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DAC for Greenland Studies of University of Copenhagen and University of Southern Denmark.

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Christina Viskum Lytken Larsen
cll@si-folkesundhed.dk

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This DAC controls 9 datasets

Dataset ID	Description	Technology	Samples
EGAD00001003813	The data contain whole exome sequencing of 27 Greenlanders in nine trios. Data were produced by Agilent SureSelect capture followed by paired-end Illumina HiSeq 2000 sequencing to a depth of 90.1X. More details on processing and analysis can be found in Moltke et al, Nature 2014 (PMID 25043022).	Illumina HiSeq 2000	27
EGAD00001003814	The data contain whole deep RNA sequencing of leukocytes from 17 Greenlanders. RNA was purified from peripheral blood with the PAXGene Blood miRNA Kit (Qiagen). The RNA sequencing library was prepared following the instructions of the TruSeq RNA Sample Prep Kit v2 (Illumina). For mRNA isolation and fragmentation 200 ng of total RNA was purified by oligo-dT beads. The qualified libraries were amplified on cBot to generate the cluster on the flowcell (TruSeq PE Cluster Kit V3–cBot–HS, Illumina). The amplified flow cell was sequenced paired-end on the HiSeq 4000 System (TruSeq SBS KIT-HS V3, Illumina).	Illumina HiSeq 4000	17
EGAD00001007717	The data contain whole transcriptome sequencing of 499 Greenlanders.	unspecified	499
EGAD00010001427	Cardio-Metabochip genotypes for B99 cohort	Illumina	1336
EGAD00010001428	Cardio-Metabochip genotypes for IHIT cohort	Illumina	2791
EGAD00010002057	This file fileset has 4607 Greenlanders scored on the Illumina MEGA array (1,622,813 sites), and has been put on the plus strand. The data is in PLINK bed/bim/fam format. The Greenlandic individuals originate from two population surveys, B99 and IHIT.	Illumina MEGA array	4607
EGAD50000000059	Skeletal muscle of Inuit homozygous carriers of the common Greenlandic TBC1D4 p.Arg684Ter variant is severely insulin resistant but have normal metabolic responses during exercise	Illumina HiSeq 4000	58
EGAD50000000933	This file set has 448 Greenlandic individuals sequenced using Illumina 150 Paired end sequencing and has an average sequencing depth of 35X. The data is unfiltered, in VCF format, and covers 19.751.308 variants.		448
EGAD50000000934	This file set has 1478 Greenlandic individuals scored on the Illumina MEGA array (1,748,250 sites). The data is in PLINK bed/bim/fam format. The individuals originate from the B2018 population survey.		1478