DAC

MOMA - Bladder group DAC

Dac ID Contact Person Email Access Information
EGAC00001001642 Lars Dyrskjøt lars [at] clin [dot] au [dot] dk No additional information is available

This DAC controls 7 datasets:

Dataset ID Description Technology Samples
EGAD00001006238 In this study, a total of 300 patients with MIBC receiving chemotherapy were included; 62 received NAC before cystectomy and 245 received first-line chemotherapy upon detection of locally-advanced (T4b) or metastatic disease. Treatment response, defined as pathological downstaging (< pTa,CIS,N0) after NAC or complete or partial response after first-line treatment (RECIST criteria). RNA-seq was performed using the QuantSeq kit FWD HT kit (Lexogen) using 500 ng input RNA from 121 tumor samples. Data provided here consist of 780 fastq files for RNA-seq. NextSeq 500 121
EGAD00001006239 In this study, a total of 300 patients with MIBC receiving chemotherapy were included; 62 received NAC before cystectomy and 245 received first-line chemotherapy upon detection of locally-advanced (T4b) or metastatic disease. Treatment response, defined as pathological downstaging (< pTa,CIS,N0) after NAC or complete or partial response after first-line treatment (RECIST criteria). WES was performed using DNA from 165 tumors (76x median coverage) and associated germline DNA (46x median coverage). Data provided here consist of 5,828 fastq files for WES. Illumina NovaSeq 6000,NextSeq 500 330
EGAD00001006656 For this project about non-muscle invasive bladder cancer (NMIBC), we analysed total RNA-seq data from 535 patients. Sequencing of total RNA was performed using ScriptSeq-v2 RNA-Seq Library Preparation Kit (Illumina) and KAPA RNA HyperPrep Kit with RiboErase HMR (Roche). RNA input was 500 ng for both kits. The dataset is composed of 1,596 fastq files. Illumina HiSeq 2000,Illumina MiSeq,Illumina NovaSeq 6000,NextSeq 550 535
EGAD00010001921 EPIC array data from 72 tumor samples with muscle invasive bladder cancer. EPIC BeadChip (Illumina, San Diego, CA) 72
EGAD00010001943 SNP data from 49 paired samples (tumor/germline) with muscle invasive bladder cancer. Illumina Infinium Human Global Screening Array GSAMD-24v2-0_20024620_a1 BeadChip 98
EGAD00010002038 SNP data for 473 tumor samples Illumina Infinium Human Global Screening Array GSAMD-24v2-0_20024620_a1 BeadChip 473
EGAD00010002039 SNP data for 473 germline samples Illumina Infinium OncoArray-500K 473