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Single-Cell RNA-sequencing

This dataset contains single-cell RNA-sequencing performed from CD4+ T lymphocytes and matched CRISPR/Cas9-engineered model of STAG2 wild-type and STAG2 knock-out NPM::ALK-positive cells collected at day 21 post-transfection. Libraries were performed using 10x Genomics Chromium Single Cell 5’ Kit (v2) and sequenced on Illumina NovaSeq6000 instrument.

Type: RNASeq
Archive: European Genome-phenome Archive (EGA)

1 Dataset

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000003085	Trancriptomic analyses of a CRISPR-engineered model of STAG2 wt and STAG2 KO NPM1::ALK+ cells. Bulk RNA-seq: 2 conditions (STAG2 wt NPM1::ALK+ cells vs STAG2 KO NPM1::ALK+ cells), 3 biological replicates per condition scRNA-seq: 2 conditions (WT T lymphocytes and NPM1::ALK+ cells), 2 biological replicates per condition For each sample from bulk RNA-seq: 4 fastq files (L001, L002, R1, R2) For each sample from scRNA-seq: 1 matrix file	Illumina NovaSeq 6000	10