DAC
The evolutionary history of human colitis-associated colorectal cancer
| Dac ID | Contact Person | Access Information | |
|---|---|---|---|
| EGAC00001000917 | Trevor Graham | t [dot] graham [at] qmul [dot] ac [dot] uk | No additional information is available |
This DAC controls 5 datasets:
| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD00001004270 | Genome-wide copy number profiling was performed using low-pass whole genome sequencing on archival non-dysplastic mucosa (n=9), low-grade dysplasia (LGD; n=30), high-grade dysplasia (HGD; n=13), mixed LGD/HGD (n=7) and CA-CRC (n=19). | Illumina NovaSeq 6000 | 81 |
| EGAD00001004275 | Exome sequencing was performed on fresh-frozen multiple regions of carcinoma, adjacent non-cancerous mucosa and blood from 12 CA-CRC patients (n=55 exomes). | Illumina Genome Analyzer II | 64 |
| EGAD00001004966 | Dataset of adenoma and colon cancer multi-region sequencing. Publication: Nat Ecol Evol. 2018 Oct;2(10):1661-1672. doi: 10.1038/s41559-018-0642-z. Epub 2018 Aug 31. | Illumina HiSeq 2500,unspecified | 139 |
| EGAD00010001586 | This data set contains an .Rdata file for all the processed segmentation profiles from 81 lpWGS samples included used in downstream analyses from Github repository Evo_history_CACRC. Lastly, there is an .Rdata object with 50 segmentations for 50 total samples from 25 sporadic SNP adenomas used in the comparison with colitis samples. | Low Pass Whole Genome Sequencing (LP-WGS) | 131 |
| EGAD00010001587 | This dataset contains 30 idat files each from 15 SNP array runs on patient colitis-associated colorectal cancer tumours. All phenotypes are cancer. See Baker et al. 2018 Supplementary Table 2 for patient details of 12 tumours used in the analyses in the publication. | SNP array | 15 |
