Data Access Committee for Institut Curie

Dac ID Contact Person Email Access Information
EGAC00001000670 Xosé M Fernández data [dot] office [at] curie [dot] fr No additional information is available

This DAC controls 3 datasets:

Dataset ID Description Technology Samples
EGAD00001003930 Whole Exome Sequencing Illumina HiSeq 2500 6
EGAD00001004554 Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Despite improvement of diagnosis and treatment of the primary tumor, there is no effective treatment of metastatic disease and approximately half of patients will die within one year or less following metastases detection. Tumor heterogeneity has been proposed as a key factor of drug resistance. However, it has been scarcely studied in UM. The present project aims searching for specific drivers of the metastatic progression, describing the genomic and transcriptomic landscape of metastatic UM, exploring tumor heterogeneity and investigating its role in drug resistance. Thus whole exome sequencing and transcriptomics have been performed on constitutional, primary tumor and metastatic samples from 28 UM patients. Illumina HiSeq 2500 110
EGAD00010001463 Genotype cases using Illumina HumanOmni5 Illumina HumanOmni5 279