Transcriptome profiling of a CRISPR-engineered model of ALK+ ALCL with loss-of-function STAG2 mutations
Trancriptomic analyses of a CRISPR-engineered model of STAG2 wt and STAG2 KO NPM1::ALK+ cells. Bulk RNA-seq: 2 conditions (STAG2 wt NPM1::ALK+ cells vs STAG2 KO NPM1::ALK+ cells), 3 biological replicates per condition scRNA-seq: 2 conditions (WT T lymphocytes and NPM1::ALK+ cells), 2 biological replicates per condition For each sample from bulk RNA-seq: 4 fastq files (L001, L002, R1, R2) For each sample from scRNA-seq: 1 matrix file
- 10/11/2026
- 10 samples
- DAC: EGAC50000000951
- Technology: Illumina NovaSeq 6000
- Archive: European Genome-phenome Archive (EGA)
DUO:0000012 version: 2021-02-23
research specific restrictions
This data use modifier indicates that use is limited to studies of a certain research type.
DUO:0000018 version: 2021-02-23
not for profit, non commercial use only
This data use modifier indicates that use of the data is limited to not-for-profit organizations and not-for-profit use, non-commercial use.
DUO:0000025 version: 2021-02-23
time limit on use
This data use modifier indicates that use is approved for a specific number of months.
DUO:0000042 version: 2021-02-23
general research use
This data use permission indicates that use is allowed for general research use for any research purpose.
DUO:0000044 version: 2021-02-23
population origins or ancestry research prohibited
This data use modifier indicates use for purposes of population, origin, or ancestry research is prohibited.
Imagine policy
Access is granted for bona fide biomedical research consistent with informed consent and ethical approvals. Applicants must submit a research proposal, institutional endorsement, and confirmation of compliance with applicable data protection regulations. Data redistribution and re-identification attempts are strictly prohibited. A full data access request and signed data access agreement need to be submitted before gaining access to the datasets. Please contact: legal@institutimagine.org and erika.brunet@inserm.fr for the data access agreement documents.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000002149 | RNASeq | |
| EGAS50000002150 | RNASeq |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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| EGAF50001024361 | fastq.gz | 893.0 MB |
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| EGAF50001024362 | fastq.gz | 886.4 MB |
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| EGAF50001024363 | fastq.gz | 893.8 MB |
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| EGAF50001024364 | fastq.gz | 887.8 MB |
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| EGAF50001024365 | fastq.gz | 914.2 MB |
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| EGAF50001024366 | fastq.gz | 918.1 MB |
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| EGAF50001024367 | fastq.gz | 914.1 MB |
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| EGAF50001024368 | fastq.gz | 918.6 MB |
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| EGAF50001024369 | fastq.gz | 855.0 MB |
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| EGAF50001024370 | fastq.gz | 848.1 MB |
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| EGAF50001024371 | fastq.gz | 856.2 MB |
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| EGAF50001024372 | fastq.gz | 849.8 MB |
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| EGAF50001024373 | fastq.gz | 857.3 MB |
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| EGAF50001024374 | fastq.gz | 859.4 MB |
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| EGAF50001024375 | fastq.gz | 856.6 MB |
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| EGAF50001024376 | fastq.gz | 859.3 MB |
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| EGAF50001024377 | fastq.gz | 972.8 MB |
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| EGAF50001024378 | fastq.gz | 965.9 MB |
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| EGAF50001024379 | fastq.gz | 975.5 MB |
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| EGAF50001024380 | fastq.gz | 969.2 MB |
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| EGAF50001024381 | fastq.gz | 903.3 MB |
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| EGAF50001024382 | fastq.gz | 903.8 MB |
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| EGAF50001024383 | fastq.gz | 904.6 MB |
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| EGAF50001024384 | fastq.gz | 905.7 MB |
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| EGAF50001024385 | h5 | 73.9 MB |
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| EGAF50001024386 | h5 | 138.0 MB |
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| EGAF50001024387 | h5 | 60.2 MB |
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| EGAF50001024388 | h5 | 63.2 MB |
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| 28 Files (21.9 GB) | ||||
