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INSPIRE RNA-seq tumors

INSPIRE whole transcriptome sequencing of tumors

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Access to data generated by UHN is made available by completing the data access agreement for review by the data access committee and will be granted to qualified investigators for appropriate use.

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom the Data Access Committee (DAC) grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: The Principal Investigator and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. University Health Network: The University Health Network (UHN) is the largest clinical and research hospital in Canada. UHN is affiliated with the University of Toronto and is a member of the Toronto Academic Health Science Network. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify the DAC within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify the DAC prior to any significant changes to the protocol for the Project. 14. The User Institution will notify the DAC as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. The DAC may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of the province of Ontario and PHIPA. Agreed for User Institution Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for The Data Access Committee Signature: Name: Title: Date: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001003280 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00004835338 bam 10.7 GB
EGAF00004835339 bam 14.7 GB
EGAF00004835340 bam 11.3 GB
EGAF00004835341 bam 16.9 GB
EGAF00004835342 bam 17.8 GB
EGAF00004835343 bam 21.9 GB
EGAF00004835344 bam 20.0 GB
EGAF00004835345 bam 20.9 GB
EGAF00004835346 bam 20.9 GB
EGAF00004835347 bam 20.2 GB
EGAF00004835348 bam 18.7 GB
EGAF00004835349 bam 18.4 GB
EGAF00004835350 bam 16.0 GB
EGAF00004835351 bam 19.6 GB
EGAF00004835352 bam 19.0 GB
EGAF00004835353 bam 17.4 GB
EGAF00004835354 bam 17.0 GB
EGAF00004835355 bam 16.2 GB
EGAF00004835356 bam 16.4 GB
EGAF00004835357 bam 20.8 GB
EGAF00004835358 bam 14.7 GB
EGAF00004835359 bam 11.7 GB
EGAF00004835360 bam 19.2 GB
EGAF00004835361 bam 17.2 GB
EGAF00004835362 bam 12.0 GB
EGAF00004835363 bam 10.6 GB
EGAF00004835364 bam 12.9 GB
EGAF00004835365 bam 8.7 GB
EGAF00004835366 bam 11.7 GB
EGAF00004835367 bam 13.0 GB
EGAF00004835368 bam 18.5 GB
EGAF00004835369 bam 15.0 GB
EGAF00004835370 bam 19.6 GB
EGAF00004835371 bam 16.7 GB
EGAF00004835372 bam 16.9 GB
EGAF00004835373 bam 15.6 GB
EGAF00004835374 bam 17.8 GB
EGAF00004835375 bam 12.3 GB
EGAF00004835376 bam 19.3 GB
EGAF00004835377 bam 16.3 GB
EGAF00004835378 bam 21.2 GB
EGAF00004835379 bam 19.5 GB
EGAF00004835380 bam 17.7 GB
EGAF00004835381 bam 20.6 GB
EGAF00004835382 bam 16.9 GB
EGAF00004835383 bam 10.8 GB
EGAF00004835384 bam 19.9 GB
EGAF00004835385 bam 40.2 GB
EGAF00004835386 bam 16.3 GB
EGAF00004835387 bam 23.4 GB
EGAF00004835388 bam 15.6 GB
EGAF00004835389 bam 18.8 GB
EGAF00004835390 bam 20.2 GB
EGAF00004835391 bam 16.2 GB
EGAF00004835392 bam 17.9 GB
EGAF00004835393 bam 16.7 GB
EGAF00004835394 bam 21.0 GB
EGAF00004835395 bam 15.9 GB
EGAF00004835396 bam 18.2 GB
EGAF00004835397 bam 17.1 GB
EGAF00004835398 bam 7.4 GB
EGAF00004835399 bam 8.8 GB
EGAF00004835400 bam 18.1 GB
EGAF00004835401 bam 20.1 GB
EGAF00004835402 bam 23.7 GB
EGAF00004835403 bam 13.3 GB
EGAF00004835404 bam 17.6 GB
EGAF00004835405 bam 18.3 GB
EGAF00004835406 bam 15.2 GB
EGAF00004835407 bam 21.1 GB
EGAF00004835408 bam 16.5 GB
EGAF00004835409 bam 10.0 GB
EGAF00004835410 bam 22.0 GB
EGAF00004835411 bam 22.1 GB
EGAF00004835412 bam 16.8 GB
EGAF00004835413 bam 12.8 GB
EGAF00004835414 bam 18.8 GB
EGAF00004835415 bam 16.9 GB
EGAF00004835416 bam 19.0 GB
EGAF00004835417 bam 19.8 GB
EGAF00004835418 bam 17.6 GB
EGAF00004835419 bam 15.6 GB
EGAF00004835420 bam 18.9 GB
EGAF00004835421 bam 21.8 GB
EGAF00004835422 bam 20.0 GB
EGAF00004835423 bam 19.4 GB
EGAF00004835424 bam 19.4 GB
EGAF00004835425 bam 18.6 GB
EGAF00004835426 bam 17.0 GB
EGAF00004835427 bam 15.4 GB
EGAF00004835428 bam 18.8 GB
EGAF00004835429 bam 8.0 GB
EGAF00004835430 bam 15.3 GB
EGAF00004835431 bam 16.2 GB
EGAF00004835432 bam 8.6 GB
EGAF00004835433 bam 12.3 GB
EGAF00004835434 bam 29.6 GB
EGAF00004835435 bam 14.5 GB
EGAF00004835436 bam 17.4 GB
EGAF00004835437 bam 14.4 GB
EGAF00004835438 bam 23.2 GB
EGAF00004835439 bam 20.8 GB
EGAF00004835440 bam 26.2 GB
EGAF00004835441 bam 16.8 GB
EGAF00004835442 bam 21.3 GB
EGAF00004835443 bam 11.8 GB
EGAF00004835444 bam 13.7 GB
107 Files (1.8 TB)