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Transcriptome profiling of a CRISPR-engineered model of ALK+ ALCL with loss-of-function STAG2 mutations

Trancriptomic analyses of a CRISPR-engineered model of STAG2 wt and STAG2 KO NPM1::ALK+ cells. Bulk RNA-seq: 2 conditions (STAG2 wt NPM1::ALK+ cells vs STAG2 KO NPM1::ALK+ cells), 3 biological replicates per condition scRNA-seq: 2 conditions (WT T lymphocytes and NPM1::ALK+ cells), 2 biological replicates per condition For each sample from bulk RNA-seq: 4 fastq files (L001, L002, R1, R2) For each sample from scRNA-seq: 1 matrix file

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DUO:0000012
version: 2021-02-23

research specific restrictions

This data use modifier indicates that use is limited to studies of a certain research type.

DUO:0000018
version: 2021-02-23

not for profit, non commercial use only

This data use modifier indicates that use of the data is limited to not-for-profit organizations and not-for-profit use, non-commercial use.

DUO:0000025
version: 2021-02-23

time limit on use

This data use modifier indicates that use is approved for a specific number of months.

DUO:0000042
version: 2021-02-23

general research use

This data use permission indicates that use is allowed for general research use for any research purpose.

DUO:0000044
version: 2021-02-23

population origins or ancestry research prohibited

This data use modifier indicates use for purposes of population, origin, or ancestry research is prohibited.

Imagine policy

Access is granted for bona fide biomedical research consistent with informed consent and ethical approvals. Applicants must submit a research proposal, institutional endorsement, and confirmation of compliance with applicable data protection regulations. Data redistribution and re-identification attempts are strictly prohibited. A full data access request and signed data access agreement need to be submitted before gaining access to the datasets. Please contact: legal@institutimagine.org and erika.brunet@inserm.fr for the data access agreement documents.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS50000002149 RNASeq
EGAS50000002150 RNASeq

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
EGAF50001024361 fastq.gz 893.0 MB
EGAF50001024362 fastq.gz 886.4 MB
EGAF50001024363 fastq.gz 893.8 MB
EGAF50001024364 fastq.gz 887.8 MB
EGAF50001024365 fastq.gz 914.2 MB
EGAF50001024366 fastq.gz 918.1 MB
EGAF50001024367 fastq.gz 914.1 MB
EGAF50001024368 fastq.gz 918.6 MB
EGAF50001024369 fastq.gz 855.0 MB
EGAF50001024370 fastq.gz 848.1 MB
EGAF50001024371 fastq.gz 856.2 MB
EGAF50001024372 fastq.gz 849.8 MB
EGAF50001024373 fastq.gz 857.3 MB
EGAF50001024374 fastq.gz 859.4 MB
EGAF50001024375 fastq.gz 856.6 MB
EGAF50001024376 fastq.gz 859.3 MB
EGAF50001024377 fastq.gz 972.8 MB
EGAF50001024378 fastq.gz 965.9 MB
EGAF50001024379 fastq.gz 975.5 MB
EGAF50001024380 fastq.gz 969.2 MB
EGAF50001024381 fastq.gz 903.3 MB
EGAF50001024382 fastq.gz 903.8 MB
EGAF50001024383 fastq.gz 904.6 MB
EGAF50001024384 fastq.gz 905.7 MB
EGAF50001024385 h5 73.9 MB
EGAF50001024386 h5 138.0 MB
EGAF50001024387 h5 60.2 MB
EGAF50001024388 h5 63.2 MB
28 Files (21.9 GB)