About file location

As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis

Single-cell RNA-Sequencing of three primary breast cancers, two primary prostate cancers, and a metastatic melanoma sample from Wu et al. (2021) Genome Medicine study. Each tumour was sequenced across different cryopreservation conditions including Fresh Tissue (FT), cryopreserved single-cell suspensions (CCS), cryopreserved solid tissue fragments (CT) and a cryopreserved after overnight cold storage (CO). Data was generated using the Chromium controller (10X Genomics) and sequenced on the NextSeq platform.

Request Access

The EGA-Garvan DATA ACCESS APPLICATION + AGREEMENT for data related to the scRNAseq cryopreservation study

The EGA-Garvan DATA ACCESS APPLICATION + AGREEMENT These terms and conditions are based on the standard EGA Data Access Agreement and govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. 1. Definitions Authorised Personnel: The individuals at the User Institution to whom Garvan grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: Garvan and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. Garvan means Garvan located at 384 Victoria Street, Darlinghurst, Sydney, NSW 2010 Australia. 2. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 3. The User Institution warrants that the Project for which the Data is being sought has been approved by a human research ethics committee. 4. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it: (a) Must not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants; (b) Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data; 5. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 6. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 7. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 8. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 9. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 10. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 11. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data or any of it. 12. The User Institution must notify Garvan of any patent application filed in respect of the Project, at the time of filing and provide Garvan (or its nominee) with sufficient information to determine whether there has been a breach of clause 11. If there has been a breach of clause 11 then the User Institution must amend its patent application to eliminate the breach or withdraw it. The information provided to Garvan pursuant to this clause will be treated as confidential to the User Institution. 13. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 14. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 15. The User Institution will notify Garvan within 30 days of any changes or departures of Authorised Personnel. 16. The User Institution will notify Garvan prior to any significant changes to the protocol for the Project. 17. The User Institution will notify Garvan immediately as soon as it becomes aware of: (a) any breach of this agreement; (b) any actual, suspected or threatened breach of clause 3 and 4 and any other confidentiality obligations to Garvan. 18. Garvan may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 19. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than Garvan. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 20. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 21. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 22. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of New South Wales, Australia and shall be subject to the exclusive jurisdiction of the courts that operate in New South Wales without reference to its laws regarding the conflicts of laws. 23. The User Institution agrees that Garvan has absolute discretion as to whether or not to grant access to these Data / to approve the User Institution’s application to access the Data. Agreed for User Institution Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for Garvan Institute of Medical Research Signature: Name: Title: Date: Please see overleaf for: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY APPENDIX I – DATASET DETAILS 1. Dataset reference (EGA Study ID and Dataset Details) 2. Name of project that created the dataset 3. Name of Responsible owner of the dataset 4. Names of other data producers / collaborators 5. Specific limitations on areas of research 6. Minimum protection measures required File access: Data can be held in unencrypted files on an institutional compute system, with Unix user group read/write access for one or more appropriate groups but not Unix world read/write access behind a secure firewall. Laptops holding these data should have password protected logins and screenlocks (set to lock after 5 min of inactivity). If held on USB keys or other portable hard drives, the data must be encrypted. APPENDIX II – PROJECT DETAILS (to be completed by the Requestor) 1. Details of dataset requested i.e., EGA Study and Dataset Accession Number 2. Brief abstract of the Project in which the Data will be used (500 words max) 3. All Individuals who the User Institution would like named as registered users Name of Registered User Email Job Title Supervisor* 4. All Individuals that should have an account created at the EGA Name of Registered User Email Job Title 5. User Institution Institution Name: Address: Phone: Email: 6. Principal Investigator (User) Name: Address: Phone Email: APPENDIX III – PUBLICATION POLICY 1. Moratorium Garvan intend to publish the results of their analysis of this dataset and do not consider its deposition into public databases to be the equivalent of such publications. Garvan anticipate that the dataset could be useful to other qualified researchers for a variety of purposes. However, some areas of work are subject to a publication moratorium. The publication moratorium covers any publications (including oral communications) that describe the use of the dataset. For research papers, submission for publication should not occur until 6 months after these data were first made available on the relevant hosting database, unless Garvan has provided written consent to earlier submission. 2. Acknowledgement and approvals In any publications based on these data, please describe how the data can be accessed, including the name of the hosting database (e.g., The European Genome-phenome Archive at the European Bioinformatics Institute) and its accession numbers (e.g., EGAS00000000029), and acknowledge its use in a form agreed by the User Institution with Garvan, but at minimum by citing the publication that first describes this dataset. The User Institution is required to include an appropriate acknowledgement (and authorship if deemed necessary) in any Publication that makes use of or reference to a Garvan dataset in accordance with the following terms. Publications that make use of Data will be required to acknowledge Garvan in the acknowledgements section of the Publication. An example of a proper attribution is: "The results published or shown here are in whole or part based upon data generated by the Garvan Institute of Medical Research.”

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001005115 Transcriptome Analysis

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Quality Report
Located in
i
EGAF00005092734 fastq.gz 221.8 MB Report
EGAF00005092735 fastq.gz 660.4 MB Report
EGAF00005092736 fastq.gz 1.9 GB Report
EGAF00005092737 fastq.gz 220.8 MB Report
EGAF00005092738 fastq.gz 668.7 MB Report
EGAF00005092739 fastq.gz 1.9 GB Report
EGAF00005092740 fastq.gz 783.0 MB Report
EGAF00005092741 fastq.gz 2.2 GB Report
EGAF00005092742 fastq.gz 785.3 MB Report
EGAF00005092743 fastq.gz 2.2 GB Report
EGAF00005092744 fastq.gz 761.9 MB Report
EGAF00005092745 fastq.gz 2.1 GB Report
EGAF00005092746 fastq.gz 253.6 MB Report
EGAF00005092747 fastq.gz 258.2 MB Report
EGAF00005092748 fastq.gz 653.1 MB Report
EGAF00005092749 fastq.gz 1.9 GB Report
EGAF00005092750 fastq.gz 524.3 MB Report
EGAF00005092751 fastq.gz 525.9 MB Report
EGAF00005092752 fastq.gz 776.4 MB Report
EGAF00005092753 fastq.gz 2.2 GB Report
EGAF00005092754 fastq.gz 881.4 MB Report
EGAF00005092755 fastq.gz 2.5 GB Report
EGAF00005092756 fastq.gz 292.3 MB Report
EGAF00005092757 fastq.gz 864.1 MB Report
EGAF00005092758 fastq.gz 2.5 GB Report
EGAF00005092759 fastq.gz 684.5 MB Report
EGAF00005092760 fastq.gz 1.9 GB Report
EGAF00005092761 fastq.gz 1.2 GB Report
EGAF00005092762 fastq.gz 3.4 GB Report
EGAF00005092763 fastq.gz 1.2 GB Report
EGAF00005092764 fastq.gz 3.3 GB Report
EGAF00005092765 fastq.gz 265.7 MB Report
EGAF00005092766 fastq.gz 1.1 GB Report
EGAF00005092767 fastq.gz 3.2 GB Report
EGAF00005092768 fastq.gz 1.1 GB Report
EGAF00005092769 fastq.gz 3.2 GB Report
EGAF00005092770 fastq.gz 1.2 GB Report
EGAF00005092771 fastq.gz 3.3 GB Report
EGAF00005092772 fastq.gz 258.6 MB Report
EGAF00005092773 fastq.gz 263.2 MB Report
EGAF00005092774 fastq.gz 254.4 MB Report
EGAF00005092775 fastq.gz 215.1 MB Report
EGAF00005092776 fastq.gz 1.7 GB Report
EGAF00005092777 fastq.gz 4.9 GB Report
EGAF00005092778 fastq.gz 214.1 MB Report
EGAF00005092779 fastq.gz 402.6 MB Report
EGAF00005092780 fastq.gz 374.0 MB Report
EGAF00005092781 fastq.gz 1.7 GB Report
EGAF00005092782 fastq.gz 4.9 GB Report
EGAF00005092783 fastq.gz 363.8 MB Report
EGAF00005092784 fastq.gz 216.0 MB Report
EGAF00005092785 fastq.gz 1.4 GB Report
EGAF00005092786 fastq.gz 3.9 GB Report
EGAF00005092787 fastq.gz 301.7 MB Report
EGAF00005092788 fastq.gz 1.3 GB Report
EGAF00005092789 fastq.gz 3.8 GB Report
EGAF00005092790 fastq.gz 382.6 MB Report
EGAF00005092791 fastq.gz 452.5 MB Report
EGAF00005092792 fastq.gz 462.7 MB Report
EGAF00005092793 fastq.gz 448.5 MB Report
EGAF00005092794 fastq.gz 686.8 MB Report
EGAF00005092795 fastq.gz 2.0 GB Report
EGAF00005092796 fastq.gz 1.4 GB Report
EGAF00005092797 fastq.gz 4.3 GB Report
EGAF00005092798 fastq.gz 521.1 MB Report
EGAF00005092799 fastq.gz 693.9 MB Report
EGAF00005092800 fastq.gz 2.0 GB Report
EGAF00005092801 fastq.gz 1.5 GB Report
EGAF00005092802 fastq.gz 4.3 GB Report
EGAF00005092803 fastq.gz 526.1 MB Report
EGAF00005092804 fastq.gz 376.8 MB Report
EGAF00005092805 fastq.gz 284.3 MB Report
EGAF00005092806 fastq.gz 282.0 MB Report
EGAF00005092807 fastq.gz 376.3 MB Report
EGAF00005092808 fastq.gz 291.2 MB Report
EGAF00005092809 fastq.gz 372.3 MB Report
EGAF00005092810 fastq.gz 1.3 GB Report
EGAF00005092811 fastq.gz 3.7 GB Report
EGAF00005092812 fastq.gz 746.8 MB Report
EGAF00005092813 fastq.gz 2.1 GB Report
EGAF00005092814 fastq.gz 759.5 MB Report
EGAF00005092815 fastq.gz 2.1 GB Report
EGAF00005092816 fastq.gz 771.4 MB Report
EGAF00005092817 fastq.gz 2.2 GB Report
EGAF00005092818 fastq.gz 462.7 MB Report
EGAF00005092819 fastq.gz 1.7 GB Report
EGAF00005092820 fastq.gz 4.9 GB Report
EGAF00005092821 fastq.gz 461.8 MB Report
EGAF00005092822 fastq.gz 1.2 GB Report
EGAF00005092823 fastq.gz 3.3 GB Report
EGAF00005092824 fastq.gz 450.0 MB Report
EGAF00005092825 fastq.gz 757.3 MB Report
EGAF00005092826 fastq.gz 2.2 GB Report
EGAF00005092827 fastq.gz 906.2 MB Report
EGAF00005092828 fastq.gz 2.5 GB Report
EGAF00005092829 fastq.gz 905.4 MB Report
EGAF00005092830 fastq.gz 2.5 GB Report
EGAF00005092831 fastq.gz 251.2 MB Report
EGAF00005092832 fastq.gz 1.2 GB Report
EGAF00005092833 fastq.gz 3.3 GB Report
EGAF00005092834 fastq.gz 899.5 MB Report
EGAF00005092835 fastq.gz 2.6 GB Report
EGAF00005092836 fastq.gz 1.1 GB Report
EGAF00005092837 fastq.gz 3.2 GB Report
EGAF00005092838 fastq.gz 259.5 MB Report
EGAF00005092839 fastq.gz 1.2 GB Report
EGAF00005092840 fastq.gz 3.2 GB Report
EGAF00005092841 fastq.gz 264.1 MB Report
EGAF00005092842 fastq.gz 1.1 GB Report
EGAF00005092843 fastq.gz 3.1 GB Report
EGAF00005092844 fastq.gz 266.3 MB Report
EGAF00005092845 fastq.gz 433.5 MB Report
EGAF00005092846 fastq.gz 267.6 MB Report
EGAF00005092847 fastq.gz 896.6 MB Report
EGAF00005092848 fastq.gz 2.4 GB Report
EGAF00005092849 fastq.gz 883.1 MB Report
EGAF00005092850 fastq.gz 2.5 GB Report
EGAF00005092851 fastq.gz 266.7 MB Report
EGAF00005092852 fastq.gz 265.2 MB Report
EGAF00005092853 fastq.gz 851.9 MB Report
EGAF00005092854 fastq.gz 2.4 GB Report
EGAF00005092855 fastq.gz 853.7 MB Report
EGAF00005092856 fastq.gz 2.4 GB Report
EGAF00005092857 fastq.gz 766.6 MB Report
EGAF00005092858 fastq.gz 2.2 GB Report
EGAF00005092859 fastq.gz 391.3 MB Report
EGAF00005092860 fastq.gz 842.5 MB Report
EGAF00005092861 fastq.gz 2.4 GB Report
EGAF00005092862 fastq.gz 390.8 MB Report
EGAF00005092863 fastq.gz 704.3 MB Report
EGAF00005092864 fastq.gz 2.0 GB Report
EGAF00005092865 fastq.gz 1.3 GB Report
EGAF00005092866 fastq.gz 3.7 GB Report
EGAF00005092867 fastq.gz 764.2 MB Report
EGAF00005092868 fastq.gz 2.2 GB Report
EGAF00005092869 fastq.gz 403.0 MB Report
EGAF00005092870 fastq.gz 216.5 MB Report
EGAF00005092871 fastq.gz 1.7 GB Report
EGAF00005092872 fastq.gz 4.9 GB Report
EGAF00005092873 fastq.gz 274.8 MB Report
EGAF00005092874 fastq.gz 1.4 GB Report
EGAF00005092875 fastq.gz 4.2 GB Report
EGAF00005092876 fastq.gz 1.3 GB Report
EGAF00005092877 fastq.gz 4.0 GB Report
EGAF00005092878 fastq.gz 661.3 MB Report
EGAF00005092879 fastq.gz 1.9 GB Report
EGAF00005092880 fastq.gz 773.4 MB Report
EGAF00005092881 fastq.gz 2.2 GB Report
EGAF00005092882 fastq.gz 671.2 MB Report
EGAF00005092883 fastq.gz 1.9 GB Report
EGAF00005092884 fastq.gz 651.6 MB Report
EGAF00005092885 fastq.gz 1.8 GB Report
EGAF00005092886 fastq.gz 227.6 MB Report
EGAF00005092887 fastq.gz 223.5 MB Report
EGAF00005092888 fastq.gz 873.0 MB Report
EGAF00005092889 fastq.gz 2.5 GB Report
EGAF00005092890 fastq.gz 767.5 MB Report
EGAF00005092891 fastq.gz 2.2 GB Report
EGAF00005092892 fastq.gz 249.9 MB Report
EGAF00005092893 fastq.gz 292.3 MB Report
EGAF00005092894 fastq.gz 290.7 MB Report
EGAF00005092895 fastq.gz 299.2 MB Report
EGAF00005092896 fastq.gz 891.2 MB Report
EGAF00005092897 fastq.gz 2.5 GB Report
EGAF00005092898 fastq.gz 923.7 MB Report
EGAF00005092899 fastq.gz 2.6 GB Report
EGAF00005092900 fastq.gz 756.8 MB Report
EGAF00005092901 fastq.gz 2.2 GB Report
EGAF00005092902 fastq.gz 1.4 GB Report
EGAF00005092903 fastq.gz 3.8 GB Report
EGAF00005092904 fastq.gz 275.8 MB Report
EGAF00005092905 fastq.gz 1.4 GB Report
EGAF00005092906 fastq.gz 3.9 GB Report
EGAF00005092907 fastq.gz 904.3 MB Report
EGAF00005092908 fastq.gz 2.5 GB Report
EGAF00005092909 fastq.gz 273.1 MB Report
EGAF00005092910 fastq.gz 1.2 GB Report
EGAF00005092911 fastq.gz 3.3 GB Report
EGAF00005092912 fastq.gz 445.1 MB Report
EGAF00005092913 fastq.gz 433.4 MB Report
EGAF00005092914 fastq.gz 1.2 GB Report
EGAF00005092915 fastq.gz 3.4 GB Report
EGAF00005092916 fastq.gz 303.2 MB Report
EGAF00005092917 fastq.gz 302.0 MB Report
EGAF00005092918 fastq.gz 751.8 MB Report
EGAF00005092919 fastq.gz 2.2 GB Report
EGAF00005092920 fastq.gz 220.4 MB Report
EGAF00005092921 fastq.gz 215.3 MB Report
EGAF00005092922 fastq.gz 218.0 MB Report
EGAF00005092923 fastq.gz 221.5 MB Report
EGAF00005092924 fastq.gz 1.3 GB Report
EGAF00005092925 fastq.gz 3.8 GB Report
EGAF00005092926 fastq.gz 1.4 GB Report
EGAF00005092927 fastq.gz 3.8 GB Report
EGAF00005092928 fastq.gz 655.0 MB Report
EGAF00005092929 fastq.gz 1.9 GB Report
EGAF00005092930 fastq.gz 787.8 MB Report
EGAF00005092931 fastq.gz 2.2 GB Report
EGAF00005092932 fastq.gz 361.0 MB Report
EGAF00005092933 fastq.gz 858.6 MB Report
EGAF00005092934 fastq.gz 2.4 GB Report
EGAF00005092935 fastq.gz 303.9 MB Report
EGAF00005092936 fastq.gz 652.8 MB Report
EGAF00005092937 fastq.gz 1.8 GB Report
EGAF00005092938 fastq.gz 275.8 MB Report
EGAF00005092939 fastq.gz 364.0 MB Report
EGAF00005092940 fastq.gz 424.2 MB Report
EGAF00005092941 fastq.gz 438.7 MB Report
EGAF00005092942 fastq.gz 905.4 MB Report
EGAF00005092943 fastq.gz 2.6 GB Report
EGAF00005092944 fastq.gz 428.2 MB Report
EGAF00005092945 fastq.gz 261.7 MB Report
EGAF00005092946 fastq.gz 283.9 MB Report
EGAF00005092947 fastq.gz 259.0 MB Report
EGAF00005092948 fastq.gz 757.9 MB Report
EGAF00005092949 fastq.gz 2.2 GB Report
216 Files (298.5 GB)