Dataset

The Causes of Clonal Blood Cell Disorders Study - SCOR (2018-04-19)

Dataset ID Technology Samples
EGAD00001004086 HiSeq X Ten,Illumina HiSeq 2500 207

Dataset Description

We will take a bone marrow aspirate and peripheral blood samples from a healthy patient aged around 60, and use flow cytometry to isolate 100 HSCs, 50 MEPs, and 50 GMPs. We will grow these up into colonies, then whole genome sequence each colony. Somatic mutations will act as a unique barcode for each clone. We will then design a panel for targeted resequencing of the mutations that we find. It will then be possible to look for these mutations in the peripheral blood over several years, to see the dynamics of how HSCs contribute to the peripheral blood in health.
This dataset contains all the data available for this study on 2018-04-19.

Data Use Conditions

IS PUB US

See further information on Data Use Conditions

Label Code Version Modifier
general research use DUO:0000042 2021-02-23
institution specific restriction DUO:0000028 2021-02-23
publication required DUO:0000019 2021-02-23
user specific restriction DUO:0000026 2021-02-23