Analysis of resistance to PLX4032 (2019-08-21)
We have collected material from a patient who had BrafV600E mutant melanoma that was treated with PLX4032. We have germline DNA from the patient and DNA and RNA from distinct lesions before and after treatment with PLX4032. We would like to exome sequence these samples to gain a snap shot of the mechanisms of resistance that are operative. . This dataset contains all the data available for this study on 2019-08-21.
- 21/08/2019
- 42 samples
- DAC: EGAC00001000205
- Technology: Illumina HiSeq 2000
Wellcome Trust Sanger Institute Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001000415 | Other |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
i
|
|---|---|---|---|---|
| EGAF00000238561 | bam | 3.9 GB | Report |
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| EGAF00000238562 | bam | 6.1 GB | Report |
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| EGAF00000238563 | bam | 4.7 GB | Report |
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| EGAF00000238564 | bam | 3.7 GB | Report |
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| EGAF00000238565 | bam | 4.3 GB | Report |
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| EGAF00000238566 | bam | 3.2 GB | Report |
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| EGAF00000238567 | bam | 4.4 GB | Report |
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| EGAF00000239224 | bam | 4.7 GB | Report |
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| EGAF00000239225 | bam | 7.4 GB | Report |
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| EGAF00000239226 | bam | 5.6 GB | Report |
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| EGAF00000239227 | bam | 4.5 GB | Report |
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| EGAF00000239228 | bam | 5.2 GB | Report |
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| EGAF00000239229 | bam | 3.9 GB | Report |
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| EGAF00000239230 | bam | 5.3 GB | Report |
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| EGAF00000510390 | cram | 5.1 GB | Report |
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| EGAF00000510391 | cram | 5.1 GB | Report |
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| EGAF00000510392 | cram | 6.6 GB | Report |
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| EGAF00000510393 | cram | 2.5 GB | Report |
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| EGAF00000510394 | cram | 1.7 GB | Report |
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| EGAF00000510395 | cram | 1.7 GB | Report |
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| EGAF00000510396 | cram | 2.4 GB | Report |
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| EGAF00000510397 | cram | 1.9 GB | Report |
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| EGAF00000510398 | cram | 2.0 GB | Report |
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| EGAF00000510399 | cram | 2.9 GB | Report |
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| EGAF00000512185 | cram | 3.0 GB | Report |
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| EGAF00000512186 | cram | 2.1 GB | Report |
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| EGAF00000512187 | cram | 2.0 GB | Report |
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| EGAF00000512188 | cram | 2.9 GB | Report |
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| EGAF00000512189 | cram | 2.2 GB | Report |
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| EGAF00000512190 | cram | 2.4 GB | Report |
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| EGAF00000512191 | cram | 3.5 GB | Report |
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| EGAF00000563063 | cram | 3.2 GB | Report |
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| EGAF00000563064 | cram | 4.5 GB | Report |
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| EGAF00000563065 | cram | 3.5 GB | Report |
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| EGAF00000563066 | cram | 2.0 GB | Report |
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| EGAF00000563067 | cram | 4.9 GB | Report |
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| EGAF00000563068 | cram | 4.0 GB | Report |
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| EGAF00000563069 | cram | 2.2 GB | Report |
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| EGAF00000563070 | cram | 3.1 GB | Report |
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| EGAF00000563071 | cram | 4.2 GB | Report |
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| EGAF00000563072 | cram | 2.4 GB | Report |
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| EGAF00000563073 | cram | 3.4 GB | Report |
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| EGAF00000563074 | cram | 2.8 GB | Report |
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| EGAF00000563075 | cram | 3.9 GB | Report |
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| EGAF00000563076 | cram | 3.1 GB | Report |
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| EGAF00000563077 | cram | 1.8 GB | Report |
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| EGAF00000563078 | cram | 4.3 GB | Report |
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| EGAF00000563079 | cram | 3.5 GB | Report |
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| EGAF00000563080 | cram | 2.9 GB | Report |
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| EGAF00000563081 | cram | 4.0 GB | Report |
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| EGAF00000563082 | cram | 5.4 GB | Report |
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| EGAF00000563083 | cram | 3.1 GB | Report |
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| EGAF00000563084 | cram | 4.4 GB | Report |
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| EGAF00001385707 | cram | 1.6 GB | Report |
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| EGAF00001385708 | cram | 1.6 GB | Report |
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| EGAF00001385709 | cram | 1.8 GB | Report |
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| EGAF00001385710 | cram | 1.8 GB | Report |
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| EGAF00001385711 | cram | 2.9 GB | Report |
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| EGAF00001385712 | cram | 2.3 GB | Report |
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| EGAF00001385713 | cram | 1.7 GB | Report |
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| EGAF00001385714 | cram | 2.1 GB | Report |
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| EGAF00001385715 | cram | 2.3 GB | Report |
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| EGAF00001385716 | cram | 1.5 GB | Report |
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| EGAF00001385717 | cram | 3.0 GB | Report |
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| EGAF00001385718 | cram | 1.9 GB | Report |
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| EGAF00001385719 | cram | 2.3 GB | Report |
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| EGAF00001385720 | cram | 2.4 GB | Report |
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| 67 Files (222.4 GB) | ||||