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A compendium of mutational signatures due to environmental exposures

Analysis of mutational signatures caused by exposure to known mutagens in human induced pluripotent stem (iPS) cells. A reference human iPS cell-line will be exposed to 100 chemicals known or proposed to be mutagenic. Following exposure to mutagen, cells will undergo a period of recovery before sub clones are generated and sequenced. The progenitor "parental" IPS cell-line will be used to generate reference sequence data, in order to determine the mutational signatures acquired as a result of exposure to different mutagens.

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Wellcome Trust Sanger Institute Data Sharing Policy

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001002060 Whole Genome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002374179 cram 45.1 GB
EGAF00002374180 cram 35.5 GB
EGAF00002374181 cram 33.8 GB
EGAF00002374182 cram 5.3 GB
EGAF00002384070 cram 141.0 MB
EGAF00002384071 cram 125.9 MB
EGAF00002384072 cram 118.5 MB
EGAF00002384073 cram 112.6 MB
EGAF00002384074 cram 156.6 MB
EGAF00002384075 cram 157.5 MB
EGAF00002384076 cram 11.2 GB
11 Files (131.7 GB)