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Multiple myeloma Total Therapy trial patient sequencing

DNA was obtained from either CD138+ cells from the bone marrow of multiple myeloma patients (tumor) or from stem cell harvests or peripheral blood cells from the same patient (control). 100 ng of DNA was fragmented, end-repaired, and adapters ligated using the HyperPlus kit (KAPA Biosystems). After PCR amplification the libraries were hybridized with probes against either a targeted panel consisting of 140 genes and chromosomal regions (Nimblegen) using SeqCap reagents (Nimblegen). Hybridized libraries underwent further amplification before being sequenced on a NextSeq500 (Illumina) using 75 bp paired end reads.

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UAMS - Deidentified Data Transfer Agreement 2016

Terms subject to change based on each transfer 2016 Data Transfer Agreement This Data Transfer Agreement (this "Agreement") is entered into effective as of the last signature date of this Agreement (“Effective Date”) by and between [company] ("Recipient"),and the Board of Trustees of the University of Arkansas acting for and on behalf of the University of Arkansas for Medical Sciences ("Provider") in order to document the transferof certain de-identified data, as defined below and the mutual covenants and promises hereinafter set forth as agreed to by Recipient and Provider. Provider and Recipient maybe referred to herein individually as a "Party" or collectively as the "Parties".WHEREAS, the Parties agree that this Agreement shall govern only the transfer of the Study Data, as defined herein, if the Parties agree in writing to same. 1. "Study Data" shall be defined to mean de-identified data collected under informed consent related to the research study entitled [please insert title]. 2. Provider certifies that the Study Data shall be provided in a de-identified fashion. Under no circumstances shall Provider provide Recipient with the name, address, social security number, or any other identifier which would permit Recipient to identify the research subjects from whom such Study Data was collected. The Recipient, through [recipient scientist name], certifies that they neither have nor will seek to obtain information from Provider that identifies or can be used to identify or link de-identified data to any research subject, and in the event that either receives any PHI, such PHI shall be kept confidential, not used or disclosed, and shall be immediately returned to Provider. 3. Subject to, and in accordance with terms set in this Agreement, Recipient shall use Study Data for the following research purposes only (and for no other purpose): [indicate purpose/research/reference number if applicable] 4. Recipient shall only disclose Study Data to Recipient’s employees who have a need to know and who are directly responsible for the activities related to the Purpose. The Recipient, through [recipient scientist name], who shall serve as the Principal Investigator of the research study utilizing the Study Data, will ensure that all such parties are informed of the terms and conditions under this Agreement. 5. Recipient shall not use or further disclose the Study Data other than as permitted or required by this Agreement or as otherwise required by law. Recipient shall report to Provider immediately within upon Recipient’s discovery of any unauthorized use or disclosure of the Study Data not provided for by this Agreement. Recipient shall provide the following information: (1) the nature of the use or disclosure; (2) the information used or disclosed; (3) who made the use or disclosure; and (4) what corrective action will be taken by Recipient as a result of the use or disclosure. Recipient shall take any other actions available to it to mitigate any detrimental effects of the use or disclosure. 6. Recipient and its employees shall not identify or attempt to identify the individual(s) to whom the Study Data pertains or contact or attempt to contact the individual(s) who Recipient believes to be the subject of any Study Data. The obligations set forth in this Section 6 shall survive the termination or expiration of this Agreement for any reason. 7. As principal investigator, [recipient scientist name] has agreed to provide any results gained from the analysis of the Study Data with Provider. Provider Institution shall maintain these results in confidence pending publication and/or presentation of the results of the analysis being conducted on the Study Data. However, if Recipient has not published within six (6) months of the completion of the Study at Recipient’s institution, Provider shall have the right to publish or present independently any results from its work at Provider’s institution. [this term will change to joint publication if that is what is agreed]. 8. Subject to Applicable Laws, none of Provider, Principal Investigator, or Recipient shall use the name, trademark, trade name or logo of the other in any publication, press release, or promotional material with respect to the Study without the prior written approval of the other party; provided, however, that Recipient shall have the right to identify Provider as the site at which the Study Data was generated and to identify those individuals responsible for conducting the Study. Provider retains the right to use Recipient’s name, and a non-confidential descriptor, on any and all funding applications it may seek in the future. 9. This Agreement may be terminated by either Party, for any reason, upon thirty (30) days' advance written notice to the other Party, and this Agreement may be terminated upon mutual written agreement signed by the authorized representatives of both of the Parties. Notwithstanding anything to the contrary, Recipient and [recipient scientist name] shall not use or disclose any information provided by Provider except in accordance with the terms of this Agreement and applicable law. This obligation shall extend in perpetuity. Recipient agrees that upon termination of this Agreement, Recipient shall, at its expense, (a) return or destroy all Study Data received from Provider and retain no copies of such Study Data. 10. Any notice required or permitted hereunder shall be in writing and shall be deemed given as of the date it is: (i) delivered by hand; (ii) received by registered or certified mail, postage prepaid, return receipt requested; (iii) confirmed as received if by facsimile; or (iv) received by nationally recognized, overnight courier, and addressed to the party to receive such notice at the address set forth below, or such other address as is subsequently specified in writing. If to Recipient: [ please provide ] If to Provider: University of Arkansas for Medical Sciences By Post: 4301 West Markham Drive, MS#860 Little Rock, AR 72205 By Courier: Ed II, 5th Floor, Suite 104 Little Rock, AR 72205 Attn: Sr. Research Contracts Attorney 11. Recipient and Provider shall not assign or transfer any rights or obligations hereunder, or any part hereof, without the prior written consent of the other Party. 12. Entire Agreement. This Agreement constitutes the entire agreement and understanding between the Parties and supersedes any prior or contemporaneous negotiations, agreements, understandings, or arrangements of any nature or kind with respect to the subject matter herein. 13. This Agreement may be executed simultaneously in any number of counterparts (including scanned copies of signature in portable document format “pdf” and delivered via electronic mail), each of which shall be deemed an original and all of which taken together shall constitute one and the same instrument. IN WITNESS WHEREOF, the parties have executed this Data Transfer Agreement as of the [Effective Date] Board of Trustees of the University of Arkansas [Name of Recpient] Acting For And On Behalf Of The University of Arkansas for Medical Sciences By: ___________________________________ By: ________________________ Name: Suzanne Alstadt Name: Title: Director, Office of Research and Title: Sponsored Programs Date: _________________________________ Date: ______________________ READ AND UNDERSTOOD BY PRINCIPAL INVESTIGATOR By: ________________________________ Date: _______________________________

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001003223 Other
ID File Type Size Located in
EGAF00002195140 bam 6.6 GB
EGAF00002195141 bam 4.3 GB
EGAF00002195142 bam 4.9 GB
EGAF00002195143 bam 5.5 GB
EGAF00002195144 bam 6.2 GB
EGAF00002195145 bam 5.7 GB
EGAF00002195146 bam 4.1 GB
EGAF00002195147 bam 4.3 GB
EGAF00002195148 bam 4.3 GB
EGAF00002195149 bam 6.3 GB
EGAF00002195150 bam 6.2 GB
EGAF00002195151 bam 5.2 GB
EGAF00002195152 bam 4.0 GB
EGAF00002195153 bam 3.7 GB
EGAF00002195154 bam 5.7 GB
EGAF00002195155 bam 5.9 GB
EGAF00002195156 bam 5.6 GB
EGAF00002195157 bam 3.8 GB
EGAF00002195158 bam 7.2 GB
EGAF00002195159 bam 5.3 GB
EGAF00002195160 bam 7.1 GB
EGAF00002195161 bam 5.0 GB
EGAF00002195162 bam 5.3 GB
EGAF00002195163 bam 4.2 GB
EGAF00002195164 bam 3.0 GB
EGAF00002195165 bam 6.3 GB
EGAF00002195166 bam 4.5 GB
EGAF00002195167 bam 4.2 GB
EGAF00002195168 bam 5.1 GB
EGAF00002195169 bam 4.7 GB
EGAF00002195170 bam 5.9 GB
EGAF00002195171 bam 5.1 GB
EGAF00002195172 bam 4.5 GB
EGAF00002195173 bam 4.8 GB
EGAF00002195174 bam 6.6 GB
EGAF00002195175 bam 4.8 GB
EGAF00002195176 bam 5.6 GB
EGAF00002195177 bam 3.8 GB
EGAF00002195178 bam 5.0 GB
EGAF00002195179 bam 4.5 GB
EGAF00002195180 bam 4.8 GB
EGAF00002195181 bam 5.0 GB
EGAF00002195182 bam 4.1 GB
EGAF00002195183 bam 3.7 GB
EGAF00002195184 bam 4.5 GB
EGAF00002195185 bam 3.3 GB
EGAF00002195186 bam 4.5 GB
EGAF00002195187 bam 4.1 GB
EGAF00002195188 bam 4.9 GB
EGAF00002195189 bam 4.0 GB
EGAF00002195190 bam 3.9 GB
EGAF00002195191 bam 4.7 GB
EGAF00002195192 bam 4.1 GB
EGAF00002195193 bam 3.9 GB
EGAF00002195194 bam 6.0 GB
EGAF00002195195 bam 8.0 GB
EGAF00002195196 bam 5.1 GB
EGAF00002195197 bam 4.3 GB
EGAF00002195198 bam 5.0 GB
EGAF00002195199 bam 4.2 GB
EGAF00002195200 bam 2.2 GB
EGAF00002195201 bam 2.0 GB
EGAF00002195202 bam 4.1 GB
EGAF00002195203 bam 3.7 GB
EGAF00002195204 bam 6.0 GB
EGAF00002195205 bam 3.8 GB
EGAF00002195206 bam 4.4 GB
EGAF00002195207 bam 7.2 GB
EGAF00002195208 bam 4.6 GB
EGAF00002195209 bam 3.4 GB
EGAF00002195210 bam 5.8 GB
EGAF00002195211 bam 7.2 GB
EGAF00002195212 bam 4.9 GB
EGAF00002195213 bam 6.6 GB
EGAF00002195214 bam 4.8 GB
EGAF00002195215 bam 5.2 GB
EGAF00002195216 bam 4.3 GB
EGAF00002195217 bam 3.4 GB
EGAF00002195218 bam 5.9 GB
EGAF00002195219 bam 4.8 GB
EGAF00002195220 bam 4.1 GB
EGAF00002195221 bam 4.0 GB
EGAF00002195222 bam 4.8 GB
EGAF00002195223 bam 4.3 GB
EGAF00002195224 bam 5.3 GB
EGAF00002195225 bam 5.1 GB
EGAF00002195226 bam 5.5 GB
EGAF00002195227 bam 4.9 GB
EGAF00002195228 bam 1.5 GB
EGAF00002195229 bam 5.9 GB
EGAF00002195230 bam 7.2 GB
EGAF00002195231 bam 4.0 GB
EGAF00002195232 bam 2.1 GB
EGAF00002195233 bam 6.7 GB
EGAF00002195234 bam 5.8 GB
EGAF00002195235 bam 4.8 GB
EGAF00002195236 bam 5.0 GB
EGAF00002195237 bam 3.0 GB
EGAF00002195238 bam 4.7 GB
EGAF00002195239 bam 6.5 GB
EGAF00002195240 bam 5.5 GB
EGAF00002195241 bam 6.0 GB
EGAF00002195242 bam 5.9 GB
EGAF00002195243 bam 6.5 GB
EGAF00002195244 bam 5.8 GB
EGAF00002195245 bam 6.5 GB
EGAF00002195246 bam 6.8 GB
EGAF00002195247 bam 5.9 GB
EGAF00002195248 bam 5.1 GB
EGAF00002195249 bam 4.5 GB
EGAF00002195250 bam 5.1 GB
EGAF00002195251 bam 4.3 GB
EGAF00002195252 bam 4.8 GB
EGAF00002195253 bam 4.8 GB
EGAF00002195254 bam 5.6 GB
EGAF00002195255 bam 4.5 GB
EGAF00002195256 bam 5.4 GB
EGAF00002195257 bam 4.6 GB
EGAF00002195258 bam 5.1 GB
EGAF00002195259 bam 4.2 GB
EGAF00002195260 bam 4.2 GB
EGAF00002195261 bam 3.9 GB
EGAF00002195262 bam 4.5 GB
EGAF00002195263 bam 6.3 GB
EGAF00002195264 bam 3.9 GB
EGAF00002195265 bam 3.7 GB
EGAF00002195266 bam 2.3 GB
EGAF00002195267 bam 1.8 GB
EGAF00002195268 bam 4.5 GB
EGAF00002195269 bam 4.0 GB
EGAF00002195270 bam 4.5 GB
EGAF00002195271 bam 7.0 GB
EGAF00002195272 bam 2.4 GB
EGAF00002195273 bam 2.0 GB
EGAF00002195274 bam 4.8 GB
EGAF00002195275 bam 4.1 GB
EGAF00002195276 bam 2.3 GB
EGAF00002195277 bam 953.0 MB
EGAF00002195278 bam 1.4 GB
EGAF00002195279 bam 1.7 GB
EGAF00002195280 bam 2.3 GB
EGAF00002195281 bam 1.7 GB
EGAF00002195282 bam 1.7 GB
EGAF00002195283 bam 1.8 GB
EGAF00002195284 bam 3.5 GB
EGAF00002195285 bam 5.8 GB
EGAF00002195286 bam 2.2 GB
EGAF00002195287 bam 1.8 GB
EGAF00002195288 bam 2.5 GB
EGAF00002195289 bam 1.9 GB
EGAF00002195290 bam 4.6 GB
EGAF00002195291 bam 4.8 GB
EGAF00002195292 bam 2.1 GB
EGAF00002195293 bam 2.8 GB
EGAF00002195294 bam 2.4 GB
EGAF00002195295 bam 1.8 GB
EGAF00002195296 bam 1.4 GB
EGAF00002195297 bam 4.5 GB
EGAF00002195298 bam 5.7 GB
EGAF00002195299 bam 4.7 GB
EGAF00002195300 bam 4.1 GB
EGAF00002195301 bam 3.7 GB
EGAF00002195302 bam 6.3 GB
EGAF00002195303 bam 4.5 GB
EGAF00002195304 bam 4.3 GB
EGAF00002195305 bam 4.3 GB
EGAF00002195306 bam 5.9 GB
EGAF00002195307 bam 4.6 GB
EGAF00002195308 bam 5.5 GB
EGAF00002195309 bam 3.8 GB
EGAF00002195310 bam 6.1 GB
EGAF00002195311 bam 5.1 GB
EGAF00002195312 bam 5.7 GB
EGAF00002195313 bam 4.4 GB
EGAF00002195314 bam 5.6 GB
EGAF00002195315 bam 2.9 GB
EGAF00002195316 bam 6.4 GB
EGAF00002195317 bam 4.3 GB
EGAF00002195318 bam 4.4 GB
EGAF00002195319 bam 4.4 GB
EGAF00002195320 bam 6.0 GB
EGAF00002195321 bam 5.3 GB
EGAF00002195322 bam 6.1 GB
EGAF00002195323 bam 3.9 GB
EGAF00002195324 bam 5.1 GB
EGAF00002195325 bam 6.4 GB
EGAF00002195326 bam 7.1 GB
EGAF00002195327 bam 5.8 GB
EGAF00002195328 bam 4.2 GB
EGAF00002195329 bam 5.9 GB
EGAF00002195330 bam 3.1 GB
EGAF00002195331 bam 6.2 GB
EGAF00002195332 bam 4.3 GB
EGAF00002195333 bam 1.8 GB
EGAF00002195334 bam 1.7 GB
EGAF00002195335 bam 6.2 GB
EGAF00002195336 bam 4.8 GB
EGAF00002195337 bam 1.6 GB
EGAF00002195338 bam 1.6 GB
EGAF00002195339 bam 6.8 GB
EGAF00002195340 bam 5.7 GB
EGAF00002195341 bam 4.7 GB
EGAF00002195342 bam 4.0 GB
EGAF00002195343 bam 2.3 GB
EGAF00002195344 bam 2.0 GB
EGAF00002195345 bam 4.7 GB
EGAF00002195346 bam 4.7 GB
EGAF00002195347 bam 5.6 GB
EGAF00002195348 bam 6.6 GB
EGAF00002195349 bam 2.8 GB
EGAF00002195350 bam 6.7 GB
EGAF00002195351 bam 2.5 GB
EGAF00002195352 bam 6.3 GB
EGAF00002195353 bam 5.0 GB
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EGAF00002195355 bam 3.9 GB
EGAF00002195356 bam 8.6 GB
EGAF00002195357 bam 1.5 GB
EGAF00002195358 bam 1.6 GB
EGAF00002195359 bam 5.6 GB
EGAF00002195360 bam 4.6 GB
EGAF00002195361 bam 5.1 GB
EGAF00002195362 bam 4.0 GB
EGAF00002195363 bam 4.6 GB
EGAF00002195364 bam 4.8 GB
EGAF00002195365 bam 5.2 GB
EGAF00002195366 bam 4.5 GB
EGAF00002195367 bam 6.5 GB
EGAF00002195368 bam 5.8 GB
EGAF00002195369 bam 4.9 GB
EGAF00002195370 bam 5.0 GB
EGAF00002195371 bam 5.8 GB
EGAF00002195372 bam 5.9 GB
EGAF00002195373 bam 3.1 GB
EGAF00002195374 bam 4.2 GB
EGAF00002195375 bam 2.9 GB
EGAF00002195376 bam 6.9 GB
EGAF00002195377 bam 3.0 GB
EGAF00002195378 bam 4.2 GB
EGAF00002195379 bam 10.7 GB
EGAF00002195380 bam 5.9 GB
EGAF00002195381 bam 3.1 GB
EGAF00002195382 bam 4.4 GB
EGAF00002195383 bam 3.0 GB
EGAF00002195384 bam 1.8 GB
EGAF00002195385 bam 3.5 GB
EGAF00002195386 bam 4.2 GB
EGAF00002195387 bam 4.6 GB
EGAF00002195388 bam 6.9 GB
EGAF00002195389 bam 4.9 GB
EGAF00002195390 bam 6.4 GB
EGAF00002195391 bam 3.8 GB
EGAF00002195392 bam 8.5 GB
EGAF00002195393 bam 5.1 GB
EGAF00002195394 bam 8.2 GB
EGAF00002195395 bam 4.8 GB
EGAF00002195396 bam 8.1 GB
EGAF00002195397 bam 5.5 GB
EGAF00002195398 bam 8.8 GB
EGAF00002195399 bam 5.5 GB
EGAF00002195400 bam 8.4 GB
EGAF00002195401 bam 5.9 GB
EGAF00002195402 bam 5.3 GB
263 Files (1.2 TB)