Genomic Signatures Reveal DNA Damage Response Deficiency in Brain Metastases of Colorectal Cancer

Dataset ID Technology Samples
EGAD00001005030 N/A 38

Dataset Description

Brain metastasis (BM) of colorectal cancer (CRC) is rare but lethal and lacks effective therapies or a good understanding of its genomic landscapes. We conduct an analysis of whole-exome sequencing (WES, Illumina HiSeq 2500 sequencing platform) on 11 patient-matched BMs, primary CRC tumours, and adjacent normal tissues; and whole-genome sequencing (WGS, Illumina HiSeq X Ten platform) on 8 patient-matched BMs, primary CRC tumors, and adjacent normal tissues to uncover the whole-genome mutational landscape of colorectal cancer with brain metastasis.

Who controls access to this dataset

For each dataset that requires controlled access, there is a corresponding Data Access Committee (DAC) who determine access permissions. Access to actual data files is not managed by the EGA. If you need to request access to this data set, please contact:

Data Access Commitee of The First Affiliated Hospital of Nanjing Medical University
Contact person: Jing Sun
Email: sunj [at] njmu [dot] edu [dot] cn
More details: EGAC00001001209


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