Stromal and dendritic cells from lymph nodes: single-cell RNA-seq
Although cross-species transcriptional analysis has been generated for DCs, transcriptomic conservation between mouse and human FRCs at single-cell resolution has been unclear. To test whether GREM1+ FRCs might also play a role in DC homeostasis in humans, we performed scRNA-seq of CD45–PDPN+ stromal cells, as well as CD45+CD11c+ immune cells from healthy human LNs of three human donors. Data was generated using the 10x platform.
- 6 samples
- DAC: EGAC00001000055
- Technology: Illumina HiSeq 4000
Genentech Human LN Single-cell RNA-seq
”Human lymph node Single-cell RNA-seq was performed on sorted populations (CD45+CD11C+, CD45-PDPN+) from 3 donors”
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001006211 | Other |
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