Dataset

Single-cell TCR sequencing of DQ2.5-hor-3-specific T cells

Dataset ID Technology Samples
EGAD00001005048 Illumina MiSeq 14

Dataset Description

In order to characterize the T cell receptor (TCR) repertoire of DQ2.5-hor-3-specific T cells, we performed high-throughput DNA sequencing of rearranged TCR-α and TCR-β genes of the single HLA-DQ2.5:DQ2.5-hor-3- tetramer binding CD4+ T cells isolated from biopsies of celiac disease patients. We also sequenced the TCR of the T-cell clones (TCCs) that were generated by cloning by limited dilution and antigen-free expansion of HLA-DQ2.5:DQ2.5-hor-3-tetramer binding CD4+ T cells from biopsies of celiac disease patients.

Who controls access to this dataset

For each dataset that requires controlled access, there is a corresponding Data Access Committee (DAC) who determine access permissions. Access to actual data files is not managed by the EGA. If you need to request access to this data set, please contact:

Single cell TCR sequencing data access commitee
Contact person: Ludvig M. Sollid
Email: l [dot] m [dot] sollid [at] medisin [dot] uio [dot] no
More details: EGAC00001001218

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