snRNA-seq of subcortical MS

Single-nuclei RNA-sequencing (snRNA-seq) from subcortical white matter controls and MS lesions, specifically chronic active (CA) and chronic inactive (CI), that paired with the spatial transcriptomics from the same samples, was used to identify spatial niches and key cell interactions driving inflammation and disease progression.

Type: RNASeq
Archiver: European Genome-Phenome Archive (EGA)

2 Datasets

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000000521	Dataset including FASTQ files for all snRNA-seq samples from subcortical Multiple Sclerosis (MS) lesions and controls (n=15), together with the curated and annotated snRNA-seq atlas.	Illumina NovaSeq 6000	16
EGAD50000000522	Curated subsetting of cell subtypes derived from the 9 principal cell types within our subcortical Multiple Sclerosis (MS) lesions snRNA-seq atlas.	Illumina NovaSeq 6000	16