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Extreme intratumor heterogeneity and driver evolution in mismatch repair deficient gastro-esophageal cancer

The dataset includes multi-region exome sequencing (MSeq) of four resected treatment naïve mismatch repair deficient gastro-esophageal cancers. Paired-end sequencing was performed on the Illumina HiSeq 2500 or NovaSeq 6000 with a target depth of 200X. Seven primary tumor regions along with tumor-adjacent non malignant tissue were subjected to MSeq. An additional two lymph node metastases were also included from each of two cases.

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Access to data will be granted to qualified researchers for academic/non-commercial research use subject to signing a data transfer agreement which restricts publication and dissemination of the the dataset and which prohibits any attempt to re-identify any of the study patients. If you need to request access to this data set, please contact: Translational Oncogenomics Lab - Data Access Committee marco.gerlinger@icr.ac.uk

Access to data will be granted to qualified researchers for academic/non-commercial research use subject to signing a data transfer agreement which restricts publication and dissemination of the the dataset and which prohibits any attempt to re-identify any of the study patients. If you need to request access to this data set, please contact: Translational Oncogenomics Lab - Data Access Committee marco.gerlinger@icr.ac.uk

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001003434 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002337983 bam 9.3 GB
EGAF00002337984 bam 4.9 GB
EGAF00002337985 bam 9.4 GB
EGAF00002337986 bam 10.5 GB
EGAF00002337987 bam 10.1 GB
EGAF00002337988 bam 10.8 GB
EGAF00002337989 bam 9.8 GB
EGAF00002337990 bam 9.4 GB
EGAF00002337991 bam 10.8 GB
EGAF00002337992 bam 10.2 GB
EGAF00002337993 bam 9.8 GB
EGAF00002337994 bam 4.4 GB
EGAF00002337995 bam 9.5 GB
EGAF00002337996 bam 10.4 GB
EGAF00002337997 bam 9.6 GB
EGAF00002337998 bam 9.3 GB
EGAF00002337999 bam 11.3 GB
EGAF00002338000 bam 9.2 GB
EGAF00002338001 bam 9.8 GB
EGAF00002338002 bam 9.5 GB
EGAF00002338003 bam 18.5 GB
EGAF00002338004 bam 18.2 GB
EGAF00002338005 bam 19.9 GB
EGAF00002338006 bam 19.4 GB
EGAF00002338008 bam 16.3 GB
EGAF00002338009 bam 17.3 GB
EGAF00002338010 bam 18.7 GB
EGAF00002338011 bam 9.1 GB
EGAF00002338012 bam 18.7 GB
EGAF00002338013 bam 19.2 GB
EGAF00002338014 bam 16.5 GB
EGAF00002338015 bam 16.2 GB
EGAF00002338016 bam 17.2 GB
EGAF00002338017 bam 17.9 GB
EGAF00002338018 bam 18.7 GB
35 Files (449.6 GB)