DAC
Charite Berlin Paediatric Oncology Data Access Committee
Dac ID | Contact Person | Access Information | |
---|---|---|---|
EGAC00001001766 | Angelika Eggert | angelika [dot] eggert [at] charite [dot] de | No additional information is available |
This DAC controls 4 datasets:
Dataset ID | Description | Technology | Samples |
---|---|---|---|
EGAD00001008020 | To investigate intratumour heterogeneity and to better understand tumour evolution in neuroblastoma, we have performed a multi-region whole-exome sequencing on a total of 51 spatially separated tumor samples from 9 primary neuroblastomas (2 low-risk, 1 intermediate-risk and 6 high-risk) and 1 relapsed neuroblastoma. We also assessed the impact of chemotherapy on the clonal expansion by sequencing tumour regions from one medium risk and one high-risk tumour for which we had matched samples obtained at diagnosis and after chemotherapy. | Illumina HiSeq 4000 | 61 |
EGAD00001008133 | To investigate intratumour heterogeneity and to better understand tumour evolution in neuroblastoma, we have performed a multi-region RNA sequencing on a total of 51 spatially separated tumor samples from 9 primary neuroblastomas (2 low-risk, 1 intermediate-risk and 6 high-risk) and 1 relapsed neuroblastoma. We also assessed the impact of chemotherapy on the clonal expansion by sequencing tumour regions from one medium risk and one high-risk tumour for which we had matched samples obtained at diagnosis and after chemotherapy. | Illumina HiSeq 4000 | 50 |
EGAD00001008156 | To investigate intratumour heterogeneity and to better understand tumour evolution in neuroblastoma, we have performed a multi-region targeted re-sequencing on a total of 140 samples from 9 primary neuroblastomas (2 low-risk, 1 intermediate-risk and 6 high-risk) and 2 relapsed neuroblastoma. | Illumina HiSeq 4000 | 141 |
EGAD00010002225 | SNP Array from CB1003 using Cytoscan HD, Thermo Fisher Scientific | Cytoscan HD | 3 |