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Circulating tumor DNA in urine and plasma of glioma patients - sequencing data

Dataset consisting of sequence data from 36 glioma patients. Data includes; -Whole exome sequencing of tumour tissue and matched germline -Shallow whole genome sequencing of urine cell-free DNA -Targeted capture sequencing of plasma and CSF cell-free DNA Additional sequencing data are provided from non-glioma and healthy controls

Request Access

Policy for access to data included in the following publication; Cell-free DNA fragmentation patterns and personalized sequencing reveal circulating tumor DNA in urine and plasma of glioma patients. Its terms and conditions govern access to and use of the managed access datasets to which the User Institution has requested access. The User Institution and User agree to be bound by these terms and conditions.

Definitions: Confidential Information: means any information provided by the Data Provider relating to the Data Data: The managed access dataset(s) to which the User Institution has requested access, as detailed in Schedule B. Data Provider: THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE of The Old Schools, Trinity Lane, Cambridge CB2 1TN, United Kingdom and the Cambridge University Hospitals NHS Foundation Trust of Addenbrooke’s Hospital, Cambridge, CB2 0QQ; represented by staff of the Rosenfeld Group at the Cancer Research UK Cambridge Institute, and contactable by email at Rosenfeld.LabAdmin@cruk.cam.ac.uk or future email as updated; or future representatives as indicated in Data Access Committee(s) for the dataset(s) defined in Schedule B. Data Subject: means an individual who participated in research studies from whom the Data was derived. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Personal Data: means information and/or data about one or more living person who is the subject of personal data and who can be identified from that information, as provided under the General Data Protection Regulation (EU) 2016/679 (as amended from time to time), including but not limited to surname, initials, date of birth, address and postcodes, national insurance number, hospital number or NHS number. Project: The research project for which the User Institution has requested access to these Data, as defined in Schedule B. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. User Institution is referred to within this Agreement as “You” (and “Your” shall be construed accordingly). Data Provider will provide access to Data to the User Institution under the following Terms and Conditions: 1. You agree to preserve, at all times, the confidentiality and privacy of information and Data pertaining to Data Subjects. In particular, you undertake not to use, or attempt to use the Data to compromise or otherwise breach or infringe the confidentiality and privacy of information on Data Subjects. You agree to protect the confidentiality of Data Subjects in any Publications that you prepare by taking all reasonable care to limit the possibility of identification. You agree not to attempt to link Data to any other data source on the same samples, link the Data to any person or otherwise identify any Data Subject from the Data. 2. You agree not to transfer or disclose the Data, in whole or part, to others, except to persons within the User Institution for carrying out the Project or as reasonably necessary for Data/safety monitoring or programme management. If You wish to disclose the Data to a collaborator outside the User Institution, the third party must make a separate application for access to the Data. 3. You agree to use the Data for the advancement of medical research, and solely for the approved purpose and Project described in Schedule B and for no other purpose. 4. You agree that Data may be reissued from time to time, with suitable versioning. If the reissue is at the request of Data Subjects and/or other ethical scrutiny or concerns, you will destroy earlier versions of the Data, and upon request of Data Provider, provide written certification of such destruction. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 5. You agree to acknowledge in any Publication based in whole or part on the Data, the published paper(s) from which the Data derives, and the version of the Data. 6. You agree and acknowledge that the researchers of this study, the original Data creators, depositors, or copyright holders, and the Data Provider: a) bear no legal responsibility or liability for the accuracy or comprehensiveness of the Data, or from any use of the Data including further analysis or interpretation of such Data; and b) shall have no liability for any direct or indirect, consequential, or incidental damages or losses whatsoever arising out of Your use of the Data, or from the unavailability of, or lack of access to, the Data for whatever reason; and c) disclaim any and all representations, conditions or warranties (either express, implied or statutory) regarding the Data, including accuracy of the Data or that the Data corresponds with a particular description or is fit for a particular purpose. 7. You understand and acknowledge that the Data is owned by Data Provider and its collaborators and is protected by copyright, database rights and other intellectual property rights. You agree that you shall not reproduce or copy the Data, except as reasonably required to carry out the Project and for no other purpose, or sell all or any part of the Data in any circumstances. 8. You recognise that by granting You access to Data, no rights or ownership or intellectual property rights in or relating to the Data are transferred to You. 9. Upon any breach by You of the terms set out in this form, You will be required to destroy the Data in Your possession, and upon request, provide written certification to the Data Provider of such destruction. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 10. You accept that it may be necessary for the Data Provider to alter the terms of use of the Data from time to time. As an example, this may include specific provisions relating to the Data required by Data Provider or collaborator parties. In the event that changes are required, the Data Provider or their appointed agent will contact You to inform You of the changes and You may elect either to accept the changes or to destroy the Data in Your possession and cease its use. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 11. You agree that the Data is protected by and subject to applicable international laws. You are responsible for ensuring compliance with any such laws. The Data Provider reserves the right to request and inspect Your data security and management documentation to ensure the adequacy and compliance of data protection measures pertaining to storage and use of Data. 12. If the Data includes any identifiable Personal Data, You agree to: (a) take appropriate technical and organisational measures against the unauthorised or unlawful processing and/or use of the Data, any data derived from the Data and/or and all Confidential Information, against the accidental loss or destruction of, or damage to, such data and information. (b) ensure that the measures referred to in (a) shall include the measures set out in Schedule A. (c) restrict access to the Data, any data derived from the Data and all other Confidential Information to employees who strictly need access to such data and/or information to undertake the Project, and shall ensure that all such employees are reliable, and informed of the confidential nature of such data and/or information and the importance of processing it securely. (d) For the avoidance of doubt, You undertake not to disclose to a third party, whether in connection with the Project or otherwise, any data and/or information contained in or derived from the Data which constitutes Personal Data. Schedule A 1.1 You acknowledge and agree that the Data is pseudonymised Data and that You will become the Data Controller on receipt of such Data. 1.2 You will only process the Data for the purpose of carrying out the Project. 1.3 You agree that safeguards required under Article 89(1) of GDPR, and relevant conditions under the Data Protection Act 2018, are satisfied, and in particular that: (i) the processing of Data under or in connection with this Agreement is in the public interest; and (ii) if applicable, the Project has been subject to ethical review by an appropriate institutional review board or independent ethics committee. 1.4 The Data Provider does not intend to provide any information that may lead to You being able to identify any individual from whom any Data has been obtained. 1.5 You agree that You shall not analyse or make any use of any Data where it is reasonably foreseeable that such analysis or use may lead to the identification of any Data Subject or compromise the anonymity of any Data Subject in any way. 1.6 You shall notify the Data Provider immediately of any actual or suspected breach of security which involves the Data. Schedule B Name of the applicant and co-applicant(s), including affiliations, titles and contact details. For dataset deposited at EGA, applicants must have registered accounts at EGA. Student applicants must include their supervisors as a co-applicant. Name of registered user; Email; Job title; Supervisor*; Title of Project (in less than 30 words) Data Requested (please indicate relevant publication(s) describing the data, accession number(s) and/or relevant links to data, and [where relevant] details of and links to the respective Data Access Committee(s) (DAC)) Research Project: Please provide a clear description of the project and its specific aims in no more than 750 words. This should include specific details of what you plan to do with the data and include key references. Brief description of the infrastructure and experience for handling the requested data securely Signature of authorized signatory of User Institution Signature; Name; Title; Date; Signature of Principal Investigator I confirm that I have read and understood the TERMS AND CONDITIONS as set forth in this DATA ACCESS REQUEST FORM. Signature; Name; Title; Date; ~~~~~~~ Data Access Request Form, V1 CRUK-CI, Rosenfeld Lab, July 2019

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001004355 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00003941627 fq.gz 315.9 MB
EGAF00003941628 fq.gz 347.6 MB
EGAF00003941629 fq.gz 314.5 MB
EGAF00003941630 fq.gz 348.8 MB
EGAF00003941631 fq.gz 291.3 MB
EGAF00003941632 fq.gz 313.0 MB
EGAF00003941633 fq.gz 294.1 MB
EGAF00003941634 fq.gz 317.3 MB
EGAF00003941635 fq.gz 293.7 MB
EGAF00003941636 fq.gz 318.5 MB
EGAF00003941637 fq.gz 292.4 MB
EGAF00003941638 fq.gz 319.3 MB
EGAF00003941639 fq.gz 294.9 MB
EGAF00003941640 fq.gz 319.7 MB
EGAF00003941641 fq.gz 298.9 MB
EGAF00003941642 fq.gz 325.3 MB
EGAF00003941643 fq.gz 297.8 MB
EGAF00003941644 fq.gz 325.5 MB
EGAF00003941645 fq.gz 296.3 MB
EGAF00003941646 fq.gz 326.4 MB
EGAF00003941647 fq.gz 333.4 MB
EGAF00003941648 fq.gz 362.9 MB
EGAF00003941649 fq.gz 336.4 MB
EGAF00003941650 fq.gz 367.2 MB
EGAF00003941651 fq.gz 335.0 MB
EGAF00003941652 fq.gz 367.7 MB
EGAF00003941653 fq.gz 333.8 MB
EGAF00003941654 fq.gz 369.1 MB
EGAF00003941655 fq.gz 287.7 MB
EGAF00003941656 fq.gz 312.4 MB
EGAF00003941657 fq.gz 291.5 MB
EGAF00003941658 fq.gz 317.7 MB
EGAF00003941659 fq.gz 289.7 MB
EGAF00003941660 fq.gz 317.5 MB
EGAF00003941661 fq.gz 287.1 MB
EGAF00003941662 fq.gz 316.6 MB
EGAF00003941663 fq.gz 246.9 MB
EGAF00003941664 fq.gz 263.4 MB
EGAF00003941665 fq.gz 249.2 MB
EGAF00003941666 fq.gz 267.2 MB
EGAF00003941667 fq.gz 248.5 MB
EGAF00003941668 fq.gz 267.9 MB
EGAF00003941669 fq.gz 246.8 MB
EGAF00003941670 fq.gz 267.5 MB
EGAF00003941671 fq.gz 306.0 MB
EGAF00003941672 fq.gz 331.9 MB
EGAF00003941673 fq.gz 309.8 MB
EGAF00003941674 fq.gz 337.1 MB
EGAF00003941675 fq.gz 307.8 MB
EGAF00003941676 fq.gz 336.6 MB
EGAF00003941677 fq.gz 306.7 MB
EGAF00003941678 fq.gz 337.8 MB
EGAF00003941679 fq.gz 555.7 MB
EGAF00003941680 fq.gz 616.0 MB
EGAF00003941681 fq.gz 612.0 MB
EGAF00003941682 fq.gz 680.1 MB
EGAF00003941683 fq.gz 621.8 MB
EGAF00003941684 fq.gz 676.2 MB
EGAF00003941685 fq.gz 562.0 MB
EGAF00003941686 fq.gz 623.2 MB
EGAF00003941687 fq.gz 619.4 MB
EGAF00003941688 fq.gz 686.5 MB
EGAF00003941689 fq.gz 597.9 MB
EGAF00003941690 fq.gz 661.0 MB
EGAF00003941691 fq.gz 560.6 MB
EGAF00003941692 fq.gz 622.0 MB
EGAF00003941693 fq.gz 598.9 MB
EGAF00003941694 fq.gz 661.5 MB
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EGAF00003941696 fq.gz 708.2 MB
EGAF00003941697 fq.gz 535.7 MB
EGAF00003941698 fq.gz 576.0 MB
EGAF00003941699 fq.gz 565.7 MB
EGAF00003941700 fq.gz 620.7 MB
EGAF00003941701 fq.gz 536.8 MB
EGAF00003941702 fq.gz 586.2 MB
EGAF00003941703 fq.gz 572.7 MB
EGAF00003941704 fq.gz 623.8 MB
EGAF00003941705 fq.gz 620.0 MB
EGAF00003941706 fq.gz 696.4 MB
EGAF00003941707 fq.gz 549.9 MB
EGAF00003941708 fq.gz 609.9 MB
EGAF00003941709 fq.gz 520.2 MB
EGAF00003941710 fq.gz 563.5 MB
EGAF00003941711 fq.gz 579.9 MB
EGAF00003941712 fq.gz 647.2 MB
EGAF00003941713 fq.gz 618.3 MB
EGAF00003941714 fq.gz 689.6 MB
EGAF00003941715 fq.gz 576.2 MB
EGAF00003941716 fq.gz 641.1 MB
EGAF00003941717 fq.gz 305.4 MB
EGAF00003941718 fq.gz 328.4 MB
EGAF00003941719 fq.gz 507.5 MB
EGAF00003941720 fq.gz 554.2 MB
EGAF00003941721 fq.gz 233.2 MB
EGAF00003941722 fq.gz 250.7 MB
EGAF00003941723 fq.gz 604.9 MB
EGAF00003941724 fq.gz 663.1 MB
EGAF00003941725 fq.gz 302.9 MB
EGAF00003941726 fq.gz 324.4 MB
EGAF00003941727 fq.gz 569.8 MB
EGAF00003941728 fq.gz 612.7 MB
EGAF00003941729 fq.gz 309.5 MB
EGAF00003941730 fq.gz 331.1 MB
EGAF00003941731 fq.gz 660.2 MB
EGAF00003941732 fq.gz 725.3 MB
EGAF00003941733 fq.gz 340.6 MB
EGAF00003941734 fq.gz 367.5 MB
EGAF00003941735 fq.gz 563.8 MB
EGAF00003941736 fq.gz 618.2 MB
EGAF00003941737 fq.gz 261.2 MB
EGAF00003941738 fq.gz 281.7 MB
EGAF00003941739 fq.gz 483.8 MB
EGAF00003941740 fq.gz 525.4 MB
EGAF00003941741 fq.gz 338.1 MB
EGAF00003941742 fq.gz 363.2 MB
EGAF00003941743 fq.gz 670.7 MB
EGAF00003941744 fq.gz 744.5 MB
EGAF00003941745 fq.gz 346.3 MB
EGAF00003941746 fq.gz 371.6 MB
EGAF00003941747 fq.gz 570.4 MB
EGAF00003941748 fq.gz 624.9 MB
EGAF00003941749 fq.gz 327.3 MB
EGAF00003941750 fq.gz 346.7 MB
EGAF00003941751 fq.gz 376.9 MB
EGAF00003941752 fq.gz 402.9 MB
EGAF00003941753 fq.gz 250.4 MB
EGAF00003941754 fq.gz 264.8 MB
EGAF00003941755 fq.gz 659.5 MB
EGAF00003941756 fq.gz 730.3 MB
EGAF00003941757 fq.gz 324.7 MB
EGAF00003941758 fq.gz 341.7 MB
EGAF00003941759 fq.gz 660.9 MB
EGAF00003941760 fq.gz 730.7 MB
EGAF00003941761 fq.gz 330.7 MB
EGAF00003941762 fq.gz 347.6 MB
EGAF00003941763 fq.gz 588.5 MB
EGAF00003941764 fq.gz 661.1 MB
EGAF00003941765 fq.gz 306.9 MB
EGAF00003941766 fq.gz 331.0 MB
EGAF00003941767 fq.gz 598.2 MB
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EGAF00003941769 fq.gz 235.5 MB
EGAF00003941770 fq.gz 253.9 MB
EGAF00003941771 fq.gz 534.7 MB
EGAF00003941772 fq.gz 584.1 MB
EGAF00003941773 fq.gz 304.7 MB
EGAF00003941774 fq.gz 327.0 MB
EGAF00003941775 fq.gz 474.7 MB
EGAF00003941776 fq.gz 530.7 MB
EGAF00003941777 fq.gz 310.6 MB
EGAF00003941778 fq.gz 333.2 MB
EGAF00003941779 fq.gz 618.1 MB
EGAF00003941780 fq.gz 692.0 MB
EGAF00003941781 fq.gz 342.9 MB
EGAF00003941782 fq.gz 368.4 MB
EGAF00003941783 fq.gz 639.1 MB
EGAF00003941784 fq.gz 709.6 MB
EGAF00003941785 fq.gz 262.3 MB
EGAF00003941786 fq.gz 281.7 MB
EGAF00003941787 fq.gz 672.4 MB
EGAF00003941788 fq.gz 743.5 MB
EGAF00003941789 fq.gz 339.8 MB
EGAF00003941790 fq.gz 363.3 MB
EGAF00003941791 fq.gz 559.3 MB
EGAF00003941792 fq.gz 599.2 MB
EGAF00003941793 fq.gz 346.8 MB
EGAF00003941794 fq.gz 370.0 MB
EGAF00003941795 fq.gz 660.7 MB
EGAF00003941796 fq.gz 730.5 MB
EGAF00003941797 fq.gz 322.6 MB
EGAF00003941798 fq.gz 347.5 MB
EGAF00003941799 fq.gz 629.6 MB
EGAF00003941800 fq.gz 688.9 MB
EGAF00003941801 fq.gz 246.1 MB
EGAF00003941802 fq.gz 265.0 MB
EGAF00003941803 fq.gz 555.4 MB
EGAF00003941804 fq.gz 614.2 MB
EGAF00003941805 fq.gz 318.5 MB
EGAF00003941806 fq.gz 341.4 MB
EGAF00003941807 fq.gz 649.9 MB
EGAF00003941808 fq.gz 724.5 MB
EGAF00003941809 fq.gz 325.4 MB
EGAF00003941810 fq.gz 348.5 MB
EGAF00003941811 fq.gz 513.2 MB
EGAF00003941812 fq.gz 555.5 MB
EGAF00003941813 fq.gz 304.9 MB
EGAF00003941814 fq.gz 328.7 MB
EGAF00003941815 fq.gz 233.0 MB
EGAF00003941816 fq.gz 251.2 MB
EGAF00003941817 fq.gz 543.0 MB
EGAF00003941818 fq.gz 601.1 MB
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EGAF00003941820 fq.gz 324.6 MB
EGAF00003941821 fq.gz 611.3 MB
EGAF00003941822 fq.gz 681.3 MB
EGAF00003941823 fq.gz 310.0 MB
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EGAF00003941825 fq.gz 656.4 MB
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EGAF00003941828 fq.gz 356.1 MB
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EGAF00003941832 fq.gz 273.3 MB
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EGAF00003941836 fq.gz 352.6 MB
EGAF00003941837 fq.gz 334.6 MB
EGAF00003941838 fq.gz 358.4 MB
EGAF00003941839 fq.gz 353.4 MB
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EGAF00003941842 fq.gz 821.6 MB
EGAF00003941843 fq.gz 271.2 MB
EGAF00003941844 fq.gz 291.1 MB
EGAF00003941845 fq.gz 648.1 MB
EGAF00003941846 fq.gz 735.4 MB
EGAF00003941847 fq.gz 350.8 MB
EGAF00003941848 fq.gz 375.3 MB
EGAF00003941849 fq.gz 436.1 MB
EGAF00003941850 fq.gz 475.2 MB
EGAF00003941851 fq.gz 357.5 MB
EGAF00003941852 fq.gz 381.7 MB
EGAF00003941853 fq.gz 646.0 MB
EGAF00003941854 fq.gz 744.5 MB
EGAF00003941855 fq.gz 295.6 MB
EGAF00003941856 fq.gz 312.2 MB
EGAF00003941857 fq.gz 510.6 MB
EGAF00003941858 fq.gz 574.8 MB
EGAF00003941859 fq.gz 226.1 MB
EGAF00003941860 fq.gz 238.4 MB
EGAF00003941861 fq.gz 704.4 MB
EGAF00003941862 fq.gz 795.2 MB
EGAF00003941863 fq.gz 294.2 MB
EGAF00003941864 fq.gz 309.2 MB
EGAF00003941865 fq.gz 692.8 MB
EGAF00003941866 fq.gz 791.7 MB
EGAF00003941867 fq.gz 298.7 MB
EGAF00003941868 fq.gz 313.4 MB
EGAF00003941869 fq.gz 575.4 MB
EGAF00003941870 fq.gz 659.1 MB
EGAF00003941871 fq.gz 298.7 MB
EGAF00003941872 fq.gz 320.3 MB
EGAF00003941873 fq.gz 498.1 MB
EGAF00003941874 fq.gz 565.2 MB
EGAF00003941875 fq.gz 228.6 MB
EGAF00003941876 fq.gz 245.2 MB
EGAF00003941877 fq.gz 491.7 MB
EGAF00003941878 fq.gz 550.1 MB
EGAF00003941879 fq.gz 296.2 MB
EGAF00003941880 fq.gz 316.3 MB
EGAF00003941881 fq.gz 550.6 MB
EGAF00003941882 fq.gz 627.1 MB
EGAF00003941883 fq.gz 300.4 MB
EGAF00003941884 fq.gz 320.4 MB
EGAF00003941885 fq.gz 528.3 MB
EGAF00003941886 fq.gz 602.3 MB
EGAF00003941887 fq.gz 296.4 MB
EGAF00003941888 fq.gz 316.4 MB
EGAF00003941889 fq.gz 562.3 MB
EGAF00003941890 fq.gz 640.8 MB
EGAF00003941891 fq.gz 226.7 MB
EGAF00003941892 fq.gz 241.9 MB
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EGAF00003941902 fq.gz 574.2 MB
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EGAF00003941904 fq.gz 334.2 MB
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EGAF00003941906 fq.gz 653.5 MB
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EGAF00003941917 fq.gz 573.9 MB
EGAF00003941918 fq.gz 656.1 MB
EGAF00003941919 fq.gz 338.8 MB
EGAF00003941920 fq.gz 368.1 MB
EGAF00003941921 fq.gz 582.2 MB
EGAF00003941922 fq.gz 662.3 MB
EGAF00003941923 fq.gz 259.2 MB
EGAF00003941924 fq.gz 281.5 MB
EGAF00003941925 fq.gz 587.0 MB
EGAF00003941926 fq.gz 653.1 MB
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EGAF00003941928 fq.gz 364.0 MB
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EGAF00003941930 fq.gz 638.7 MB
EGAF00003941931 fq.gz 343.9 MB
EGAF00003941932 fq.gz 371.4 MB
EGAF00003941933 fq.gz 609.8 MB
EGAF00003941934 fq.gz 695.9 MB
EGAF00003941935 fq.gz 307.4 MB
EGAF00003941936 fq.gz 330.4 MB
EGAF00003941937 fq.gz 558.9 MB
EGAF00003941938 fq.gz 634.9 MB
EGAF00003941939 fq.gz 234.9 MB
EGAF00003941940 fq.gz 252.1 MB
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EGAF00003941944 fq.gz 325.2 MB
EGAF00003941945 fq.gz 625.1 MB
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EGAF00003941949 fq.gz 525.8 MB
EGAF00003941950 fq.gz 586.3 MB
EGAF00003941951 fq.gz 290.3 MB
EGAF00003941952 fq.gz 306.6 MB
EGAF00003941953 fq.gz 649.6 MB
EGAF00003941954 fq.gz 755.0 MB
EGAF00003941955 fq.gz 221.5 MB
EGAF00003941956 fq.gz 233.5 MB
EGAF00003941957 fq.gz 635.2 MB
EGAF00003941958 fq.gz 729.8 MB
EGAF00003941959 fq.gz 288.0 MB
EGAF00003941960 fq.gz 302.1 MB
EGAF00003941961 fq.gz 577.8 MB
EGAF00003941962 fq.gz 668.8 MB
EGAF00003941963 fq.gz 292.3 MB
EGAF00003941964 fq.gz 306.2 MB
EGAF00003941965 fq.gz 569.1 MB
EGAF00003941966 fq.gz 657.1 MB
EGAF00003941967 fq.gz 319.8 MB
EGAF00003941968 fq.gz 345.9 MB
EGAF00003941969 fq.gz 510.2 MB
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1180 Files (879.2 GB)