DNA repair knockouts
We generated HPRT-only knockout lines as well as the combination of HPRT with MSH2, UNG and XPC. Whole genome sequencing was performed on generated clones and subclones. By subtracting variants present in the clones from those in the subclones, the somatic mutations, that accumulated in between the clonal steps, were determined.
- 11 samples
- DAC: EGAC00001001864
- Technologies: HiSeq X Ten, Illumina NovaSeq 6000
The Princess Maxima Center for pediatric oncology default access policy to enable re-production of research and re-use of data for scientific purposes.
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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
Study ID | Study Title | Study Type |
---|---|---|
EGAS00001004789 | Whole Genome Sequencing |
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