Human colorectal cancer single-cell RNA sequencing

The aim was to investigate changes in transcriptomics following irradiation. This was studied in colorectal cancer-patient derived organoids. Analysis was performed with scRNA-seq.

Type: Transcriptome Analysis
Archiver: Federated European Genome-Phenome Archive (FEGA Finland)

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000001933	Dataset includes two scRNA-seq samples from control and irradiated organoids. Files included in the dataset are Fastq files. Sample libraries produced with Chromium X were sequenced on an Illumina NovaSeq 6000 sequencer.	Illumina NovaSeq 6000	2

Publications	Citations
A Multipotent PROX1+ Tumor Stem/Progenitor Cell Population Emerges During Intestinal Tumorigenesis and Mediates Radioresistance in Colorectal Cancer. Kallio P, Bessone C, Seyednasrollah F, Brodkin J, Lassila M, Högström J, González-Loyola A, Petrova TV, Haglund C, Alitalo K. Cancer Res 85: 2025 4616-4631	1