About file location

As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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Raw sequencing data - Intra-tumor heterogeneity and clonal evolution patterns towards platinum-resistant high-grade serous ovarian cancer

This dataset includes 69 sampels of whole-exome sequencing data of high-grade serous ovarian carcinoma (HGSOC). We included patients with advanced (International Federation of Gynecology and bstetrics [FIGO] stage IIIeIV) HGSOC for which biopsies were obtained during debulking surgery, the first at initial diagnosis and the second at disease relapse. Where possible, matched normal DNA from each participating patient was obtained from a whole-blood sample. Written informed consent was obtained from all patients and approved by the local ethics committee.

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VIB_VRC Data Access Policy

VIB and Recipient agree as follows:1.VIB shall remain the sole owner of the Data.2.Recipient shall utilise the Data only to conduct the Research. Nothing in this Agreement shall be deemed to grant Recipient any rights under any intellectual property rights owned or controlled by VIB, nor any rights to use the Data for purposes other than to conduct the Research. Without limitation to the generality of the above, no right whatsoever is granted to Recipient for commercial use of the Data. Use of the Data for a new purpose will require a new application and approval.3.Recipient undertakes to limit access to the Data to those of its employees working directly under the supervision of the Recipient Investigator who need to have access to the Data to execute the Research. Recipient undertakes to have any of its personnel involved in the Research comply with the provisions of this agreement. Should the Recipient wish to share the Data with a collaborator, said collaborator must make a separate application for access to Data.4.Recipient undertakes to keep personal data pertaining to data subjects, including, but not limited to information as to (a) the racial or ethnic origin of the data subject, (b) his/her political opinions, (c) his/her religious beliefs or other beliefs of a similar nature, (d) his/her physical or mental health or condition, (e) his/her sexual life, (f) the commission or alleged commission by him/her of any offence, or (g) any proceedings for any offence committed or alleged to have been committed by him/her, the disposal of such proceedings or the sentence of any court in such proceedings (hereinafter Sensitive Personal Information”), strictly confidential and not to disclose Sensitive Personal Information or use the Sensitive Personal Information for any other purpose than to conduct the Research.5.VIB does not warrant that the use of the Data does not or will not infringe any patent. VIB is under no obligation to obtain or provide licenses that may be required for the use of the Data by the Recipient.6.In consideration of VIB providing the Data, Recipient agrees to promptly inform VIB, in confidence, of any invention or development, whether patentable or not, conceived or reduced to practice by Recipient through the use of the Data (“Developments”). Recipient will, on the request of VIB, submit a written report upon the completion of the Research to VIB. VIB shall treat said report confidential.7.Ownership of Developments will be negotiated in good faith between Recipient and VIB, hereto depending upon the parties’ relative contribution to the Developments, including the relative contribution of the Data to the creation of the Developments, and any applicable law and regulations relating to inventorship.8.Recipient will not obtain and will not attempt to obtain patent coverage on the Data or Developments or on any use of the Data or Developments, without first notifying VIB, so that VIB can assert any claims to inventorship it or its researchers may have.9.Recipient grants to VIB an irrevocable royalty-free non-exclusive license to use such Developments for VIB’s internal research purposes and will negotiate in good faith, based on each party’s relative contribution, including the relative contribution of the Data to the creation of the Developments, the sharing of revenues derived from the licensing, sale, or commercialisation of any such Developments.10.Recipient will have the right to publish and disclose the results of the Research. In order to balance this with VIB’s proprietary interests, Recipient will submit the intended disclosure (e.g. a manuscript, abstract, patent application, poster, etc) to VIB for review at least thirty (30) days prior to the scheduled disclosure date. VIB may within this 30 day period request Recipient, in writing, to delete any reference to VIB’s Confidential Data apart from Data and/or to delay the intended disclosure for a maximum of an additional ninety (90) days. Recipient agrees to provide appropriate acknowledgement of the source of the Data in any publication and presentation based on the use of the Data.11.Recipient will use the Data in compliance with all laws and regulations both nationally and internationally.. The Data is provided by VIB “as is”, with no warranties, express or implied, including any warranty of accuracy, completeness, merchantability, title, or fitness for a particular use. Recipient will indemnify VIB and hold VIB harmless from any claims or liabilities which might arise as a result of Recipient’s use of the Data, unless such claims or liabilities are caused by VIB’s gross negligence or malicious intent.12.This Agreement will be governed and interpreted in accordance with the Belgian law.To confirm agreement with the above terms, please have an authorised representative sign and date the agreement below. The signature of the investigator is optional. WHEN SUBMITTING THIS DOCUMENT, PLEASE INCLUDE ALL PAGES OF THE AGREEMENT WITH THIS SIGNATURE PAGE. Please return both originals to Jan Staelens, VIB, Rijvisschestraat 120, B - 9052 Zwijnaarde, Belgium. We will return one fully executed agreement to Recipient. Please indicate in your accompanying letter the responsible person (with address) to whom we have to send the Data.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001001244 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF00000825419 fastq.gz 3.0 GB Report
EGAF00000825420 fastq.gz 3.1 GB Report
EGAF00000825421 fastq.gz 2.7 GB Report
EGAF00000825422 fastq.gz 2.8 GB Report
EGAF00000825423 fastq.gz 2.3 GB Report
EGAF00000825424 fastq.gz 2.4 GB Report
EGAF00000825425 fastq.gz 1.4 GB Report
EGAF00000825426 fastq.gz 1.4 GB Report
EGAF00000825427 fastq.gz 6.7 GB Report
EGAF00000825428 fastq.gz 6.8 GB Report
EGAF00000825429 fastq.gz 901.9 MB Report
EGAF00000825430 fastq.gz 880.0 MB Report
EGAF00000825431 fastq.gz 938.9 MB Report
EGAF00000825432 fastq.gz 883.2 MB Report
EGAF00000825433 fastq.gz 883.3 MB Report
EGAF00000825434 fastq.gz 873.6 MB Report
EGAF00000825435 fastq.gz 2.6 GB Report
EGAF00000825436 fastq.gz 2.6 GB Report
EGAF00000825437 fastq.gz 2.4 GB Report
EGAF00000825438 fastq.gz 2.5 GB Report
EGAF00000825439 fastq.gz 5.2 GB Report
EGAF00000825440 fastq.gz 5.1 GB Report
EGAF00000825441 fastq.gz 2.8 GB Report
EGAF00000825442 fastq.gz 2.9 GB Report
EGAF00000825443 fastq.gz 1.1 GB Report
EGAF00000825444 fastq.gz 1.1 GB Report
EGAF00000825445 fastq.gz 4.8 GB Report
EGAF00000825446 fastq.gz 4.8 GB Report
EGAF00000825447 fastq.gz 4.3 GB Report
EGAF00000825448 fastq.gz 4.3 GB Report
EGAF00000825449 fastq.gz 3.0 GB Report
EGAF00000825450 fastq.gz 3.0 GB Report
EGAF00000825451 fastq.gz 2.9 GB Report
EGAF00000825452 fastq.gz 2.9 GB Report
EGAF00000825453 fastq.gz 2.5 GB Report
EGAF00000825454 fastq.gz 2.5 GB Report
EGAF00000825455 fastq.gz 1.2 GB Report
EGAF00000825456 fastq.gz 1.1 GB Report
EGAF00000825457 fastq.gz 2.0 GB Report
EGAF00000825458 fastq.gz 2.0 GB Report
EGAF00000825459 fastq.gz 1.9 GB Report
EGAF00000825460 fastq.gz 1.9 GB Report
EGAF00000825461 fastq.gz 2.2 GB Report
EGAF00000825462 fastq.gz 2.2 GB Report
EGAF00000825463 fastq.gz 2.3 GB Report
EGAF00000825464 fastq.gz 2.3 GB Report
EGAF00000825465 fastq.gz 2.1 GB Report
EGAF00000825466 fastq.gz 2.1 GB Report
EGAF00000825467 fastq.gz 6.5 GB Report
EGAF00000825468 fastq.gz 6.6 GB Report
EGAF00000825469 fastq.gz 2.4 GB Report
EGAF00000825470 fastq.gz 2.5 GB Report
EGAF00000825471 fastq.gz 1.8 GB Report
EGAF00000825472 fastq.gz 1.7 GB Report
EGAF00000825473 fastq.gz 1.9 GB Report
EGAF00000825474 fastq.gz 1.9 GB Report
EGAF00000825475 fastq.gz 1.1 GB Report
EGAF00000825476 fastq.gz 1.1 GB Report
EGAF00000825477 fastq.gz 1.2 GB Report
EGAF00000825478 fastq.gz 1.2 GB Report
EGAF00000825479 fastq.gz 1.2 GB Report
EGAF00000825480 fastq.gz 1.1 GB Report
EGAF00000825481 fastq.gz 3.6 GB Report
EGAF00000825482 fastq.gz 3.6 GB Report
EGAF00000825483 fastq.gz 2.9 GB Report
EGAF00000825484 fastq.gz 2.9 GB Report
EGAF00000825485 fastq.gz 2.3 GB Report
EGAF00000825486 fastq.gz 2.3 GB Report
EGAF00000825487 fastq.gz 2.8 GB Report
EGAF00000825488 fastq.gz 2.8 GB Report
EGAF00000825489 fastq.gz 3.3 GB Report
EGAF00000825490 fastq.gz 3.4 GB Report
EGAF00000825491 fastq.gz 2.6 GB Report
EGAF00000825492 fastq.gz 2.7 GB Report
EGAF00000825493 fastq.gz 2.6 GB Report
EGAF00000825494 fastq.gz 2.6 GB Report
EGAF00000825495 fastq.gz 1.7 GB Report
EGAF00000825496 fastq.gz 1.7 GB Report
EGAF00000825497 fastq.gz 1.4 GB Report
EGAF00000825498 fastq.gz 1.4 GB Report
EGAF00000825499 fastq.gz 8.7 GB Report
EGAF00000825500 fastq.gz 8.6 GB Report
EGAF00000825501 fastq.gz 6.5 GB Report
EGAF00000825502 fastq.gz 6.4 GB Report
EGAF00000825503 fastq.gz 3.2 GB Report
EGAF00000825504 fastq.gz 3.2 GB Report
EGAF00000825505 fastq.gz 3.0 GB Report
EGAF00000825506 fastq.gz 3.0 GB Report
EGAF00000825507 fastq.gz 2.9 GB Report
EGAF00000825508 fastq.gz 2.9 GB Report
EGAF00000825509 fastq.gz 5.5 GB Report
EGAF00000825510 fastq.gz 5.4 GB Report
EGAF00000825511 fastq.gz 1.3 GB Report
EGAF00000825512 fastq.gz 1.3 GB Report
EGAF00000825513 fastq.gz 1.9 GB Report
EGAF00000825514 fastq.gz 1.9 GB Report
EGAF00000825515 fastq.gz 1.7 GB Report
EGAF00000825516 fastq.gz 1.7 GB Report
EGAF00000825517 fastq.gz 5.4 GB Report
EGAF00000825518 fastq.gz 5.4 GB Report
EGAF00000825519 fastq.gz 4.6 GB Report
EGAF00000825520 fastq.gz 4.5 GB Report
EGAF00000825521 fastq.gz 609.2 MB Report
EGAF00000825522 fastq.gz 611.4 MB Report
EGAF00000825523 fastq.gz 1.8 GB Report
EGAF00000825524 fastq.gz 1.8 GB Report
EGAF00000825525 fastq.gz 4.9 GB Report
EGAF00000825526 fastq.gz 4.9 GB Report
EGAF00000825527 fastq.gz 5.2 GB Report
EGAF00000825528 fastq.gz 5.3 GB Report
EGAF00000825529 fastq.gz 2.1 GB Report
EGAF00000825530 fastq.gz 2.1 GB Report
EGAF00000825531 fastq.gz 1.1 GB Report
EGAF00000825532 fastq.gz 1.1 GB Report
EGAF00000825533 fastq.gz 4.4 GB Report
EGAF00000825534 fastq.gz 4.4 GB Report
EGAF00000825535 fastq.gz 3.5 GB Report
EGAF00000825536 fastq.gz 3.5 GB Report
EGAF00000825537 fastq.gz 1.2 GB Report
EGAF00000825538 fastq.gz 1.2 GB Report
EGAF00000825539 fastq.gz 2.8 GB Report
EGAF00000825540 fastq.gz 2.9 GB Report
EGAF00000825541 fastq.gz 3.7 GB Report
EGAF00000825542 fastq.gz 3.7 GB Report
EGAF00000825543 fastq.gz 2.8 GB Report
EGAF00000825544 fastq.gz 2.8 GB Report
EGAF00000825545 fastq.gz 1.6 GB Report
EGAF00000825546 fastq.gz 1.6 GB Report
EGAF00000825547 fastq.gz 2.3 GB Report
EGAF00000825548 fastq.gz 2.3 GB Report
EGAF00000825549 fastq.gz 2.0 GB Report
EGAF00000825550 fastq.gz 2.0 GB Report
EGAF00000825551 fastq.gz 1.5 GB Report
EGAF00000825552 fastq.gz 1.5 GB Report
EGAF00000825553 fastq.gz 6.4 GB Report
EGAF00000825554 fastq.gz 6.4 GB Report
EGAF00000825555 fastq.gz 3.0 GB Report
EGAF00000825556 fastq.gz 3.0 GB Report
EGAF00000825557 fastq.gz 3.8 GB Report
EGAF00000825558 fastq.gz 3.9 GB Report
EGAF00000825559 fastq.gz 2.9 GB Report
EGAF00000825560 fastq.gz 2.9 GB Report
EGAF00000825561 fastq.gz 2.8 GB Report
EGAF00000825562 fastq.gz 2.8 GB Report
EGAF00000825563 fastq.gz 1.7 GB Report
EGAF00000825564 fastq.gz 1.6 GB Report
EGAF00000825565 fastq.gz 1.7 GB Report
EGAF00000825566 fastq.gz 1.6 GB Report
EGAF00000825567 fastq.gz 2.0 GB Report
EGAF00000825568 fastq.gz 2.0 GB Report
EGAF00000825569 fastq.gz 2.8 GB Report
EGAF00000825570 fastq.gz 2.8 GB Report
EGAF00000825571 fastq.gz 2.6 GB Report
EGAF00000825572 fastq.gz 2.6 GB Report
EGAF00000825573 fastq.gz 2.5 GB Report
EGAF00000825574 fastq.gz 2.6 GB Report
EGAF00000825575 fastq.gz 3.4 GB Report
EGAF00000825576 fastq.gz 3.4 GB Report
EGAF00000825577 fastq.gz 2.4 GB Report
EGAF00000825578 fastq.gz 2.5 GB Report
EGAF00000825579 fastq.gz 2.7 GB Report
EGAF00000825580 fastq.gz 2.8 GB Report
EGAF00000825581 fastq.gz 2.3 GB Report
EGAF00000825582 fastq.gz 2.3 GB Report
EGAF00000825583 fastq.gz 3.1 GB Report
EGAF00000825584 fastq.gz 3.2 GB Report
EGAF00000825585 fastq.gz 3.3 GB Report
EGAF00000825586 fastq.gz 3.3 GB Report
EGAF00000825587 fastq.gz 1.2 GB Report
EGAF00000825588 fastq.gz 1.1 GB Report
EGAF00000825589 fastq.gz 1.3 GB Report
EGAF00000825590 fastq.gz 1.3 GB Report
EGAF00000825591 fastq.gz 1.3 GB Report
EGAF00000825592 fastq.gz 1.2 GB Report
EGAF00000825593 fastq.gz 1.3 GB Report
EGAF00000825594 fastq.gz 1.2 GB Report
EGAF00000825595 fastq.gz 1.7 GB Report
EGAF00000825596 fastq.gz 1.7 GB Report
EGAF00000825597 fastq.gz 2.9 GB Report
EGAF00000825598 fastq.gz 3.0 GB Report
EGAF00000825599 fastq.gz 1.5 GB Report
EGAF00000825600 fastq.gz 1.4 GB Report
EGAF00000825601 fastq.gz 2.6 GB Report
EGAF00000825602 fastq.gz 2.6 GB Report
EGAF00000825603 fastq.gz 1.4 GB Report
EGAF00000825604 fastq.gz 1.4 GB Report
EGAF00000825605 fastq.gz 2.0 GB Report
EGAF00000825606 fastq.gz 2.0 GB Report
EGAF00000825607 fastq.gz 6.5 GB Report
EGAF00000825608 fastq.gz 6.5 GB Report
EGAF00000825609 fastq.gz 2.6 GB Report
EGAF00000825610 fastq.gz 2.7 GB Report
EGAF00000825611 fastq.gz 2.6 GB Report
EGAF00000825612 fastq.gz 2.6 GB Report
EGAF00000825613 fastq.gz 2.9 GB Report
EGAF00000825614 fastq.gz 3.0 GB Report
EGAF00000825615 fastq.gz 2.8 GB Report
EGAF00000825616 fastq.gz 2.8 GB Report
EGAF00000825617 fastq.gz 2.9 GB Report
EGAF00000825618 fastq.gz 3.0 GB Report
200 Files (550.3 GB)