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DAC UMR Inserm U1236

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Simon sleonard
simon.leonard@univ-rennes.fr

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This DAC controls 7 datasets

Dataset ID	Description	Technology	Samples
EGAD50000000471	The impact of MSC(UC) on peripheral B cells from Systemic Lupus Erythematosus (SLE) patients was studied by 10X scRNAseq. This scRNAseq study encompassed 3 SLE patients at 3 time points: before or after (1 month, and 3 months) MSC injection in order to analyze B cell subsets and their DEG. The aim of this study was to observe the potential changes of B cell subsets after MSC(UC) injection in SLE patients.	Illumina NovaSeq X	3
EGAD50000001242	LAM-HTGTS dataset after DIS3 ASO or Control ASO treatment on human cells under plasmablast differentiation.	Illumina MiSeq	8
EGAD50000001243	RNAseq experiment after DIS3 ASO or Control ASO treatment on human cells under plasmablast differentiation.	Illumina NovaSeq 6000	26
EGAD50000001529	scRNAseq dataset of circulating T cells from 3 FL patients (P011, P014 and P020) included in the GALEN clinical trial. There is two time points for each patient : One before treatment (D0) and one at day 7 of Lenalidomide treatment (D7).	Illumina NovaSeq 6000	6
EGAD50000001601	This dataset contains BCR sequences of buffy coat purified B-cells from 5 healthy donors. For each sample, sequences were obtained in two conditions : with control Aso and Dis Aso treatment.	NextSeq 2000	10
EGAD50000001629	This dataset contains fastq files from scRNAseq dataset of myeloid cells from secondary lymphoid organs (lymph nodes and tonsil) from lymphoma patients (3 FL and 3 DLBCL) and controls (3 reactive tonsils and 3 reactive lymph nodes). For HTO libraries, demultiplexing barcodes are available in samples descriptions.	Illumina NovaSeq 6000	8
EGAD50000001843	This dataset contains transcriptome, BCR, TCR and HTO data at the single cell level from follicular lymphoma bone marrow samples at diagnosis (n=19) and one year post rituximab therapy (n=16).	Illumina HiSeq 2000	39