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The Transcriptome of PLX4032 resistance

We have collected material from a patient who had BrafV600E mutant melanoma that was treated with PLX4032. We have germline DNA from the patient and DNA and RNA from distinct lesions before and after treatment with PLX4032. We have transcriptome sequenced these samples to obtain a snap shot of the mechanisms of resistance that are operative.

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001000413 Transcriptome Analysis

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00000188566 bam 230.0 MB
EGAF00000188567 bam 257.0 MB
EGAF00000188568 bam 274.5 MB
EGAF00000188569 bam 330.6 MB
EGAF00000188570 bam 322.9 MB
EGAF00000188571 bam 251.1 MB
EGAF00000188572 bam 228.9 MB
EGAF00000188573 bam 255.9 MB
EGAF00000188574 bam 272.8 MB
EGAF00000188575 bam 328.9 MB
EGAF00000188576 bam 321.8 MB
EGAF00000188577 bam 249.8 MB
12 Files (3.3 GB)