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Peripheral immunoprofiling of stratifies COVID-19 patients based on disease-specific neutrophil signatures

The SARS-CoV-2 pandemic has led to increasing numbers of COVID-19 patients all over the world. Aetiopathologies range from no symptoms, mild flu-like to severe cases succumbing to respiratory failure. Reports on a dysregulated immune system in the severe cases, showing similarities to cytokine release syndrome, calls for better characterization and understanding of the changes in the immune system as well as their variance across COVID-19 patients in order to be able to design according to host-directed therapies. Here, we profiled blood transcriptomes of 39 COVID-19 patients and 10 control donors. Enriched granulocyte signatures in whole blood samples were verified in granulocyte samples from 49 COVID-19 patients in a second cohort.

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whole blood COVID-19 data access policy

Access to data generated is made available by completing the data access agreement for review by the data access committee and will be granted exclusively to qualified investigators for appropriate use.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001004503 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00004150754 fastq.gz 1.2 GB
EGAF00004150755 fastq.gz 1.3 GB
EGAF00004150756 fastq.gz 1.2 GB
EGAF00004150757 fastq.gz 1.3 GB
EGAF00004150758 fastq.gz 1.2 GB
EGAF00004150759 fastq.gz 1.3 GB
EGAF00004150760 fastq.gz 1.2 GB
EGAF00004150761 fastq.gz 1.4 GB
EGAF00004150762 fastq.gz 1.0 GB
EGAF00004150763 fastq.gz 1.2 GB
EGAF00004150764 fastq.gz 1.1 GB
EGAF00004150765 fastq.gz 1.2 GB
EGAF00004150766 fastq.gz 1.1 GB
EGAF00004150767 fastq.gz 1.3 GB
EGAF00004150768 fastq.gz 1.0 GB
EGAF00004150769 fastq.gz 1.1 GB
EGAF00004150770 fastq.gz 1.4 GB
EGAF00004150771 fastq.gz 1.6 GB
EGAF00004150772 fastq.gz 1.3 GB
EGAF00004150773 fastq.gz 1.5 GB
EGAF00004150774 fastq.gz 1.3 GB
EGAF00004150775 fastq.gz 1.5 GB
EGAF00004150776 fastq.gz 1.3 GB
EGAF00004150777 fastq.gz 1.5 GB
EGAF00004150778 fastq.gz 1.1 GB
EGAF00004150779 fastq.gz 1.3 GB
EGAF00004150780 fastq.gz 1.2 GB
EGAF00004150781 fastq.gz 1.4 GB
EGAF00004150782 fastq.gz 1.4 GB
EGAF00004150783 fastq.gz 1.6 GB
EGAF00004150784 fastq.gz 1.1 GB
EGAF00004150785 fastq.gz 1.3 GB
EGAF00004150786 fastq.gz 1.5 GB
EGAF00004150787 fastq.gz 1.7 GB
EGAF00004150788 fastq.gz 998.6 MB
EGAF00004150789 fastq.gz 1.1 GB
EGAF00004150790 fastq.gz 1.2 GB
EGAF00004150791 fastq.gz 1.3 GB
EGAF00004150792 fastq.gz 1.0 GB
EGAF00004150793 fastq.gz 1.2 GB
EGAF00004150794 fastq.gz 1.4 GB
EGAF00004150795 fastq.gz 1.5 GB
EGAF00004150796 fastq.gz 1.2 GB
EGAF00004150797 fastq.gz 1.4 GB
EGAF00004150798 fastq.gz 1.3 GB
EGAF00004150799 fastq.gz 1.4 GB
EGAF00004150800 fastq.gz 1.4 GB
EGAF00004150801 fastq.gz 1.5 GB
EGAF00004150802 fastq.gz 1.3 GB
EGAF00004150803 fastq.gz 1.4 GB
EGAF00004150804 fastq.gz 930.7 MB
EGAF00004150805 fastq.gz 1.1 GB
EGAF00004150806 fastq.gz 1.1 GB
EGAF00004150807 fastq.gz 1.2 GB
EGAF00004150808 fastq.gz 1.3 GB
EGAF00004150809 fastq.gz 1.4 GB
EGAF00004150810 fastq.gz 1.3 GB
EGAF00004150811 fastq.gz 1.5 GB
EGAF00004150812 fastq.gz 1.6 GB
EGAF00004150813 fastq.gz 1.8 GB
EGAF00004923894 fastq.gz 5.3 GB
EGAF00004923895 fastq.gz 5.6 GB
EGAF00004923896 fastq.gz 2.8 GB
EGAF00004923897 fastq.gz 3.0 GB
EGAF00004923898 fastq.gz 4.9 GB
EGAF00004923899 fastq.gz 5.1 GB
EGAF00004923900 fastq.gz 2.3 GB
EGAF00004923901 fastq.gz 2.4 GB
EGAF00004923902 fastq.gz 2.5 GB
EGAF00004923903 fastq.gz 2.6 GB
EGAF00004923904 fastq.gz 3.7 GB
EGAF00004923905 fastq.gz 4.0 GB
EGAF00004923906 fastq.gz 995.1 MB
EGAF00004923907 fastq.gz 1.1 GB
EGAF00004923908 fastq.gz 2.7 GB
EGAF00004923909 fastq.gz 2.9 GB
EGAF00004923910 fastq.gz 2.5 GB
EGAF00004923911 fastq.gz 2.7 GB
EGAF00004923912 fastq.gz 2.8 GB
EGAF00004923913 fastq.gz 2.9 GB
EGAF00004923914 fastq.gz 2.8 GB
EGAF00004923915 fastq.gz 3.0 GB
82 Files (146.6 GB)