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Lynch syndrome adenoma and carcinoma samples

The dataset consists of high-coverage, PCR-free Whole Genome Sequencing (WGS) data (up to 100x coverage, processed via the DRAGEN pipeline) from human tissue samples. The objective is to analyze recurrent mutations and early-stage clonal evolution to identify preventative vaccine targets.

Type: Whole Genome Sequencing
Archive: European Genome-phenome Archive (EGA)

2 Datasets

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000002790	This dataset contains whole genome sequencing data from 141 Lynch syndrome adenoma samples generated at the Maruvka Laboratory, Technion – Israel Institute of Technology. Data includes WGS alignment files. Access is restricted to non-commercial scientific research purposes.		141
EGAD50000003236	Bulk RNA sequencing of 36 FFPE colorectal tissue samples from Lynch syndrome participants, including normal tissue, adenomas and carcinomas. The dataset contains GRCh37-aligned BAM files and their corresponding BAI indexes.	Illumina NovaSeq 6000	36