COMET TCRseq Data Access Commitee

Kjersti K Flatmark
kjersti.flatmark@rr-research.no

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Dataset ID	Description	Technology	Samples
EGAD00001010269	This is the raw TCRseq data for the manuscript T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases.	NextSeq 500	8
EGAD50000000926	Metastatic colorectal cancer (mCRC) is the main cause of CRC mortality, with limited treatment options. Although immunotherapy has benefited some cancer patients, mCRC typically lacks the molecular features that respond to this treatment. However, recent studies indicate that the immune microenvironment of mCRC may be modified to enhance the effect of immune checkpoint inhibitors. This dataset was used to explore the metastatic immune microenvironment by comparing immune cell populations in colorectal liver (CLM), lung (mLu) and peritoneal (PM) metastases.	Illumina NovaSeq 6000	40