About file location

As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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The Transcriptional Landscape of SHH Medulloblastoma

To further understand the biology of Sonic hedgehog medulloblastoma and its molecular subtypes, we studied 250 human Shh-MB using strand-specific RNA sequencing. We identified novel alterations within the cAMP dependent pathway and found that 18% of tumors have genetic events that directly target the abundance and/or stability of MYCN. We also discovered an extensive network of fusions in focally amplified regions, and several loss-of-function fusions in tumor suppressor genes PTCH, SUFU and NCOR1. Molecular convergence on a core of specific genes by nucleotide variants, copy number aberrations, and gene fusions highlights key roles of specific pathways in the pathogenesis of Sonic hedgehog medulloblastoma.

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DUO:0000006
version: 2019-01-07

health or medical or biomedical research

This data use permission indicates that use is allowed for health/medical/biomedical purposes; does not include the study of population origins or ancestry.

DUO:0000012
version: 2019-01-07

research specific restrictions

This data use modifier indicates that use is limited to studies of a certain research type.

DUO:0000014
version: 2019-01-07

research use only

This data use limitation indicates that use is limited to research purposes (e.g., does not include its use in clinical care).

DUO:0000018
version: 2019-01-07

not for profit, non commercial use only

This data use modifier indicates that use of the data is limited to not-for-profit organizations and not-for-profit use, non-commercial use.

DUO:0000026
version: 2019-01-07

user specific restriction

This data use modifier indicates that use is limited to use by approved users.

DUO:0000027
version: 2019-01-07

project specific restriction

This data use modifier indicates that use is limited to use within an approved project.

DUO:0000028
version: 2019-01-07

institution specific restriction

This data use modifier indicates that use is limited to use within an approved institution.

Genotype/expression array/sequence data generated by MDT lab in Hospital for Sick Children

To access Controlled Access data, please contact us.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001000273 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF00002218097 fastq.gz 8.2 GB Report
EGAF00002218098 fastq.gz 8.4 GB Report
EGAF00004953908 fastq.gz 10.5 GB Report
EGAF00004953909 fastq.gz 10.9 GB Report
EGAF00004953910 fastq.gz 9.3 GB Report
EGAF00004953911 fastq.gz 9.9 GB Report
EGAF00004953912 fastq.gz 7.7 GB Report
EGAF00004953913 fastq.gz 8.2 GB Report
EGAF00004953914 fastq.gz 10.4 GB Report
EGAF00004953915 fastq.gz 10.8 GB Report
EGAF00004953916 fastq.gz 9.7 GB Report
EGAF00004953917 fastq.gz 9.9 GB Report
EGAF00004953918 fastq.gz 9.0 GB Report
EGAF00004953919 fastq.gz 10.1 GB Report
EGAF00004953920 fastq.gz 12.8 GB Report
EGAF00004953921 fastq.gz 13.3 GB Report
EGAF00004953922 fastq.gz 11.3 GB Report
EGAF00004953923 fastq.gz 11.6 GB Report
EGAF00004953924 fastq.gz 7.2 GB Report
EGAF00004953925 fastq.gz 7.4 GB Report
EGAF00004953926 fastq.gz 10.2 GB Report
EGAF00004953927 fastq.gz 10.4 GB Report
EGAF00004953928 fastq.gz 5.7 GB Report
EGAF00004953929 fastq.gz 6.1 GB Report
EGAF00004953930 fastq.gz 7.8 GB Report
EGAF00004953931 fastq.gz 8.5 GB Report
EGAF00004953932 fastq.gz 6.8 GB Report
EGAF00004953933 fastq.gz 7.0 GB Report
EGAF00004953934 fastq.gz 10.4 GB Report
EGAF00004953935 fastq.gz 10.7 GB Report
EGAF00004953936 fastq.gz 9.6 GB Report
EGAF00004953937 fastq.gz 9.8 GB Report
EGAF00004953938 fastq.gz 9.9 GB Report
EGAF00004953939 fastq.gz 10.4 GB Report
EGAF00004953940 fastq.gz 9.6 GB Report
EGAF00004953941 fastq.gz 10.0 GB Report
EGAF00004953942 fastq.gz 10.0 GB Report
EGAF00004953943 fastq.gz 10.4 GB Report
EGAF00004953944 fastq.gz 9.3 GB Report
EGAF00004953945 fastq.gz 9.7 GB Report
EGAF00004953946 fastq.gz 9.5 GB Report
EGAF00004953947 fastq.gz 9.8 GB Report
EGAF00004953948 fastq.gz 8.6 GB Report
EGAF00004953949 fastq.gz 8.7 GB Report
EGAF00004953950 fastq.gz 9.7 GB Report
EGAF00004953951 fastq.gz 9.9 GB Report
EGAF00004953952 fastq.gz 15.8 GB Report
EGAF00004953953 fastq.gz 16.1 GB Report
EGAF00004953954 fastq.gz 9.8 GB Report
EGAF00004953955 fastq.gz 9.9 GB Report
EGAF00004953956 fastq.gz 23.9 GB Report
EGAF00004953957 fastq.gz 23.9 GB Report
EGAF00004953958 fastq.gz 11.3 GB Report
EGAF00004953959 fastq.gz 11.7 GB Report
EGAF00004953960 fastq.gz 11.5 GB Report
EGAF00004953961 fastq.gz 11.9 GB Report
EGAF00004953962 fastq.gz 10.4 GB Report
EGAF00004953963 fastq.gz 10.8 GB Report
EGAF00004953964 fastq.gz 10.9 GB Report
EGAF00004953965 fastq.gz 11.2 GB Report
EGAF00004953966 fastq.gz 9.8 GB Report
EGAF00004953967 fastq.gz 10.2 GB Report
EGAF00004953968 fastq.gz 9.1 GB Report
EGAF00004953969 fastq.gz 9.2 GB Report
EGAF00004953970 fastq.gz 8.2 GB Report
EGAF00004953971 fastq.gz 8.1 GB Report
EGAF00004953972 fastq.gz 13.1 GB Report
EGAF00004953973 fastq.gz 12.9 GB Report
EGAF00004953974 fastq.gz 10.2 GB Report
EGAF00004953975 fastq.gz 10.2 GB Report
EGAF00004953976 fastq.gz 10.5 GB Report
EGAF00004953977 fastq.gz 10.5 GB Report
EGAF00004953978 fastq.gz 9.3 GB Report
EGAF00004953979 fastq.gz 9.4 GB Report
EGAF00004953980 fastq.gz 10.5 GB Report
EGAF00004953981 fastq.gz 10.6 GB Report
EGAF00004953982 fastq.gz 9.1 GB Report
EGAF00004953983 fastq.gz 9.1 GB Report
EGAF00004953984 fastq.gz 11.7 GB Report
EGAF00004953985 fastq.gz 11.8 GB Report
EGAF00004953986 fastq.gz 9.7 GB Report
EGAF00004953987 fastq.gz 9.6 GB Report
EGAF00004953988 fastq.gz 11.6 GB Report
EGAF00004953989 fastq.gz 11.5 GB Report
EGAF00004953990 fastq.gz 12.0 GB Report
EGAF00004953991 fastq.gz 12.1 GB Report
EGAF00004953992 fastq.gz 8.8 GB Report
EGAF00004953993 fastq.gz 8.8 GB Report
EGAF00004953994 fastq.gz 9.6 GB Report
EGAF00004953995 fastq.gz 9.6 GB Report
EGAF00004953996 fastq.gz 9.6 GB Report
EGAF00004953997 fastq.gz 9.7 GB Report
EGAF00004953998 fastq.gz 10.4 GB Report
EGAF00004953999 fastq.gz 10.4 GB Report
EGAF00004954000 fastq.gz 8.5 GB Report
EGAF00004954001 fastq.gz 8.5 GB Report
EGAF00004954002 fastq.gz 10.0 GB Report
EGAF00004954003 fastq.gz 10.1 GB Report
EGAF00004954004 fastq.gz 10.8 GB Report
EGAF00004954005 fastq.gz 10.8 GB Report
EGAF00004954006 fastq.gz 8.8 GB Report
EGAF00004954007 fastq.gz 8.9 GB Report
EGAF00004954008 fastq.gz 9.4 GB Report
EGAF00004954009 fastq.gz 9.3 GB Report
EGAF00004954010 fastq.gz 9.3 GB Report
EGAF00004954011 fastq.gz 9.3 GB Report
EGAF00004954012 fastq.gz 12.1 GB Report
EGAF00004954013 fastq.gz 12.2 GB Report
EGAF00004954014 fastq.gz 9.0 GB Report
EGAF00004954015 fastq.gz 9.0 GB Report
EGAF00004954016 fastq.gz 11.4 GB Report
EGAF00004954017 fastq.gz 11.4 GB Report
EGAF00004954018 fastq.gz 9.8 GB Report
EGAF00004954019 fastq.gz 9.8 GB Report
EGAF00004954020 fastq.gz 9.0 GB Report
EGAF00004954021 fastq.gz 9.0 GB Report
EGAF00004954022 fastq.gz 6.7 GB Report
EGAF00004954023 fastq.gz 6.7 GB Report
EGAF00004954024 fastq.gz 8.3 GB Report
EGAF00004954025 fastq.gz 8.5 GB Report
EGAF00004954026 fastq.gz 11.6 GB Report
EGAF00004954027 fastq.gz 11.2 GB Report
EGAF00004954028 fastq.gz 10.0 GB Report
EGAF00004954029 fastq.gz 10.0 GB Report
EGAF00004954030 fastq.gz 10.4 GB Report
EGAF00004954031 fastq.gz 10.4 GB Report
EGAF00004954032 fastq.gz 11.7 GB Report
EGAF00004954033 fastq.gz 11.8 GB Report
EGAF00004954034 fastq.gz 10.6 GB Report
EGAF00004954035 fastq.gz 10.6 GB Report
EGAF00004954036 fastq.gz 9.6 GB Report
EGAF00004954037 fastq.gz 9.6 GB Report
EGAF00004954038 fastq.gz 7.9 GB Report
EGAF00004954039 fastq.gz 7.9 GB Report
EGAF00004954040 fastq.gz 10.9 GB Report
EGAF00004954041 fastq.gz 11.1 GB Report
EGAF00004954042 fastq.gz 11.2 GB Report
EGAF00004954043 fastq.gz 11.4 GB Report
EGAF00004954044 fastq.gz 10.0 GB Report
EGAF00004954045 fastq.gz 10.0 GB Report
EGAF00004954046 fastq.gz 13.7 GB Report
EGAF00004954047 fastq.gz 13.8 GB Report
EGAF00004954048 fastq.gz 9.7 GB Report
EGAF00004954049 fastq.gz 10.0 GB Report
EGAF00004954050 fastq.gz 10.7 GB Report
EGAF00004954051 fastq.gz 10.4 GB Report
EGAF00004954052 fastq.gz 11.1 GB Report
EGAF00004954053 fastq.gz 11.2 GB Report
EGAF00004954054 fastq.gz 13.2 GB Report
EGAF00004954055 fastq.gz 13.4 GB Report
EGAF00004954056 fastq.gz 8.0 GB Report
EGAF00004954057 fastq.gz 7.9 GB Report
EGAF00004954058 fastq.gz 12.7 GB Report
EGAF00004954059 fastq.gz 12.8 GB Report
EGAF00004954060 fastq.gz 8.6 GB Report
EGAF00004954061 fastq.gz 8.6 GB Report
EGAF00004954062 fastq.gz 9.6 GB Report
EGAF00004954063 fastq.gz 9.6 GB Report
EGAF00004954064 fastq.gz 9.3 GB Report
EGAF00004954065 fastq.gz 9.5 GB Report
EGAF00004954066 fastq.gz 7.9 GB Report
EGAF00004954067 fastq.gz 7.9 GB Report
EGAF00004954068 fastq.gz 9.8 GB Report
EGAF00004954069 fastq.gz 9.8 GB Report
164 Files (1.7 TB)