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The Precision Medicine in Liver Cancer across an Asia-pacific NETwork (PLANET) - Intratumoural immune heterogeneity

The clinical relevance of immune landscape intratumoural heterogeneity (immune-ITH) and its role in tumour evolution remain largely unexplored. Here, we uncover significant spatial and phenotypic immune–ITH from multiple tumour sectors and decipher its relationship with tumour evolution and disease progression in hepatocellular carcinomas (HCC). Immune–ITH is associated with tumour transcriptomic-ITH, mutational burden, and distinct immune microenvironments. Tumours with low immune–ITH experience higher immunoselective pressure and escape via loss of heterozygosity in human leukocyte antigens and immunoediting. Instead, the tumours with high immune-ITH evolve to a more immunosuppressive/exhausted microenvironment. This gradient of immune pressure along with immune-ITH represents a hallmark of tumour evolution, which is closely linked to the transcriptome-immune networks that contributes to disease progression and immune inactivation. Remarkably, high immune-ITH and its transcriptomic signature are predictive for worse clinical outcome in HCC patients. This in-depth investigation of ITH provides evidence on tumour-immune co-evolution along HCC progression.

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Data access agreement (PLANET)

DATA ACCESS AGREEMENT Data of genomic variant calls and/or raw sequencing data generated by Next Generation Sequencing European Genome-phenome Archive THIS AGREEMENT is made the ______ day of __________ . Between: 1. GenomeInstituteofSingapore, Biomedical Sciences Institutes (Co. Reg. No. 199702109N), having its principal office at 60 Biopolis Street, Genome #02-01, Singapore 138672 (“GIS”); 2. ___________________________________ [Name of Company/Institution] (Co. Reg. No. ___________________), of __________________________________ [Insert address] (“Recipient”); and 3. ____________________________________ [Name of Registered User], of ____________________________________ [Insert address] (“Registered User”) RECITALS (A) GIS is a national research institution based in Singapore and funded by the Agency for Science, Technology And Research (“A*STAR”). (B) The European Genome-phenome Archive (EGA) is designed to be a repository for all types of sequence and genotype experiments, including case-control, population, and family studies. EGA is managed by European Bioinformatics Institute (EBI). (C) The Recipient is a ___________________________________ [Insert description of Recipient] (D) Anonymous data which is stripped of all personal identifiers is collected by GIS and disclosed to the Recipient, for the sole purpose of facilitating academic research conducted solely by the Recipient by providing a means for the Recipient to validate information relevant to its academic, non-commercial research. (E) GIS owns the Data (as defined below) and reserves the absolute discretion to decide whether or not to grant access to the Data. In response to the Recipient’s request for access to the Data, GIS hereby agrees to provide the Data to the Recipient for the sole purpose of the Research upon the terms and conditions hereinafter appearing: 1. DEFINITIONS In this Agreement, unless the context otherwise requires, the following definitions shall apply. ‘Data’ means the data as described in Schedule 1. ‘Data Subject’ means the individual to whom the Data refers to. ‘Intellectual Property’ means (i) patents, designs, trade marks and trade names (whether registered or unregistered), copyright and related rights, database rights; (ii) all other intellectual property rights and similar or equivalent rights anywhere in the world which currently exist or are recognised in the future; and (iii) applications, extensions and renewals in relation to any such rights. ‘PDPA’ means the Republic of Singapore Personal Data Protection Act 2012. ‘Registered User’ means a Researcher (or an individual conducting research under the supervision of a Researcher) that is employed by, or enrolled in, the Recipient and is bound by confidentiality and non-use obligations in respect of the Data and who has signed this Agreement and has received acknowledgement of its acceptance. 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In particular, the Recipient and its Registered Users undertake not to use, or attempt to use, the Data to deliberately compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. 6.3 The Recipient and its Registered Users shall not analyse, make any use of or otherwise subject the Data to any process in such a way that has the potential to lead to the identification of any Data Subject or compromise the anonymity of any Data Subject in any way. In particular, the Recipient and its Registered Users shall not pursue any research with the goal of identifying the Data Subjects or link or combine the Data with other information or archived data available in any way that could re-identify the Data Subjects, even if access to that data has been formally granted to the Recipient or its Registered Users, or is freely available without restriction. 7. 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If GIS deems that the publication will prejudice a patent application or contains information which may compromise personal data, GIS shall within thirty (30) days of the intended publication give notice in writing of any objections they may have to the Recipient and/or the Registered User and the Recipient and/or Registered User shall delay any such publication for a further thirty (30) days from the date of the aforesaid notice from GIS to permit GIS to file the appropriate patent application. 7.3 The Recipient and/or its Registered Users shall also declare in any such work that those who carried out the original analysis and collection of the Data shall bear no responsibility for the further analysis or interpretation of it by the Recipient and/or its Registered User. 8. DATA REISSUE The Recipient and its Registered Users accept that Data will be reissued from time to time, with suitable versioning. 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The Recipient must provide written confirmation of the destruction of the Data received from GIS in accordance with any applicable laws and/or procedures. 11.4 Clauses 6, 7, 9 to 12, 13.1, and 13.2 shall survive the termination of this Agreement howsoever caused. 12. GOVERNING LAW AND JURISDICTION This Agreement shall be construed, governed, interpreted and applied in accordance with the laws of the Republic of Singapore in all respects. 13. GENERAL 13.1 No exercise or failure to exercise or delay in exercising any right, power, or remedy vested in any party under or pursuant to this Agreement shall constitute a waiver by that party of that or any right, power or remedy. 13.2 The parties agree that no person who is not a party to this Agreement shall have any right to enforce any term of this Agreement by virtue of the Contracts (Rights of Third Parties) Act or otherwise. 13.3 The Recipient and its Registered Users accept that it may be necessary for GIS to alter the terms of this Agreement from time to time in order to address new concerns. In this event, GIS will contact the Recipient to inform it of any changes and the Recipient and/or its Registered Users agree that its continued use of the Data shall be dependent on the parties entering into a variation of the Agreement. Amendments to this Agreement must be made in writing and agreed to by both parties. 14. ASSIGNMENT 14.1 If, at any time after the date of this Agreement the functions and operations of GIS are assigned, merged, transferred into or otherwise forms part of another organisation ("the New Entity"), such that the New Entity takes over the whole or substantially the whole of GIS’ operations, then it is agreed that this Agreement may, at the option of GIS, be novated to the New Entity which will then assume all of GIS’ rights and obligations hereunder. It is further agreed that GIS may assign all or any part of its rights hereunder to the New Entity or to any A*STAR Affiliate at nominal consideration. “A*STAR Affiliate” shall mean a national research institute or company within the purview of or funded by the Agency for Science, Technology and Research (or its assign or successor). 14.2 Save as aforesaid, this Agreement is not assignable by either party, whether by operation of law or otherwise, without the prior written consent of the other party. 15. FORCE MAJEURE 15.1 Neither party shall be liable for delays in delivery or performance when caused by any of the following which are beyond the actual control of the delayed party: (i) acts of God, (ii) acts of the public enemy, (iii) acts or failure to act by the other party or by any third party, (iv) acts of civil or military authority, (v) governmental priorities, (vi) hurricanes, (vii) earthquakes, (viii) fires, (ix) floods, (x) epidemics or pandemics, (xi) embargoes, (xii) war, and (xiii) riots (hereinafter referred to as the “Force Majeure Event”). 15.2 The respective obligations of either party hereunder shall be suspended during the time and to the extent that such party is prevented from complying therewith by a Force Majeure Event, provided that such party shall have given written notice thereof, specifying the nature and details of such event and the probable extent of the delay to the other party. 15.3 In case of a Force Majeure Event, the time for performance required by either party under this Agreement shall be extended for any period during which the performance is prevented by the event. However, the other party may terminate this Agreement by notice if such an event prevents performance continuously for more than thirty (30) days. AS WITNESS the hands of the parties hereto the day and year first above written. SIGNED by ) ) for and on behalf of GENOME INSTITUTE OF ) ) SINGAPORE ) ______________________ ) Name: in the presence of: ) Designation: Date: ___________________________ Name of Witness: Designation of Witness: Date: For and on behalf of Recipient _________________________________ Name: Designation: Date: Registered User _________________________________ Name: Designation: Date: SCHEDULE 1 Data The data comprises of genomic variant calls and/or raw sequencing data generated by Next Generation Sequencing (NGS) technologies. SCHEDULE 2 Research SCHEDULE 3 Publications Policy The primary purpose of GIS granting access to the Data to the Recipient and its Registered Users is to facilitate academic research conducted by the Recipient and to provide a means for the Recipient to validate information relevant to its academic, non-commercial research. GIS anticipates that the Data will be used by others. Persons who use the Data must acknowledge GIS using the following wording “This study makes use of data generated by the Genome Institute of Singapore” and cite the relevant primary GIS publication from which the Data was taken. All users of the Data must take note that GIS bears no responsibility for the further analysis or interpretation of the Data.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001003813 Other
EGAS00001003814 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002854369 fastq.gz 4.1 GB
EGAF00002854376 fastq.gz 2.9 GB
EGAF00002854381 fastq.gz 2.7 GB
EGAF00002854383 fastq.gz 4.6 GB
EGAF00002854388 fastq.gz 3.2 GB
EGAF00002854390 fastq.gz 2.9 GB
EGAF00002854395 fastq.gz 3.8 GB
EGAF00002854399 fastq.gz 6.9 GB
EGAF00002854403 fastq.gz 5.3 GB
EGAF00002854406 fastq.gz 4.7 GB
EGAF00002854410 fastq.gz 44.6 GB
EGAF00002854418 fastq.gz 5.3 GB
EGAF00002854423 fastq.gz 6.6 GB
EGAF00002854424 fastq.gz 6.4 GB
EGAF00002854428 fastq.gz 7.2 GB
EGAF00002854431 fastq.gz 5.4 GB
EGAF00002854432 fastq.gz 3.8 GB
EGAF00002854435 fastq.gz 4.8 GB
EGAF00002854440 fastq.gz 7.8 GB
EGAF00002854443 fastq.gz 4.2 GB
EGAF00002854449 fastq.gz 2.7 GB
EGAF00002854453 fastq.gz 6.1 GB
EGAF00002854454 fastq.gz 4.7 GB
EGAF00002854457 fastq.gz 5.3 GB
EGAF00002854464 fastq.gz 6.1 GB
EGAF00002854465 fastq.gz 5.6 GB
EGAF00002854469 fastq.gz 3.3 GB
EGAF00002854471 fastq.gz 51.1 GB
EGAF00002854472 fastq.gz 6.8 GB
EGAF00002854477 fastq.gz 42.7 GB
EGAF00002854480 fastq.gz 5.7 GB
EGAF00002854483 fastq.gz 37.7 GB
EGAF00002854485 fastq.gz 47.0 GB
EGAF00002854488 fastq.gz 7.4 GB
EGAF00002854493 fastq.gz 6.9 GB
EGAF00002854494 fastq.gz 5.0 GB
EGAF00002854499 fastq.gz 3.1 GB
EGAF00002854500 fastq.gz 8.6 GB
EGAF00002854501 fastq.gz 1.4 GB
EGAF00002854503 fastq.gz 7.2 GB
EGAF00002854513 fastq.gz 2.8 GB
EGAF00002854515 fastq.gz 37.8 GB
EGAF00002854517 fastq.gz 4.5 GB
EGAF00002854526 fastq.gz 5.0 GB
EGAF00002854528 fastq.gz 5.1 GB
EGAF00002854534 fastq.gz 2.7 GB
EGAF00002854536 fastq.gz 2.9 GB
EGAF00002854538 fastq.gz 4.3 GB
EGAF00002854539 fastq.gz 5.8 GB
EGAF00002854540 fastq.gz 6.2 GB
EGAF00002854541 fastq.gz 8.4 GB
EGAF00002854548 fastq.gz 6.3 GB
EGAF00002854549 fastq.gz 4.1 GB
EGAF00002854550 fastq.gz 3.0 GB
EGAF00002854554 fastq.gz 6.4 GB
EGAF00002854559 fastq.gz 4.6 GB
EGAF00002854560 fastq.gz 1.4 GB
EGAF00002854563 fastq.gz 6.1 GB
EGAF00002854564 fastq.gz 3.5 GB
EGAF00002854567 fastq.gz 3.3 GB
EGAF00002854575 fastq.gz 4.5 GB
EGAF00002854577 fastq.gz 2.9 GB
EGAF00002854579 fastq.gz 2.4 GB
EGAF00002854580 fastq.gz 3.5 GB
EGAF00002854581 fastq.gz 2.9 GB
EGAF00002854585 fastq.gz 6.4 GB
EGAF00002854586 fastq.gz 6.0 GB
EGAF00002854592 fastq.gz 4.8 GB
EGAF00002854597 fastq.gz 5.3 GB
EGAF00002854599 fastq.gz 7.5 GB
EGAF00002854602 fastq.gz 5.7 GB
EGAF00002854608 fastq.gz 1.4 GB
EGAF00002854610 fastq.gz 3.0 GB
EGAF00002854615 fastq.gz 6.6 GB
EGAF00002854619 fastq.gz 5.9 GB
EGAF00002854621 fastq.gz 7.1 GB
EGAF00002854622 fastq.gz 5.3 GB
EGAF00002854623 fastq.gz 6.7 GB
EGAF00002854630 fastq.gz 6.9 GB
EGAF00002854631 fastq.gz 6.8 GB
EGAF00002854632 fastq.gz 3.1 GB
EGAF00002854634 fastq.gz 6.3 GB
EGAF00002854636 fastq.gz 7.8 GB
EGAF00002854642 fastq.gz 7.4 GB
EGAF00002854647 fastq.gz 6.2 GB
EGAF00002854653 fastq.gz 49.2 GB
EGAF00002854681 fastq.gz 5.2 GB
EGAF00002854684 fastq.gz 29.3 GB
EGAF00002854689 fastq.gz 5.5 GB
EGAF00002854694 fastq.gz 6.4 GB
EGAF00002854705 fastq.gz 4.8 GB
EGAF00002854707 fastq.gz 2.8 GB
EGAF00002854712 fastq.gz 5.7 GB
EGAF00002854715 fastq.gz 3.8 GB
EGAF00002854724 fastq.gz 7.3 GB
EGAF00002854732 fastq.gz 2.9 GB
EGAF00002854745 fastq.gz 3.1 GB
EGAF00002854749 fastq.gz 5.7 GB
EGAF00002854758 fastq.gz 3.9 GB
EGAF00002854762 fastq.gz 2.8 GB
EGAF00002854764 fastq.gz 1.2 GB
EGAF00002854771 fastq.gz 6.1 GB
EGAF00002854775 fastq.gz 4.6 GB
EGAF00002854776 fastq.gz 2.9 GB
EGAF00002854781 fastq.gz 7.0 GB
EGAF00002854784 fastq.gz 6.8 GB
EGAF00002854788 fastq.gz 3.0 GB
EGAF00002854796 fastq.gz 4.0 GB
EGAF00002854798 fastq.gz 2.8 GB
EGAF00002854799 fastq.gz 7.7 GB
EGAF00002854807 fastq.gz 6.3 GB
EGAF00002854809 fastq.gz 4.1 GB
EGAF00002854810 fastq.gz 5.4 GB
EGAF00002854813 fastq.gz 6.1 GB
EGAF00002854814 fastq.gz 5.5 GB
EGAF00002854816 fastq.gz 3.5 GB
EGAF00002854818 fastq.gz 6.6 GB
EGAF00002854839 fastq.gz 866.1 MB
EGAF00002854854 fastq.gz 6.4 GB
EGAF00002854864 fastq.gz 3.1 GB
EGAF00002854877 fastq.gz 5.9 GB
EGAF00002854878 fastq.gz 6.8 GB
EGAF00002854882 fastq.gz 3.8 GB
EGAF00002854883 fastq.gz 9.1 GB
EGAF00002854885 fastq.gz 6.0 GB
EGAF00002854892 fastq.gz 46.6 GB
EGAF00002854894 fastq.gz 52.4 GB
EGAF00002854895 fastq.gz 6.7 GB
EGAF00002854897 fastq.gz 5.6 GB
EGAF00002854898 fastq.gz 6.2 GB
EGAF00002854900 fastq.gz 6.8 GB
EGAF00002854904 fastq.gz 5.1 GB
EGAF00002854908 fastq.gz 2.6 GB
EGAF00002854911 fastq.gz 7.1 GB
EGAF00002854912 fastq.gz 4.7 GB
EGAF00002854914 fastq.gz 4.7 GB
EGAF00002854915 fastq.gz 4.6 GB
EGAF00002854916 fastq.gz 6.5 GB
EGAF00002854920 fastq.gz 8.3 GB
EGAF00002854923 fastq.gz 3.7 GB
EGAF00002854932 fastq.gz 7.1 GB
EGAF00002854937 fastq.gz 50.5 GB
EGAF00002854945 fastq.gz 3.3 GB
EGAF00002854946 fastq.gz 5.8 GB
EGAF00002854950 fastq.gz 5.0 GB
EGAF00002854954 fastq.gz 4.4 GB
EGAF00002854955 fastq.gz 4.2 GB
EGAF00002854959 fastq.gz 4.6 GB
EGAF00002854967 fastq.gz 3.8 GB
EGAF00002854969 fastq.gz 4.9 GB
EGAF00002854974 fastq.gz 55.6 GB
EGAF00002854976 fastq.gz 4.9 GB
EGAF00002854978 fastq.gz 6.7 GB
EGAF00002854979 fastq.gz 3.1 GB
EGAF00002854981 fastq.gz 5.8 GB
EGAF00002854984 fastq.gz 2.9 GB
EGAF00002854985 fastq.gz 3.8 GB
EGAF00002854987 fastq.gz 6.1 GB
EGAF00002854989 fastq.gz 7.2 GB
EGAF00002854991 fastq.gz 4.3 GB
EGAF00002854996 fastq.gz 3.6 GB
EGAF00002854999 fastq.gz 2.4 GB
EGAF00002855000 fastq.gz 45.2 GB
EGAF00002855001 fastq.gz 44.6 GB
EGAF00002855004 fastq.gz 4.1 GB
EGAF00002855005 fastq.gz 3.7 GB
EGAF00002855006 fastq.gz 4.0 GB
EGAF00002855008 fastq.gz 5.7 GB
EGAF00002855010 fastq.gz 50.4 GB
EGAF00002855011 fastq.gz 4.8 GB
EGAF00002855016 fastq.gz 8.5 GB
EGAF00002855018 fastq.gz 4.5 GB
EGAF00002855025 fastq.gz 6.3 GB
EGAF00002855026 fastq.gz 6.5 GB
EGAF00002855028 fastq.gz 3.0 GB
EGAF00002855033 fastq.gz 6.4 GB
EGAF00002855041 fastq.gz 4.5 GB
EGAF00002855045 fastq.gz 7.6 GB
EGAF00002855046 fastq.gz 54.6 GB
EGAF00002855052 fastq.gz 54.0 GB
EGAF00002855057 fastq.gz 2.9 GB
EGAF00002855061 fastq.gz 50.2 GB
EGAF00002855062 fastq.gz 30.1 GB
EGAF00002855066 fastq.gz 49.4 GB
EGAF00002855077 fastq.gz 3.1 GB
EGAF00002855078 fastq.gz 2.9 GB
EGAF00002855081 fastq.gz 6.0 GB
EGAF00002855082 fastq.gz 5.7 GB
EGAF00002855083 fastq.gz 3.7 GB
EGAF00002855085 fastq.gz 7.3 GB
EGAF00002855086 fastq.gz 6.1 GB
EGAF00002855088 fastq.gz 5.8 GB
EGAF00002855090 fastq.gz 3.6 GB
EGAF00002855091 fastq.gz 6.1 GB
EGAF00002855092 fastq.gz 1.6 GB
EGAF00002855093 fastq.gz 6.7 GB
EGAF00002855094 fastq.gz 6.8 GB
EGAF00002855097 fastq.gz 6.8 GB
EGAF00002855099 fastq.gz 3.5 GB
EGAF00002855100 fastq.gz 3.0 GB
EGAF00002855108 fastq.gz 8.3 GB
EGAF00002855109 fastq.gz 13.4 GB
EGAF00002855112 fastq.gz 5.8 GB
EGAF00002855120 fastq.gz 4.1 GB
EGAF00002855121 fastq.gz 2.9 GB
EGAF00002855127 fastq.gz 2.6 GB
EGAF00002855128 fastq.gz 8.5 GB
EGAF00002855131 fastq.gz 52.5 GB
EGAF00002855133 fastq.gz 5.8 GB
EGAF00002855134 fastq.gz 6.2 GB
EGAF00002855139 fastq.gz 34.1 GB
EGAF00002855147 fastq.gz 7.4 GB
EGAF00002855148 fastq.gz 6.0 GB
EGAF00002855149 fastq.gz 9.2 GB
EGAF00002855153 fastq.gz 51.6 GB
EGAF00002855159 fastq.gz 4.7 GB
EGAF00002855161 fastq.gz 6.2 GB
EGAF00002855168 fastq.gz 2.8 GB
EGAF00002855169 fastq.gz 3.7 GB
EGAF00002855180 fastq.gz 3.1 GB
EGAF00002855181 fastq.gz 45.4 GB
EGAF00002855194 fastq.gz 5.2 GB
EGAF00002855195 fastq.gz 4.6 GB
EGAF00002855197 fastq.gz 3.0 GB
EGAF00002855199 fastq.gz 6.3 GB
EGAF00002855201 fastq.gz 5.4 GB
EGAF00002855205 fastq.gz 3.3 GB
EGAF00002855206 fastq.gz 2.7 GB
EGAF00002855212 fastq.gz 6.9 GB
EGAF00002855216 fastq.gz 5.5 GB
EGAF00002855217 fastq.gz 1.6 GB
EGAF00002855219 fastq.gz 7.5 GB
EGAF00002855222 fastq.gz 5.2 GB
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EGAF00004827955 fastq.gz 12.4 GB
EGAF00004827956 fastq.gz 12.2 GB
EGAF00004827957 fastq.gz 12.3 GB
EGAF00004827958 fastq.gz 12.2 GB
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EGAF00004828013 fastq.gz 848.0 MB
EGAF00004828014 fastq.gz 832.7 MB
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EGAF00004828019 fastq.gz 838.3 MB
EGAF00004828020 fastq.gz 826.3 MB
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EGAF00004828025 fastq.gz 847.5 MB
EGAF00004828026 fastq.gz 899.8 MB
EGAF00004828027 fastq.gz 903.1 MB
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EGAF00004828038 fastq.gz 1.7 GB
EGAF00004828039 fastq.gz 1.9 GB
EGAF00004828040 fastq.gz 1.7 GB
EGAF00004828041 fastq.gz 1.9 GB
EGAF00004828042 fastq.gz 1.6 GB
EGAF00004828043 fastq.gz 1.9 GB
EGAF00004828044 fastq.gz 1.7 GB
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EGAF00004828046 fastq.gz 1.5 GB
EGAF00004828047 fastq.gz 1.7 GB
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EGAF00004828049 fastq.gz 1.8 GB
EGAF00004828050 fastq.gz 1.4 GB
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EGAF00004828053 fastq.gz 1.6 GB
EGAF00004828054 fastq.gz 2.9 GB
EGAF00004828055 fastq.gz 3.4 GB
EGAF00004828056 fastq.gz 3.1 GB
EGAF00004828057 fastq.gz 3.5 GB
EGAF00004828058 fastq.gz 1.4 GB
EGAF00004828059 fastq.gz 1.6 GB
EGAF00004828060 fastq.gz 1.5 GB
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EGAF00004828062 fastq.gz 1.5 GB
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EGAF00004828064 fastq.gz 1.5 GB
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EGAF00004828067 fastq.gz 1.7 GB
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EGAF00004828069 fastq.gz 1.8 GB
EGAF00004828070 fastq.gz 1.5 GB
EGAF00004828071 fastq.gz 1.7 GB
EGAF00004828072 fastq.gz 1.5 GB
EGAF00004828073 fastq.gz 1.7 GB
EGAF00004828074 fastq.gz 1.5 GB
EGAF00004828075 fastq.gz 1.7 GB
EGAF00004828076 fastq.gz 1.6 GB
EGAF00004828077 fastq.gz 1.7 GB
EGAF00004828078 fastq.gz 1.9 GB
EGAF00004828079 fastq.gz 2.3 GB
EGAF00004828080 fastq.gz 2.0 GB
EGAF00004828081 fastq.gz 2.3 GB
EGAF00004828082 fastq.gz 1.8 GB
EGAF00004828083 fastq.gz 2.1 GB
EGAF00004828084 fastq.gz 1.9 GB
EGAF00004828085 fastq.gz 2.2 GB
EGAF00004828086 fastq.gz 1.5 GB
EGAF00004828087 fastq.gz 1.7 GB
EGAF00004828088 fastq.gz 1.6 GB
EGAF00004828089 fastq.gz 1.7 GB
EGAF00004828090 fastq.gz 1.5 GB
EGAF00004828091 fastq.gz 1.8 GB
EGAF00004828092 fastq.gz 1.6 GB
EGAF00004828093 fastq.gz 1.8 GB
EGAF00004828094 fastq.gz 1.8 GB
EGAF00004828095 fastq.gz 2.2 GB
EGAF00004828096 fastq.gz 1.9 GB
EGAF00004828097 fastq.gz 2.2 GB
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EGAF00004828099 fastq.gz 2.1 GB
EGAF00004828100 fastq.gz 1.8 GB
EGAF00004828101 fastq.gz 2.2 GB
EGAF00004828102 fastq.gz 1.6 GB
EGAF00004828103 fastq.gz 1.9 GB
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EGAF00004828105 fastq.gz 1.9 GB
EGAF00004828106 fastq.gz 1.8 GB
EGAF00004828107 fastq.gz 2.1 GB
EGAF00004828108 fastq.gz 1.8 GB
EGAF00004828109 fastq.gz 2.1 GB
EGAF00004828110 fastq.gz 1.8 GB
EGAF00004828111 fastq.gz 2.1 GB
EGAF00004828112 fastq.gz 1.8 GB
EGAF00004828113 fastq.gz 2.1 GB
EGAF00004828114 fastq.gz 1.7 GB
EGAF00004828115 fastq.gz 1.8 GB
EGAF00004828116 fastq.gz 1.7 GB
EGAF00004828117 fastq.gz 1.8 GB
EGAF00004828118 fastq.gz 1.7 GB
EGAF00004828119 fastq.gz 1.9 GB
EGAF00004828120 fastq.gz 1.7 GB
EGAF00004828121 fastq.gz 1.9 GB
EGAF00004828122 fastq.gz 1.7 GB
EGAF00004828123 fastq.gz 2.0 GB
EGAF00004828124 fastq.gz 1.7 GB
EGAF00004828125 fastq.gz 2.0 GB
EGAF00004828126 fastq.gz 1.6 GB
EGAF00004828127 fastq.gz 1.9 GB
EGAF00004828128 fastq.gz 1.6 GB
EGAF00004828129 fastq.gz 1.9 GB
EGAF00004828130 fastq.gz 1.5 GB
EGAF00004828131 fastq.gz 1.7 GB
EGAF00004828132 fastq.gz 1.5 GB
EGAF00004828133 fastq.gz 1.7 GB
EGAF00004828134 fastq.gz 1.6 GB
EGAF00004828135 fastq.gz 1.9 GB
EGAF00004828136 fastq.gz 1.6 GB
EGAF00004828137 fastq.gz 1.9 GB
EGAF00004828138 fastq.gz 1.5 GB
EGAF00004828139 fastq.gz 1.6 GB
EGAF00004828140 fastq.gz 1.5 GB
EGAF00004828141 fastq.gz 1.7 GB
EGAF00004828142 fastq.gz 1.6 GB
EGAF00004828143 fastq.gz 1.9 GB
EGAF00004828144 fastq.gz 1.6 GB
EGAF00004828145 fastq.gz 1.9 GB
EGAF00004828146 fastq.gz 2.0 GB
EGAF00004828147 fastq.gz 2.3 GB
EGAF00004828148 fastq.gz 2.0 GB
EGAF00004828149 fastq.gz 2.3 GB
EGAF00004828150 fastq.gz 1.5 GB
EGAF00004828151 fastq.gz 1.7 GB
EGAF00004828152 fastq.gz 1.5 GB
EGAF00004828153 fastq.gz 1.7 GB
EGAF00004828154 fastq.gz 1.5 GB
EGAF00004828155 fastq.gz 1.6 GB
EGAF00004828156 fastq.gz 1.5 GB
EGAF00004828157 fastq.gz 1.6 GB
EGAF00004828158 fastq.gz 1.7 GB
EGAF00004828159 fastq.gz 1.9 GB
EGAF00004828160 fastq.gz 1.7 GB
EGAF00004828161 fastq.gz 2.0 GB
EGAF00004828162 fastq.gz 1.7 GB
EGAF00004828163 fastq.gz 2.0 GB
EGAF00004828164 fastq.gz 1.7 GB
EGAF00004828165 fastq.gz 2.0 GB
EGAF00004828166 fastq.gz 1.5 GB
EGAF00004828167 fastq.gz 1.8 GB
EGAF00004828168 fastq.gz 1.5 GB
EGAF00004828169 fastq.gz 1.8 GB
EGAF00004828170 fastq.gz 1.8 GB
EGAF00004828171 fastq.gz 2.1 GB
EGAF00004828172 fastq.gz 1.8 GB
EGAF00004828173 fastq.gz 2.1 GB
EGAF00004829291 fastq.gz 13.3 GB
EGAF00004829292 fastq.gz 14.6 GB
EGAF00004829293 fastq.gz 13.2 GB
EGAF00004829294 fastq.gz 14.3 GB
EGAF00004829295 fastq.gz 13.4 GB
EGAF00004829296 fastq.gz 14.5 GB
EGAF00004829297 fastq.gz 2.0 GB
EGAF00004829298 fastq.gz 2.3 GB
EGAF00004829299 fastq.gz 1.9 GB
EGAF00004829300 fastq.gz 2.0 GB
EGAF00004829301 fastq.gz 12.5 GB
EGAF00004829302 fastq.gz 13.6 GB
EGAF00004829303 fastq.gz 12.4 GB
EGAF00004829304 fastq.gz 13.4 GB
EGAF00004829305 fastq.gz 12.5 GB
EGAF00004829306 fastq.gz 13.5 GB
EGAF00004829307 fastq.gz 2.0 GB
EGAF00004829308 fastq.gz 2.2 GB
EGAF00004829309 fastq.gz 1.7 GB
EGAF00004829310 fastq.gz 1.8 GB
1981 Files (8.9 TB)