such analysis or use may lead to the identification of any Data Subject or compromise the anonymity of any Data Subject in any way. 1.6 You shall notify the Data Provider immediately of any actual or suspected breach of security which involves the Data.  

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006134 Whole Genome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00006130548 fq.gz 234.2 MB
EGAF00006130549 fq.gz 248.5 MB
EGAF00006130550 fq.gz 739.2 MB
EGAF00006130551 fq.gz 816.8 MB
EGAF00006130552 fq.gz 651.0 MB
EGAF00006130553 fq.gz 691.6 MB
EGAF00006130554 fq.gz 464.5 MB
EGAF00006130555 fq.gz 488.4 MB
EGAF00006130556 fq.gz 458.8 MB
EGAF00006130557 fq.gz 491.7 MB
EGAF00006130558 fq.gz 567.6 MB
EGAF00006130559 fq.gz 609.8 MB
EGAF00006130560 fq.gz 514.7 MB
EGAF00006130561 fq.gz 533.6 MB
EGAF00006130562 fq.gz 684.2 MB
EGAF00006130563 fq.gz 729.5 MB
EGAF00006130564 fq.gz 754.3 MB
EGAF00006130565 fq.gz 818.3 MB
EGAF00006130566 fq.gz 1.3 GB
EGAF00006130567 fq.gz 1.3 GB
EGAF00006130568 fq.gz 253.1 MB
EGAF00006130569 fq.gz 282.2 MB
EGAF00006130570 fq.gz 1.0 GB
EGAF00006130571 fq.gz 1.1 GB
EGAF00006130572 fq.gz 1.0 GB
EGAF00006130573 fq.gz 1.1 GB
EGAF00006130574 fq.gz 333.6 MB
EGAF00006130575 fq.gz 370.6 MB
EGAF00006130576 fq.gz 731.0 MB
EGAF00006130577 fq.gz 758.6 MB
EGAF00006130578 fq.gz 778.7 MB
EGAF00006130579 fq.gz 826.5 MB
EGAF00006130580 fq.gz 2.3 GB
EGAF00006130581 fq.gz 2.3 GB
EGAF00006130582 fq.gz 925.7 MB
EGAF00006130583 fq.gz 946.9 MB
EGAF00006130584 fq.gz 1.0 GB
EGAF00006130585 fq.gz 999.8 MB
EGAF00006130586 fq.gz 1.4 GB
EGAF00006130587 fq.gz 1.5 GB
EGAF00006130588 fq.gz 1.2 GB
EGAF00006130589 fq.gz 1.2 GB
EGAF00006130590 fq.gz 1.5 GB
EGAF00006130591 fq.gz 1.6 GB
EGAF00006130592 fq.gz 274.2 MB
EGAF00006130593 fq.gz 298.5 MB
EGAF00006130594 fq.gz 250.6 MB
EGAF00006130595 fq.gz 278.0 MB
EGAF00006130596 fq.gz 298.1 MB
EGAF00006130597 fq.gz 326.2 MB
EGAF00006130598 fq.gz 869.9 MB
EGAF00006130599 fq.gz 971.9 MB
EGAF00006130600 fq.gz 635.9 MB
EGAF00006130601 fq.gz 691.4 MB
EGAF00006130602 fq.gz 377.9 MB
EGAF00006130603 fq.gz 396.9 MB
EGAF00006130604 fq.gz 645.1 MB
EGAF00006130605 fq.gz 696.3 MB
EGAF00006130606 fq.gz 243.6 MB
EGAF00006130607 fq.gz 266.3 MB
EGAF00006130608 fq.gz 498.9 MB
EGAF00006130609 fq.gz 522.2 MB
EGAF00006130610 fq.gz 2.2 GB
EGAF00006130611 fq.gz 2.2 GB
EGAF00006130612 fq.gz 4.0 GB
EGAF00006130613 fq.gz 3.9 GB
EGAF00006130614 fq.gz 915.9 MB
EGAF00006130615 fq.gz 1.0 GB
EGAF00006130616 fq.gz 1.4 GB
EGAF00006130617 fq.gz 1.5 GB
EGAF00006130618 fq.gz 670.9 MB
EGAF00006130619 fq.gz 717.1 MB
EGAF00006130620 fq.gz 869.1 MB
EGAF00006130621 fq.gz 914.0 MB
EGAF00006130622 fq.gz 817.1 MB
EGAF00006130623 fq.gz 876.4 MB
EGAF00006130624 fq.gz 830.9 MB
EGAF00006130625 fq.gz 888.1 MB
EGAF00006130626 fq.gz 1.3 GB
EGAF00006130627 fq.gz 1.3 GB
EGAF00006130628 fq.gz 1.8 GB
EGAF00006130629 fq.gz 1.8 GB
EGAF00006130630 fq.gz 1.4 GB
EGAF00006130631 fq.gz 1.4 GB
EGAF00006130632 fq.gz 254.0 MB
EGAF00006130633 fq.gz 269.9 MB
EGAF00006130634 fq.gz 318.9 MB
EGAF00006130635 fq.gz 356.8 MB
EGAF00006130636 fq.gz 680.7 MB
EGAF00006130637 fq.gz 685.0 MB
EGAF00006130638 fq.gz 256.8 MB
EGAF00006130639 fq.gz 285.6 MB
EGAF00006130640 fq.gz 333.8 MB
EGAF00006130641 fq.gz 356.9 MB
EGAF00006130642 fq.gz 585.7 MB
EGAF00006130643 fq.gz 594.8 MB
EGAF00006130644 fq.gz 309.9 MB
EGAF00006130645 fq.gz 330.1 MB
EGAF00006130646 fq.gz 281.2 MB
EGAF00006130647 fq.gz 303.0 MB
EGAF00006130648 fq.gz 235.2 MB
EGAF00006130649 fq.gz 254.3 MB
EGAF00006130650 fq.gz 754.9 MB
EGAF00006130651 fq.gz 799.1 MB
EGAF00006130652 fq.gz 626.6 MB
EGAF00006130653 fq.gz 666.3 MB
EGAF00006130654 fq.gz 584.5 MB
EGAF00006130655 fq.gz 623.2 MB
EGAF00006130656 fq.gz 675.9 MB
EGAF00006130657 fq.gz 726.1 MB
EGAF00006130658 fq.gz 647.2 MB
EGAF00006130659 fq.gz 713.4 MB
EGAF00006130660 fq.gz 968.9 MB
EGAF00006130661 fq.gz 954.6 MB
EGAF00006130662 fq.gz 311.5 MB
EGAF00006130663 fq.gz 339.2 MB
EGAF00006130664 fq.gz 327.7 MB
EGAF00006130665 fq.gz 358.3 MB
EGAF00006130666 fq.gz 1.5 GB
EGAF00006130667 fq.gz 1.5 GB
EGAF00006130668 fq.gz 1.1 GB
EGAF00006130669 fq.gz 1.2 GB
EGAF00006130670 fq.gz 525.3 MB
EGAF00006130671 fq.gz 536.7 MB
EGAF00006130672 fq.gz 296.0 MB
EGAF00006130673 fq.gz 328.2 MB
EGAF00006130674 fq.gz 838.8 MB
EGAF00006130675 fq.gz 894.6 MB
EGAF00006130676 fq.gz 618.1 MB
EGAF00006130677 fq.gz 662.2 MB
EGAF00006130678 fq.gz 475.8 MB
EGAF00006130679 fq.gz 507.8 MB
EGAF00006130680 fq.gz 607.8 MB
EGAF00006130681 fq.gz 655.8 MB
EGAF00006130682 fq.gz 864.4 MB
EGAF00006130683 fq.gz 936.1 MB
EGAF00006130684 fq.gz 930.1 MB
EGAF00006130685 fq.gz 984.1 MB
EGAF00006130686 fq.gz 968.5 MB
EGAF00006130687 fq.gz 1.0 GB
EGAF00006130688 fq.gz 1.0 GB
EGAF00006130689 fq.gz 1.1 GB
EGAF00006130690 fq.gz 225.9 MB
EGAF00006130691 fq.gz 246.0 MB
EGAF00006130692 fq.gz 277.8 MB
EGAF00006130693 fq.gz 300.0 MB
EGAF00006130694 fq.gz 347.4 MB
EGAF00006130695 fq.gz 367.7 MB
EGAF00006130696 fq.gz 637.9 MB
EGAF00006130697 fq.gz 679.7 MB
EGAF00006130698 fq.gz 267.6 MB
EGAF00006130699 fq.gz 278.2 MB
EGAF00006130700 fq.gz 288.0 MB
EGAF00006130701 fq.gz 310.7 MB
EGAF00006130702 fq.gz 476.0 MB
EGAF00006130703 fq.gz 506.3 MB
EGAF00006130704 fq.gz 692.0 MB
EGAF00006130705 fq.gz 732.1 MB
EGAF00006130706 fq.gz 1.0 GB
EGAF00006130707 fq.gz 1.2 GB
EGAF00006130708 fq.gz 1.2 GB
EGAF00006130709 fq.gz 1.2 GB
EGAF00006130710 fq.gz 660.8 MB
EGAF00006130711 fq.gz 724.2 MB
EGAF00006130712 fq.gz 782.0 MB
EGAF00006130713 fq.gz 831.7 MB
EGAF00006130714 fq.gz 232.6 MB
EGAF00006130715 fq.gz 248.8 MB
EGAF00006130716 fq.gz 579.7 MB
EGAF00006130717 fq.gz 613.3 MB
EGAF00006130718 fq.gz 475.1 MB
EGAF00006130719 fq.gz 507.7 MB
EGAF00006130720 fq.gz 732.1 MB
EGAF00006130721 fq.gz 771.9 MB
EGAF00006130722 fq.gz 734.3 MB
EGAF00006130723 fq.gz 773.9 MB
EGAF00006130724 fq.gz 471.5 MB
EGAF00006130725 fq.gz 506.7 MB
EGAF00006130726 fq.gz 903.7 MB
EGAF00006130727 fq.gz 981.4 MB
EGAF00006130728 fq.gz 860.9 MB
EGAF00006130729 fq.gz 909.1 MB
EGAF00006130730 fq.gz 983.8 MB
EGAF00006130731 fq.gz 1.1 GB
EGAF00006130732 fq.gz 715.5 MB
EGAF00006130733 fq.gz 755.2 MB
EGAF00006130734 fq.gz 714.7 MB
EGAF00006130735 fq.gz 795.5 MB
EGAF00006130736 fq.gz 791.4 MB
EGAF00006130737 fq.gz 872.0 MB
EGAF00006130738 fq.gz 750.5 MB
EGAF00006130739 fq.gz 813.3 MB
EGAF00006130740 fq.gz 812.2 MB
EGAF00006130741 fq.gz 903.9 MB
EGAF00006130742 fq.gz 698.5 MB
EGAF00006130743 fq.gz 738.0 MB
EGAF00006130744 fq.gz 944.3 MB
EGAF00006130745 fq.gz 1.0 GB
EGAF00006130746 fq.gz 521.7 MB
EGAF00006130747 fq.gz 551.6 MB
EGAF00006130748 fq.gz 1.7 GB
EGAF00006130749 fq.gz 1.8 GB
EGAF00006130750 fq.gz 330.2 MB
EGAF00006130751 fq.gz 341.7 MB
EGAF00006130752 fq.gz 285.8 MB
EGAF00006130753 fq.gz 299.5 MB
EGAF00006130754 fq.gz 826.4 MB
EGAF00006130755 fq.gz 880.5 MB
EGAF00006130756 fq.gz 364.8 MB
EGAF00006130757 fq.gz 395.0 MB
EGAF00006130758 fq.gz 647.4 MB
EGAF00006130759 fq.gz 683.7 MB
212 Files (164.2 GB)