Follicular lymphoma at diagnosis, treated in first line with immunochemotherapy

We performed targeted NGS in Follicular lymphoma samples at diagnosis. Explored clinico-genetic correlations and assessed four clinical or clinicogenetic risk models (FLIPI, FLIPI-2, PRIMA-IP or m7-FLIPI-molecular score) in patients with symptomatic FL who received frontline immunochemotherapy. Out of 191 patients with FL grade 1-3a, 109 were successfully genotyped. Treatment consisted on rituximab (R) plus CVP/CHOP (72.5%) or R-bendamustine (R-B) (27.5%).

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 1 Publication

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Dataset ID	Description	Technology	Samples
EGAD00001009647	We performed targeted NGS in Follicular lymphoma samples at diagnosis. Explored clinico-genetic correlations and assessed four clinical or clinicogenetic risk models (FLIPI, FLIPI-2, PRIMA-IP or m7-FLIPI-molecular score) in patients with symptomatic FL who received frontline immunochemotherapy. Out of 191 patients with FL grade 1-3a, 109 were successfully genotyped. Treatment consisted on rituximab (R) plus CVP/CHOP (72.5%) or R-bendamustine (R-B) (27.5%).	NextSeq 500	109

Publications	Citations
Evaluation of 4 prognostic indices in follicular lymphoma treated in first line with immunochemotherapy. Rodríguez-Sevilla JJ, Fernández-Rodríguez C, Bento L, Diez-Feijóo R, Pinzón S, Gibert J, Fernández-Ibarrondo L, Lafuente M, Ferrer A, Sánchez-González B, Gimeno E, Sainz J, Ramos R, García JF, Colomo L, Bellosillo B, Gutiérrez A, Salar A. Blood Adv 7: 2023 1606-1614	0