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Biological and Therapeutic Implications of a Unique Subtype of NPM1 Mutated AML (RNAseq Data)

This dataset contains 91 RNAseq paired reads, in fastq format. Samples were collected from fresh bone marrow and peripheral blood sample from AML patients.

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Access to data generated by UHN is made available by completing the data access agreement for review by the data access committee and will be granted to qualified investigators for appropriate use.

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom the Data Access Committee (DAC) grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: The Principal Investigator and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. University Health Network: The University Health Network (UHN) is the largest clinical and research hospital in Canada. UHN is affiliated with the University of Toronto and is a member of the Toronto Academic Health Science Network. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines ( ) and the Toronto Statement ( This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) ( ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) ( ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify the DAC within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify the DAC prior to any significant changes to the protocol for the Project. 14. The User Institution will notify the DAC as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. The DAC may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of the province of Ontario and PHIPA. Agreed for User Institution Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for The Data Access Committee Signature: Name: Title: Date: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001004872 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00004922734 fastq.gz 1.2 GB
EGAF00004922735 fastq.gz 1.2 GB
EGAF00004922736 fastq.gz 1.5 GB
EGAF00004922737 fastq.gz 1.5 GB
EGAF00004922738 fastq.gz 1.3 GB
EGAF00004922739 fastq.gz 1.3 GB
EGAF00004922740 fastq.gz 1.8 GB
EGAF00004922741 fastq.gz 1.8 GB
EGAF00004922742 fastq.gz 1.9 GB
EGAF00004922743 fastq.gz 2.0 GB
EGAF00004922744 fastq.gz 1.3 GB
EGAF00004922745 fastq.gz 1.4 GB
EGAF00004922746 fastq.gz 1.3 GB
EGAF00004922747 fastq.gz 1.3 GB
EGAF00004922750 fastq.gz 2.5 GB
EGAF00004922751 fastq.gz 2.5 GB
EGAF00004922753 fastq.gz 731.9 MB
EGAF00004922754 fastq.gz 757.5 MB
EGAF00004922755 fastq.gz 1.1 GB
EGAF00004922756 fastq.gz 1.1 GB
EGAF00004922757 fastq.gz 1.5 GB
EGAF00004922758 fastq.gz 1.5 GB
EGAF00004922759 fastq.gz 663.4 MB
EGAF00004922760 fastq.gz 684.2 MB
EGAF00004922761 fastq.gz 1.1 GB
EGAF00004922762 fastq.gz 1.1 GB
EGAF00004922764 fastq.gz 887.1 MB
EGAF00004922765 fastq.gz 908.0 MB
EGAF00004922766 fastq.gz 1.1 GB
EGAF00004922767 fastq.gz 1.1 GB
EGAF00004922768 fastq.gz 1.4 GB
EGAF00004922769 fastq.gz 1.5 GB
EGAF00004922770 fastq.gz 987.0 MB
EGAF00004922771 fastq.gz 1.0 GB
EGAF00004922772 fastq.gz 314.6 MB
EGAF00004922773 fastq.gz 323.5 MB
EGAF00004922774 fastq.gz 1.1 GB
EGAF00004922775 fastq.gz 1.2 GB
EGAF00004922776 fastq.gz 1.1 GB
EGAF00004922777 fastq.gz 1.1 GB
EGAF00004922778 fastq.gz 1.1 GB
EGAF00004922779 fastq.gz 1.1 GB
EGAF00004922780 fastq.gz 926.8 MB
EGAF00004922781 fastq.gz 949.7 MB
EGAF00004922782 fastq.gz 656.6 MB
EGAF00004922783 fastq.gz 679.0 MB
EGAF00004922784 fastq.gz 1.1 GB
EGAF00004922785 fastq.gz 1.2 GB
EGAF00004922786 fastq.gz 481.5 MB
EGAF00004922787 fastq.gz 503.2 MB
EGAF00004922788 fastq.gz 1.0 GB
EGAF00004922789 fastq.gz 1.1 GB
EGAF00004922790 fastq.gz 469.2 MB
EGAF00004922791 fastq.gz 488.5 MB
EGAF00004922792 fastq.gz 1.0 GB
EGAF00004922793 fastq.gz 1.1 GB
EGAF00004922794 fastq.gz 559.2 MB
EGAF00004922795 fastq.gz 587.4 MB
EGAF00004922796 fastq.gz 853.5 MB
EGAF00004922797 fastq.gz 891.6 MB
EGAF00004922798 fastq.gz 830.4 MB
EGAF00004922799 fastq.gz 864.1 MB
EGAF00004922800 fastq.gz 1.2 GB
EGAF00004922801 fastq.gz 1.2 GB
EGAF00004922802 fastq.gz 1.2 GB
EGAF00004922803 fastq.gz 1.2 GB
EGAF00004922804 fastq.gz 845.8 MB
EGAF00004922805 fastq.gz 867.5 MB
EGAF00004922806 fastq.gz 809.8 MB
EGAF00004922807 fastq.gz 842.1 MB
EGAF00004922808 fastq.gz 1.2 GB
EGAF00004922809 fastq.gz 1.3 GB
EGAF00004922810 fastq.gz 1.3 GB
EGAF00004922811 fastq.gz 1.3 GB
EGAF00004922812 fastq.gz 2.1 GB
EGAF00004922813 fastq.gz 2.1 GB
EGAF00004922814 fastq.gz 1.4 GB
EGAF00004922815 fastq.gz 1.4 GB
EGAF00004922816 fastq.gz 722.6 MB
EGAF00004922817 fastq.gz 749.1 MB
EGAF00004922820 fastq.gz 566.7 MB
EGAF00004922821 fastq.gz 593.1 MB
EGAF00004922822 fastq.gz 529.5 MB
EGAF00004922823 fastq.gz 550.2 MB
EGAF00004922824 fastq.gz 544.9 MB
EGAF00004922825 fastq.gz 568.4 MB
EGAF00004922826 fastq.gz 868.5 MB
EGAF00004922827 fastq.gz 906.3 MB
EGAF00004922828 fastq.gz 2.0 GB
EGAF00004922829 fastq.gz 2.0 GB
EGAF00004922830 fastq.gz 1.8 GB
EGAF00004922831 fastq.gz 1.9 GB
EGAF00004922832 fastq.gz 1.1 GB
EGAF00004922833 fastq.gz 1.2 GB
EGAF00004922835 fastq.gz 1.7 GB
EGAF00004922836 fastq.gz 1.8 GB
EGAF00004922837 fastq.gz 1.2 GB
EGAF00004922838 fastq.gz 1.2 GB
EGAF00004922839 fastq.gz 1.0 GB
EGAF00004922840 fastq.gz 1.1 GB
EGAF00004922841 fastq.gz 1.1 GB
EGAF00004922842 fastq.gz 1.1 GB
EGAF00004922843 fastq.gz 789.6 MB
EGAF00004922844 fastq.gz 817.9 MB
EGAF00004922851 fastq.gz 1.2 GB
EGAF00004922852 fastq.gz 1.2 GB
EGAF00004922853 fastq.gz 550.0 MB
EGAF00004922854 fastq.gz 573.0 MB
EGAF00004922856 fastq.gz 2.1 GB
EGAF00004922857 fastq.gz 2.2 GB
EGAF00004922858 fastq.gz 1.2 GB
EGAF00004922859 fastq.gz 1.2 GB
EGAF00004922860 fastq.gz 993.2 MB
EGAF00004922861 fastq.gz 1.0 GB
EGAF00004922862 fastq.gz 758.9 MB
EGAF00004922863 fastq.gz 781.2 MB
EGAF00004922864 fastq.gz 1.1 GB
EGAF00004922865 fastq.gz 1.1 GB
EGAF00004922866 fastq.gz 261.8 MB
EGAF00004922867 fastq.gz 268.6 MB
EGAF00004922868 fastq.gz 1.9 GB
EGAF00004922869 fastq.gz 2.0 GB
EGAF00004922870 fastq.gz 1.8 GB
EGAF00004922871 fastq.gz 1.8 GB
EGAF00004922872 fastq.gz 820.1 MB
EGAF00004922873 fastq.gz 853.5 MB
EGAF00004922874 fastq.gz 1.6 GB
EGAF00004922875 fastq.gz 1.6 GB
EGAF00004922876 fastq.gz 1.3 GB
EGAF00004922877 fastq.gz 1.3 GB
EGAF00004922878 fastq.gz 800.9 MB
EGAF00004922879 fastq.gz 828.4 MB
EGAF00004922880 fastq.gz 1.0 GB
EGAF00004922881 fastq.gz 1.0 GB
EGAF00004922882 fastq.gz 1.8 GB
EGAF00004922883 fastq.gz 1.9 GB
EGAF00004922884 fastq.gz 754.0 MB
EGAF00004922885 fastq.gz 783.9 MB
EGAF00004922886 fastq.gz 1.2 GB
EGAF00004922887 fastq.gz 1.2 GB
EGAF00004922888 fastq.gz 542.7 MB
EGAF00004922889 fastq.gz 567.7 MB
EGAF00004922890 fastq.gz 1.2 GB
EGAF00004922891 fastq.gz 1.3 GB
EGAF00004922892 fastq.gz 2.4 GB
EGAF00004922893 fastq.gz 2.5 GB
EGAF00004922894 fastq.gz 572.9 MB
EGAF00004922895 fastq.gz 593.2 MB
EGAF00004922896 fastq.gz 1.1 GB
EGAF00004922897 fastq.gz 1.1 GB
EGAF00004922898 fastq.gz 1.1 GB
EGAF00004922899 fastq.gz 1.1 GB
EGAF00004922900 fastq.gz 854.1 MB
EGAF00004922901 fastq.gz 881.5 MB
EGAF00004922902 fastq.gz 1.4 GB
EGAF00004922903 fastq.gz 1.5 GB
EGAF00004922904 fastq.gz 1.1 GB
EGAF00004922905 fastq.gz 1.1 GB
EGAF00004922906 fastq.gz 474.9 MB
EGAF00004922907 fastq.gz 493.6 MB
EGAF00004922908 fastq.gz 460.9 MB
EGAF00004922909 fastq.gz 477.1 MB
EGAF00004922910 fastq.gz 1.1 GB
EGAF00004922911 fastq.gz 1.1 GB
EGAF00004922914 fastq.gz 797.1 MB
EGAF00004922915 fastq.gz 826.0 MB
EGAF00004922918 fastq.gz 889.1 MB
EGAF00004922919 fastq.gz 902.4 MB
EGAF00004922920 fastq.gz 1.9 GB
EGAF00004922921 fastq.gz 1.9 GB
EGAF00004922922 fastq.gz 1.5 GB
EGAF00004922923 fastq.gz 1.5 GB
EGAF00004922924 fastq.gz 1.9 GB
EGAF00004922925 fastq.gz 1.9 GB
EGAF00004922926 fastq.gz 1.2 GB
EGAF00004922927 fastq.gz 1.2 GB
EGAF00004922928 fastq.gz 631.4 MB
EGAF00004922929 fastq.gz 659.4 MB
EGAF00004922930 fastq.gz 650.9 MB
EGAF00004922931 fastq.gz 682.5 MB
EGAF00004922932 fastq.gz 888.8 MB
EGAF00004922933 fastq.gz 916.5 MB
182 Files (205.6 GB)