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Oxford Human Islet whole genome bisulphite data of 10 human pancreatic islet samples

DNA from 10 human pancreatic islet samples was processed for Whole-genome Bisulphite Sequencing. The resulting libraries were sequenced on an Illumina Hiseq 2000 to generate 100bp paired-end read data. The resulting fastq.gz and mapped bam files were deposited.

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OXFORD HUMAN ISLET DATA ACCESS AGREEMENT This agreement governs the terms on which access will be granted to the Whole genome bisulphite sequencing data generated as part of the “Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci” study. In signing this agreement, You are agreeing to be bound by the terms and conditions of access set out in this agreement. For the sake of clarity, the terms of access set out in this agreement apply both to the User and the User’s Institution (as defined below). User Institution and User are referred to within the agreement as “You” and “Your” shall be construed accordingly. Definitions: Investigators means the group of investigators based in Oxford, UK which have generated the Data. Data means all and any human genetic data obtained from the Investigators. Data Subject means a person, who has been informed of the purpose for which the Data is held and has given his/her informed consent thereto. User means a researcher whose User Institution has previously completed this Data Access Agreement and has received acknowledgement of its acceptance. Publications means, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. User Institution means the organisation at which the User is employed, affiliated or enrolled. Terms and Conditions: In signing this Agreement: 1. You agree to use the Data only for the advancement of medical research, according to the consent obtained from sample donors. 2. You agree not to use the Data or any part thereof for the creation of products for sale or for any commercial purpose. 3. You agree to preserve, at all times, the confidentiality of information and Data pertaining to Data Subjects. In particular, You undertake not to use, or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. 4. You agree not to attempt to link the data provided under this agreement to other information or archive data available for the data sets provided, even if access to that data has been formally granted to you, or it is freely available without restriction, without specific permission being sought from the relevant access committees. 5. You agree not to transfer or disclose the Data, in whole or part, or any identifiable material derived from the Data, to others, except as necessary for data/safety monitoring or programme management. Should You wish to share the Data with a collaborator outside the same Institution, the third party must make a separate application for access to the Data. 6. You agree to use the data for the approved purpose and project described in your application; use of the data for a new purpose or project will require a new application and approval. 7. You agree to acknowledge in any work based in whole or part on the Data, the published paper from which the Data derives. 8. You accept that the Investigators, the original data creators, depositors or copyright holders, or the funders of the Data or any part of the Data supplied: a. bear no legal responsibility for the accuracy or comprehensiveness of the Data; and b. accept no liability for indirect, consequential, or incidental, damages or losses arising from use of the Data, or from the unavailability of, or break in access to, the Data for whatever reason. 9. You understand and acknowledge that the Data is protected by copyright and other intellectual property rights, and that duplication, except as reasonably required to carry out Your research with the Data, or sale of all or part of the Data on any media is not permitted. 10. You recognise that nothing in this agreement shall operate to transfer to the User Institution any intellectual property rights relating to the Data. The User Institution has the right to develop intellectual property based on comparisons with their own data. 11. You accept that this agreement will terminate immediately upon any breach of this agreement by You and You will be required to destroy any Data held. 12. You accept that it may be necessary for the Investigators or its appointed agent to alter the terms of this agreement from time to time in order to address new concerns. In this event, the Investigators or its appointed agent will contact You to inform You of any changes and You agree that Your continued use of the Data shall be dependent on the parties entering into a new version of the Agreement. 13. You accept that the Data is protected by and subject to international laws, including but not limited to the UK Data Protection Act 1998, and that You are responsible for ensuring compliance with any such applicable law. The Oxford Human Islet Data Access Committee reserves the right to request and inspect data security and management documentation to ensure the adequacy of data protection measures in countries that have no national laws comparable to that which pertain in the EAA. 14. This agreement shall be construed, interpreted and governed by the laws of England and Wales and shall be subject to the non-exclusive jurisdiction of the English courts. APPENDIX: Oxford Human Islet - Data Access Application Form - ________________________________________ Application for Access to Whole genome bisulphite sequencing data Name of applicant and co-applicant(s), including affiliations and contact details. Please ensure that a full postal and email address is included for each applicant. PhD student applicants must include their supervisor(s) as co-applicant(s) and provide their full contact details. Title of Project In less than 30 words.. Research Question Please provide a clear description of the project and its specific aims in no more than 750 words. This should include specific details of what you plan to do with the data and key references. Feasibility Please describe fully your experience and expertise, and that of your collaborators, and this will be applied to the proposed study. A publication list must be provided for the applicant, co-applicant(s) and, where PhD students have applied, PhD supervisors. The Data Access Committee needs assurance of competence in handling datasets of this size and nature. I have read and agree to abide by the terms and conditions outlined in the Data Access Agreement? Signed: Name: Date:

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001002592 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00001843027 bam 40.0 GB
EGAF00001843028 bam 48.5 GB
EGAF00001843029 bam 40.0 GB
EGAF00001843030 bam 42.5 GB
EGAF00001843031 bam 41.4 GB
EGAF00001843032 bam 43.6 GB
EGAF00001843033 bam 45.6 GB
EGAF00001843034 bam 51.7 GB
EGAF00001843035 bam 54.1 GB
EGAF00001843036 bam 48.1 GB
EGAF00001843037 fastq.gz 37.7 GB
EGAF00001843038 fastq.gz 31.7 GB
EGAF00001843039 fastq.gz 33.3 GB
EGAF00001843040 fastq.gz 27.7 GB
EGAF00001843041 fastq.gz 27.5 GB
EGAF00001843042 fastq.gz 23.5 GB
EGAF00001843043 fastq.gz 34.6 GB
EGAF00001843044 fastq.gz 29.4 GB
EGAF00001843045 fastq.gz 33.1 GB
EGAF00001843046 fastq.gz 27.7 GB
EGAF00001843047 fastq.gz 35.3 GB
EGAF00001843048 fastq.gz 30.8 GB
EGAF00001843049 fastq.gz 36.2 GB
EGAF00001843050 fastq.gz 31.4 GB
EGAF00001843051 fastq.gz 39.9 GB
EGAF00001843052 fastq.gz 34.7 GB
EGAF00001843053 fastq.gz 37.4 GB
EGAF00001843054 fastq.gz 32.7 GB
EGAF00001843055 fastq.gz 38.8 GB
EGAF00001843056 fastq.gz 33.8 GB
30 Files (1.1 TB)