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RNA sequencing of human intra- and extracranial endothelial cells

This data set contains the raw .fastq files from one RNA-sequencing experiment. Endothelial cells of the basilar artery and endothelial cells of the carotid artery were post-mortem derived with laser microdissection and sequenced. For this analysis both the basilar- and the carotid artery endothelial cells of eleven individuals were sequenced. For more details please see: DMA Hermkens et al. "Profiling the Unique Protective Properties of Intracranial Arterial Endothelial Cells" Acta Neuropathol Commun. 2019 Oct 14; PMID: 31610812.

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Policy for use of data published in PMID: 31610812

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom the DAC grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: The DAC and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III; In any publications based on these data, please describe how the data can be accessed, including the name of the hosting database (e.g., The European Genome-phenome Archive at the European Bioinformatics Institute) and its accession numbers, please also cite the original paper for which this data was generated for. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify the DAC within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify the DAC prior to any significant changes to the protocol for the Project. 14. The User Institution will notify the DAC as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. The DAC may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than the DAC. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and by the laws of the Netherlands and shall be subject to the exclusive jurisdiction of the Netherlands courts.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001004479 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00004039578 fastq.gz 214.9 MB
EGAF00004039579 fastq.gz 219.0 MB
EGAF00004039580 fastq.gz 216.7 MB
EGAF00004039581 fastq.gz 221.6 MB
EGAF00004039582 fastq.gz 52.1 MB
EGAF00004039583 fastq.gz 1.4 MB
EGAF00004039584 fastq.gz 61.3 MB
EGAF00004039585 fastq.gz 61.2 MB
EGAF00004039586 fastq.gz 21.2 MB
EGAF00004039587 fastq.gz 30.7 MB
EGAF00004039588 fastq.gz 20.6 MB
EGAF00004039589 fastq.gz 28.7 MB
EGAF00004039590 fastq.gz 369.9 MB
EGAF00004039591 fastq.gz 375.3 MB
EGAF00004039592 fastq.gz 373.0 MB
EGAF00004039593 fastq.gz 380.1 MB
EGAF00004039594 fastq.gz 27.6 MB
EGAF00004039595 fastq.gz 727.9 kB
EGAF00004039596 fastq.gz 32.9 MB
EGAF00004039597 fastq.gz 32.9 MB
EGAF00004039598 fastq.gz 36.5 MB
EGAF00004039599 fastq.gz 54.2 MB
EGAF00004039600 fastq.gz 36.0 MB
EGAF00004039601 fastq.gz 50.7 MB
EGAF00004039602 fastq.gz 265.6 MB
EGAF00004039603 fastq.gz 270.6 MB
EGAF00004039604 fastq.gz 268.0 MB
EGAF00004039605 fastq.gz 273.4 MB
EGAF00004039606 fastq.gz 38.7 MB
EGAF00004039607 fastq.gz 1.0 MB
EGAF00004039608 fastq.gz 45.0 MB
EGAF00004039609 fastq.gz 46.1 MB
EGAF00004039610 fastq.gz 27.4 MB
EGAF00004039611 fastq.gz 39.7 MB
EGAF00004039612 fastq.gz 26.9 MB
EGAF00004039613 fastq.gz 37.2 MB
EGAF00004039614 fastq.gz 193.9 MB
EGAF00004039615 fastq.gz 197.4 MB
EGAF00004039616 fastq.gz 195.6 MB
EGAF00004039617 fastq.gz 199.7 MB
EGAF00004039618 fastq.gz 44.7 MB
EGAF00004039619 fastq.gz 1.2 MB
EGAF00004039620 fastq.gz 53.5 MB
EGAF00004039621 fastq.gz 54.3 MB
EGAF00004039622 fastq.gz 20.5 MB
EGAF00004039623 fastq.gz 28.8 MB
EGAF00004039624 fastq.gz 20.0 MB
EGAF00004039625 fastq.gz 27.2 MB
EGAF00004039626 fastq.gz 178.1 MB
EGAF00004039627 fastq.gz 179.9 MB
EGAF00004039628 fastq.gz 179.2 MB
EGAF00004039629 fastq.gz 181.8 MB
EGAF00004039630 fastq.gz 41.3 MB
EGAF00004039631 fastq.gz 2.2 MB
EGAF00004039632 fastq.gz 49.1 MB
EGAF00004039633 fastq.gz 49.0 MB
EGAF00004039634 fastq.gz 18.3 MB
EGAF00004039635 fastq.gz 26.1 MB
EGAF00004039636 fastq.gz 17.9 MB
EGAF00004039637 fastq.gz 24.5 MB
EGAF00004039638 fastq.gz 214.3 MB
EGAF00004039639 fastq.gz 219.1 MB
EGAF00004039640 fastq.gz 215.8 MB
EGAF00004039641 fastq.gz 220.9 MB
EGAF00004039642 fastq.gz 51.2 MB
EGAF00004039643 fastq.gz 1.4 MB
EGAF00004039644 fastq.gz 61.1 MB
EGAF00004039645 fastq.gz 60.9 MB
EGAF00004039646 fastq.gz 21.5 MB
EGAF00004039647 fastq.gz 31.5 MB
EGAF00004039648 fastq.gz 21.1 MB
EGAF00004039649 fastq.gz 29.3 MB
EGAF00004039650 fastq.gz 234.8 MB
EGAF00004039651 fastq.gz 240.2 MB
EGAF00004039652 fastq.gz 237.0 MB
EGAF00004039653 fastq.gz 243.1 MB
EGAF00004039654 fastq.gz 55.5 MB
EGAF00004039655 fastq.gz 8.0 MB
EGAF00004039656 fastq.gz 66.7 MB
EGAF00004039657 fastq.gz 66.8 MB
EGAF00004039658 fastq.gz 22.8 MB
EGAF00004039659 fastq.gz 33.8 MB
EGAF00004039660 fastq.gz 22.1 MB
EGAF00004039661 fastq.gz 31.3 MB
EGAF00004039662 fastq.gz 282.4 MB
EGAF00004039663 fastq.gz 288.0 MB
EGAF00004039664 fastq.gz 284.5 MB
EGAF00004039665 fastq.gz 291.7 MB
EGAF00004039666 fastq.gz 68.7 MB
EGAF00004039667 fastq.gz 6.0 MB
EGAF00004039668 fastq.gz 80.6 MB
EGAF00004039669 fastq.gz 81.0 MB
EGAF00004039670 fastq.gz 30.1 MB
EGAF00004039671 fastq.gz 43.6 MB
EGAF00004039672 fastq.gz 29.3 MB
EGAF00004039673 fastq.gz 40.9 MB
EGAF00004039674 fastq.gz 172.1 MB
EGAF00004039675 fastq.gz 175.1 MB
EGAF00004039676 fastq.gz 173.2 MB
EGAF00004039677 fastq.gz 177.1 MB
EGAF00004039678 fastq.gz 41.5 MB
EGAF00004039679 fastq.gz 3.6 MB
EGAF00004039680 fastq.gz 48.6 MB
EGAF00004039681 fastq.gz 48.9 MB
EGAF00004039682 fastq.gz 18.2 MB
EGAF00004039683 fastq.gz 26.2 MB
EGAF00004039684 fastq.gz 17.8 MB
EGAF00004039685 fastq.gz 24.5 MB
EGAF00004039686 fastq.gz 214.4 MB
EGAF00004039687 fastq.gz 218.7 MB
EGAF00004039688 fastq.gz 216.0 MB
EGAF00004039689 fastq.gz 220.5 MB
EGAF00004039690 fastq.gz 51.6 MB
EGAF00004039691 fastq.gz 4.5 MB
EGAF00004039692 fastq.gz 60.9 MB
EGAF00004039693 fastq.gz 60.9 MB
EGAF00004039694 fastq.gz 22.6 MB
EGAF00004039695 fastq.gz 32.0 MB
EGAF00004039696 fastq.gz 22.2 MB
EGAF00004039697 fastq.gz 30.0 MB
EGAF00004039698 fastq.gz 209.9 MB
EGAF00004039699 fastq.gz 213.9 MB
EGAF00004039700 fastq.gz 211.6 MB
EGAF00004039701 fastq.gz 216.5 MB
EGAF00004039702 fastq.gz 50.5 MB
EGAF00004039703 fastq.gz 4.4 MB
EGAF00004039704 fastq.gz 59.9 MB
EGAF00004039705 fastq.gz 60.1 MB
EGAF00004039706 fastq.gz 21.4 MB
EGAF00004039707 fastq.gz 31.5 MB
EGAF00004039708 fastq.gz 21.0 MB
EGAF00004039709 fastq.gz 29.3 MB
EGAF00004039710 fastq.gz 261.1 MB
EGAF00004039711 fastq.gz 265.5 MB
EGAF00004039712 fastq.gz 263.2 MB
EGAF00004039713 fastq.gz 268.4 MB
EGAF00004039714 fastq.gz 60.7 MB
EGAF00004039715 fastq.gz 3.1 MB
EGAF00004039716 fastq.gz 72.3 MB
EGAF00004039717 fastq.gz 72.4 MB
EGAF00004039718 fastq.gz 26.7 MB
EGAF00004039719 fastq.gz 38.7 MB
EGAF00004039720 fastq.gz 26.0 MB
EGAF00004039721 fastq.gz 36.2 MB
EGAF00004039722 fastq.gz 221.4 MB
EGAF00004039723 fastq.gz 225.6 MB
EGAF00004039724 fastq.gz 223.1 MB
EGAF00004039725 fastq.gz 228.2 MB
EGAF00004039726 fastq.gz 53.2 MB
EGAF00004039727 fastq.gz 4.6 MB
EGAF00004039728 fastq.gz 62.8 MB
EGAF00004039729 fastq.gz 63.2 MB
EGAF00004039730 fastq.gz 23.7 MB
EGAF00004039731 fastq.gz 33.9 MB
EGAF00004039732 fastq.gz 23.1 MB
EGAF00004039733 fastq.gz 31.8 MB
EGAF00004039734 fastq.gz 274.3 MB
EGAF00004039735 fastq.gz 278.6 MB
EGAF00004039736 fastq.gz 276.6 MB
EGAF00004039737 fastq.gz 282.0 MB
EGAF00004039738 fastq.gz 40.3 MB
EGAF00004039739 fastq.gz 2.1 MB
EGAF00004039740 fastq.gz 47.8 MB
EGAF00004039741 fastq.gz 47.9 MB
EGAF00004039742 fastq.gz 28.2 MB
EGAF00004039743 fastq.gz 40.9 MB
EGAF00004039744 fastq.gz 27.6 MB
EGAF00004039745 fastq.gz 38.2 MB
EGAF00004039746 fastq.gz 260.7 MB
EGAF00004039747 fastq.gz 265.5 MB
EGAF00004039748 fastq.gz 262.7 MB
EGAF00004039749 fastq.gz 268.1 MB
EGAF00004039750 fastq.gz 61.4 MB
EGAF00004039751 fastq.gz 1.6 MB
EGAF00004039752 fastq.gz 72.9 MB
EGAF00004039753 fastq.gz 73.0 MB
EGAF00004039754 fastq.gz 26.4 MB
EGAF00004039755 fastq.gz 38.6 MB
EGAF00004039756 fastq.gz 25.8 MB
EGAF00004039757 fastq.gz 35.9 MB
EGAF00004039758 fastq.gz 285.2 MB
EGAF00004039759 fastq.gz 290.8 MB
EGAF00004039760 fastq.gz 286.8 MB
EGAF00004039761 fastq.gz 293.7 MB
EGAF00004039762 fastq.gz 68.6 MB
EGAF00004039763 fastq.gz 5.9 MB
EGAF00004039764 fastq.gz 81.2 MB
EGAF00004039765 fastq.gz 81.1 MB
EGAF00004039766 fastq.gz 29.9 MB
EGAF00004039767 fastq.gz 42.7 MB
EGAF00004039768 fastq.gz 29.2 MB
EGAF00004039769 fastq.gz 40.1 MB
EGAF00004039770 fastq.gz 180.0 MB
EGAF00004039771 fastq.gz 181.3 MB
EGAF00004039772 fastq.gz 181.2 MB
EGAF00004039773 fastq.gz 183.8 MB
EGAF00004039774 fastq.gz 43.9 MB
EGAF00004039775 fastq.gz 2.2 MB
EGAF00004039776 fastq.gz 51.0 MB
EGAF00004039777 fastq.gz 50.9 MB
EGAF00004039778 fastq.gz 18.1 MB
EGAF00004039779 fastq.gz 25.5 MB
EGAF00004039780 fastq.gz 17.9 MB
EGAF00004039781 fastq.gz 24.0 MB
EGAF00004039782 fastq.gz 253.9 MB
EGAF00004039783 fastq.gz 258.4 MB
EGAF00004039784 fastq.gz 255.4 MB
EGAF00004039785 fastq.gz 260.8 MB
EGAF00004039786 fastq.gz 60.9 MB
EGAF00004039787 fastq.gz 5.2 MB
EGAF00004039788 fastq.gz 71.6 MB
EGAF00004039789 fastq.gz 71.6 MB
EGAF00004039790 fastq.gz 26.4 MB
EGAF00004039791 fastq.gz 37.8 MB
EGAF00004039792 fastq.gz 25.8 MB
EGAF00004039793 fastq.gz 35.3 MB
EGAF00004039794 fastq.gz 197.8 MB
EGAF00004039795 fastq.gz 202.1 MB
EGAF00004039796 fastq.gz 198.5 MB
EGAF00004039797 fastq.gz 203.6 MB
EGAF00004039798 fastq.gz 48.8 MB
EGAF00004039799 fastq.gz 1.3 MB
EGAF00004039800 fastq.gz 56.0 MB
EGAF00004039801 fastq.gz 56.3 MB
EGAF00004039802 fastq.gz 20.1 MB
EGAF00004039803 fastq.gz 29.1 MB
EGAF00004039804 fastq.gz 19.7 MB
EGAF00004039805 fastq.gz 27.0 MB
EGAF00004039806 fastq.gz 206.9 MB
EGAF00004039807 fastq.gz 212.7 MB
EGAF00004039808 fastq.gz 208.9 MB
EGAF00004039809 fastq.gz 213.8 MB
EGAF00004039810 fastq.gz 46.9 MB
EGAF00004039811 fastq.gz 6.5 MB
EGAF00004039812 fastq.gz 56.5 MB
EGAF00004039813 fastq.gz 56.7 MB
EGAF00004039814 fastq.gz 15.7 MB
EGAF00004039815 fastq.gz 23.6 MB
EGAF00004039816 fastq.gz 15.4 MB
EGAF00004039817 fastq.gz 21.9 MB
EGAF00004039818 fastq.gz 221.1 MB
EGAF00004039819 fastq.gz 224.4 MB
EGAF00004039820 fastq.gz 221.2 MB
EGAF00004039821 fastq.gz 226.5 MB
EGAF00004039822 fastq.gz 54.0 MB
EGAF00004039823 fastq.gz 2.5 MB
EGAF00004039824 fastq.gz 61.1 MB
EGAF00004039825 fastq.gz 62.0 MB
EGAF00004039826 fastq.gz 22.4 MB
EGAF00004039827 fastq.gz 32.5 MB
EGAF00004039828 fastq.gz 22.0 MB
EGAF00004039829 fastq.gz 30.2 MB
EGAF00004039830 fastq.gz 256.8 MB
EGAF00004039831 fastq.gz 262.9 MB
EGAF00004039832 fastq.gz 258.5 MB
EGAF00004039833 fastq.gz 265.2 MB
EGAF00004039834 fastq.gz 59.7 MB
EGAF00004039835 fastq.gz 2.9 MB
EGAF00004039836 fastq.gz 71.0 MB
EGAF00004039837 fastq.gz 70.8 MB
EGAF00004039838 fastq.gz 20.3 MB
EGAF00004039839 fastq.gz 30.7 MB
EGAF00004039840 fastq.gz 19.9 MB
EGAF00004039841 fastq.gz 28.3 MB
264 Files (27.3 GB)