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Multimodal Study of Malignant Rhabdoid Tumors

Original Manuscript Title: "MET inhibition exploits conserved regulatory dependencies in malignant rhabdoid tumors" | Single-cell multi-omic profiling (Chromium Single Cell Multiome ATAC + Gene Expression, 10X Genomics, n=16 patients) and spatial transcriptomics across anatomically and molecularly diverse malignant rhabdoid tumors (Visium, 10X Genomics, n=11 patients).

Type: Transcriptome Sequencing
Archive: European Genome-phenome Archive (EGA)

2 Datasets

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000003171	Raw sequencing data (FASTQ) from 16 patients with malignant rhabdoid tumours (9 ERRT, 5 ATRT, 2 KRT), generated with the 10x Genomics Chromium Single Cell Multiome ATAC + Gene Expression kit. Each patient sample has a gene expression library and an ATAC library from the same nuclei. ATAC runs include read 1, read 2 and the cell-barcode read (UMI2).	Illumina NovaSeq 6000	16
EGAD50000003172	Raw sequencing data (FASTQ) from fresh-frozen tumour sections of 11 patients with malignant rhabdoid tumours (5 ERRT, 4 ATRT, 2 KRT), generated with 10x Genomics Visium Spatial Gene Expression v1 (3').	Illumina NovaSeq 6000	11