Dataset

Multi-region sequencing of 10 neuroblastoma cases

Dataset ID Technology Samples
EGAD00001008020 Illumina HiSeq 4000 61

Dataset Description

To investigate intratumour heterogeneity and to better understand tumour evolution in neuroblastoma, we have performed a multi-region whole-exome sequencing on a total of 51 spatially separated tumor samples from 9 primary neuroblastomas (2 low-risk, 1 intermediate-risk and 6 high-risk) and 1 relapsed neuroblastoma. We also assessed the impact of chemotherapy on the clonal expansion by sequencing tumour regions from one medium risk and one high-risk tumour for which we had matched samples obtained at diagnosis and after chemotherapy.

Who controls access to this dataset

For each dataset that requires controlled access, there is a corresponding Data Access Committee (DAC) who determine access permissions. Access to actual data files is not managed by the EGA. If you need to request access to this data set, please contact:

Charite Berlin Paediatric Oncology Data Access Committee
Contact person: Angelika Eggert
Email: angelika [dot] eggert [at] charite [dot] de
More details: EGAC00001001766

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