Gremlin 1 + fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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Although cross-species transcriptional analysis has been generated for DCs, transcriptomic conservation between mouse and human FRCs at single-cell resolution has been unclear. To test whether GREM1+ FRCs might also play a role in DC homeostasis in humans, we performed scRNA-seq of CD45–PDPN+ stromal cells, as well as CD45+CD11c+ immune cells from healthy human LNs of three human donors. Data was generated using the 10x platform.
|Illumina HiSeq 4000||6|